Combination chemotherapy versus single agent chemotherapy during preoperative chemoradiation for resectable rectal cancer
Editorial Group: Cochrane Colorectal Cancer Group
Published Online: 16 JUN 2010
Assessed as up-to-date: 22 MAR 2010
Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
How to Cite
Resende HM, Lustosa SAS, Menandro V, Novaes J, Matos D. Combination chemotherapy versus single agent chemotherapy during preoperative chemoradiation for resectable rectal cancer (Protocol). Cochrane Database of Systematic Reviews 2010, Issue 6. Art. No.: CD008531. DOI: 10.1002/14651858.CD008531.
- Publication Status: Edited (no change to conclusions)
- Published Online: 16 JUN 2010
This is the protocol for a review and there is no abstract. The objectives are as follows:
To compare patients outcomes (including overall survival, disease free survival and toxicity) between two chemotherapy schedules in stage II and III rectal cancer given as part of pre-operative chemoradiation. The control comparison will be radiotherapy and a fluoropyrimidine, and the intervention will be radiotherapy, fluoropyrimidine and an additional drug(s), excluding biological agents.