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Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis in patients with colorectal cancer

  • Protocol
  • Intervention



This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary aim:

To determine whether the performance of cytoreductive surgery and HIPEC results in a survival advantage in patients with PC from colorectal origin when compared to standard palliative treatment. 

Secondary aim:

To determine morbidity and mortality associated with cytoreductive surgery and HIPEC for peritoneal carcinomatosis from colorectal origin. 

Tertiairy aim:

To evaluate different study designs used to investigate the management of peritoneal carcinomatosis, and to identify the limitations in these study designs. This information will be discussed in the “implications for research” section.