Intervention Protocol
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis in patients with colorectal cancer
Editorial Group: Cochrane Colorectal Cancer Group
Published Online: 14 APR 2010
Assessed as up-to-date: 16 MAR 2010
DOI: 10.1002/14651858.CD008479
Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Database Title
Additional Information
How to Cite
Verzijden JCM, Klaver YLB, de Hingh IHJT, Bleichrodt RP. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis in patients with colorectal cancer (Protocol). Cochrane Database of Systematic Reviews 2010, Issue 4. Art. No.: CD008479. DOI: 10.1002/14651858.CD008479.
Publication History
- Publication Status: New
- Published Online: 14 APR 2010
- Abstract
- Article
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Abstract
This is the protocol for a review and there is no abstract. The objectives are as follows:
Primary aim:
To determine whether the performance of cytoreductive surgery and HIPEC results in a survival advantage in patients with PC from colorectal origin when compared to standard palliative treatment.
Secondary aim:
To determine morbidity and mortality associated with cytoreductive surgery and HIPEC for peritoneal carcinomatosis from colorectal origin.
Tertiairy aim:
To evaluate different study designs used to investigate the management of peritoneal carcinomatosis, and to identify the limitations in these study designs. This information will be discussed in the “implications for research” section.