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Interventions for the prevention of postoperative ear discharge after insertion of ventilation tubes (grommets) in children

  1. Mohammed Iqbal Syed1,
  2. Sharon Suller2,
  3. George G Browning2,
  4. Michael A Akeroyd2,*

Editorial Group: Cochrane Ear, Nose and Throat Disorders Group

Published Online: 30 APR 2013

Assessed as up-to-date: 3 JUL 2012

DOI: 10.1002/14651858.CD008512.pub2


How to Cite

Syed MI, Suller S, Browning GG, Akeroyd MA. Interventions for the prevention of postoperative ear discharge after insertion of ventilation tubes (grommets) in children. Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD008512. DOI: 10.1002/14651858.CD008512.pub2.

Author Information

  1. 1

    St John's Hospital at Howden, Livingston, UK

  2. 2

    Glasgow Royal Infirmary, MRC Institute of Hearing Research (Scottish Section), Glasgow, UK

*Michael A Akeroyd, MRC Institute of Hearing Research (Scottish Section), Glasgow Royal Infirmary, Queen Elizabeth Building, 16 Alexandra Parade, Glasgow, G31 2ER, UK. maa@ihr.gla.ac.uk.

Publication History

  1. Publication Status: New
  2. Published Online: 30 APR 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Individual ratings of the 15 trials for each category of risk of bias.
[Figure 3]
Figure 3. Distribution of classifications for each risk of bias category. All 15 trials are included.
[Figure 4]
Figure 4. Forest plot of  Analysis 4.3: Control versus single application of topical antibiotics/steroids, assessed at up to 4 to 6 weeks (by ear/low risk of bias RCTs). See section A.4 of Effects of interventions for more information.
[Figure 5]
Figure 5. Forest plot of  Analysis 13.1: Prolonged application of topical antibiotics versus topical antibiotics/steroids, assessed at up to 2 to 3 weeks (by ear/low risk of bias RCTs). See section A.13 of Effects of interventions for more information.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Control versus irrigation of the middle ear, Outcome 1 Single application/assessment at up to 2 weeks/by child (low risk of bias).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Control versus antiseptic irrigation of middle ear, Outcome 1 Single application/assessment at up to 1 week/by child (high risk of bias).
[Analysis 3.1]
Analysis 3.1. Comparison 3 Control versus topical antibiotics, Outcome 1 Single application/assessment at up to 2 weeks/by ear (high risk of bias).
[Analysis 3.2]
Analysis 3.2. Comparison 3 Control versus topical antibiotics, Outcome 2 Prolonged application/assessment at up to 2 weeks/by ear (high risk of bias).
[Analysis 3.3]
Analysis 3.3. Comparison 3 Control versus topical antibiotics, Outcome 3 Prolonged application/assessment at up to 2 weeks/by child.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Control versus topical antibiotics/steroids, Outcome 1 Single application/assessment at up to 2 weeks/by ear.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Control versus topical antibiotics/steroids, Outcome 2 Prolonged application/assessment at up to 2 weeks/by child or ear.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Control versus topical antibiotics/steroids, Outcome 3 Single application/assessment at up to 4 to 6 weeks/by ear (low risk of bias).
[Analysis 5.1]
Analysis 5.1. Comparison 5 Control versus topical antibiotics or topical antibiotics/steroids, Outcome 1 Single application/assessed at up to 2 weeks/by child or ear (high risk of bias).
[Analysis 6.1]
Analysis 6.1. Comparison 6 Control versus oral antibiotics, Outcome 1 Prolonged application/assessment at up to 2 weeks/by child (high risk of bias).
[Analysis 7.1]
Analysis 7.1. Comparison 7 Control versus oral antibacterial agents/steroids, Outcome 1 Prolonged application/assessment at up to 2 weeks/by child (low risk of bias).
[Analysis 7.2]
Analysis 7.2. Comparison 7 Control versus oral antibacterial agents/steroids, Outcome 2 Prolonged application/assessment at 3 weeks/by child (low risk of bias).
[Analysis 8.1]
Analysis 8.1. Comparison 8 Control versus combination of topical antibiotics and antiseptic/saline preparation, Outcome 1 Prolonged application/assessment at up to 1 week/by child (high risk of bias).
[Analysis 9.1]
Analysis 9.1. Comparison 9 Irrigation of middle ear versus topical antibiotics, Outcome 1 Prolonged application/assessment at up to 2 weeks/by child (high risk of bias).
[Analysis 10.1]
Analysis 10.1. Comparison 10 Irrigation of middle ear versus oral antibiotics, Outcome 1 Prolonged application/assessment up to 2 weeks/by child (high risk of bias).
[Analysis 11.1]
Analysis 11.1. Comparison 11 Antiseptic/saline preparation versus topical antibiotics, Outcome 1 Prolonged application/assessment at up to 1 week/by child.
[Analysis 12.1]
Analysis 12.1. Comparison 12 Antiseptic/saline preparation versus combination of topical antibiotics and antiseptic/saline preparation, Outcome 1 Single and prolonged application/assessment up to 1 week/by child (high risk of bias).
[Analysis 13.1]
Analysis 13.1. Comparison 13 Topical antibiotics versus topical antibiotics/steroids, Outcome 1 Prolonged application/assessment at up to 2 to 3 weeks/by ear (high risk of bias).
[Analysis 14.1]
Analysis 14.1. Comparison 14 Topical antibiotics versus combination of topical antibiotics and antiseptic preparation, Outcome 1 Single and prolonged application/assessment at up to 1 week/by child (high risk of bias).
[Analysis 15.1]
Analysis 15.1. Comparison 15 Topical antibiotics versus oral antibiotics, Outcome 1 Prolonged application/assessment at up to 2 weeks/by child (high risk of bias).
[Analysis 16.1]
Analysis 16.1. Comparison 16 Single versus prolonged application of topical antibiotics, Outcome 1 Gentamicin/assessment at up to 2 weeks/by child (high risk of bias).
[Analysis 16.2]
Analysis 16.2. Comparison 16 Single versus prolonged application of topical antibiotics, Outcome 2 Ciprofloxacin/assessment at up to 2 weeks/by ear (high risk of bias).