Intervention Protocol

Interventions for treating osteonecrosis of the jaw bones associated with bisphosphonates

  1. Nicole B Vogt-Ferrier1,*,
  2. Max Hugentobler2,
  3. Brigitte Uebelhart3,
  4. Martin Tramèr4,
  5. Victoria Rollason5

Editorial Group: Cochrane Oral Health Group

Published Online: 14 APR 2010

DOI: 10.1002/14651858.CD008455

How to Cite

Vogt-Ferrier NB, Hugentobler M, Uebelhart B, Tramèr M, Rollason V. Interventions for treating osteonecrosis of the jaw bones associated with bisphosphonates (Protocol). Cochrane Database of Systematic Reviews 2010, Issue 4. Art. No.: CD008455. DOI: 10.1002/14651858.CD008455.

Author Information

  1. 1

    Hôpitaux Universitaires de Genève, Unité de Gérontopharmacologie Clinique, Thônex, Switzerland

  2. 2

    Geneva University Hospitals, Division of Maxillo-Facial Surgery, Geneva, Switzerland

  3. 3

    Geneva University Hospitals, Division of Bone Diseases, Geneva, Switzerland

  4. 4

    Geneva University Hospitals, Division of Anaesthesiology, Department APSIC, Genève 14, Switzerland

  5. 5

    Geneva University Hospitals, Division of Clinical Pharmacology and Toxicology, Geneva, Switzerland

*Nicole B Vogt-Ferrier, Unité de Gérontopharmacologie Clinique, Hôpitaux Universitaires de Genève, 3, Chemin Pont-Bochet, Thônex, CH-1226, Switzerland. Nicole-B.Vogt-Ferrier@hcuge.ch.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 14 APR 2010

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To determine the efficacy, safety and adverse events of any intervention (surgical or not) aimed at treating osteonecrosis of the jaws associated with bisphosphonate therapy.

Our purpose is to offer an extensive review of the published literature, including observational studies and case series or thoroughly described case reports, with an assessment of the quality of the data. We aim to review these non-randomised studies to draw conclusions for research and not for clinical management, unless we were to find a large cohort study showing a large clinical effect on an objective outcome.