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Sumatriptan plus naproxen for acute migraine attacks in adults

  1. Simon Law1,
  2. Sheena Derry2,*,
  3. R Andrew Moore2

Editorial Group: Cochrane Pain, Palliative and Supportive Care Group

Published Online: 21 OCT 2013

Assessed as up-to-date: 3 OCT 2013

DOI: 10.1002/14651858.CD008541.pub2


How to Cite

Law S, Derry S, Moore RA. Sumatriptan plus naproxen for acute migraine attacks in adults. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD008541. DOI: 10.1002/14651858.CD008541.pub2.

Author Information

  1. 1

    Gloucester Hospitals NHS Foundation Trust, Department of Anaesthetics, Gloucestershire, UK

  2. 2

    University of Oxford, Pain Research and Nuffield Department of Clinical Neurosciences, Oxford, Oxfordshire, UK

*Sheena Derry, Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, OX3 7LE, UK. sheena.derry@ndcn.ox.ac.uk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 21 OCT 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Brandes 2007 Study 1 {published data only}
  • Brandes JL, Kudrow D, Stark SR, O'Carroll CP, Adelman JU, O'Donnell FJ, et al. Sumatriptan-naproxen for acute treatment of migraine: a randomized trial. JAMA 2007;297(13):1443-54. [DOI: 10.1001/jama.297.13.1443]
  • Landy S, DeRossett SE, Rapoport A, Rothrock J, Ames MH, McDonald SA, et al. Two double-blind, multicentre, randomized, placebo-controlled, single-dose studies of sumatriptan/naproxen sodium in the acute treatment of migraine: function, productivity and satisfaction outcomes. Medscape General Medicine 2007;9(2):53.
Brandes 2007 Study 2 {published data only}
  • Brandes JL, Kudrow D, Stark SR, O'Carroll CP, Adelman JU, O'Donnell FJ, et al. Sumatriptan-naproxen for acute treatment of migraine: a randomized trial. JAMA 2007;297(13):1443-54. [DOI: 10.1001/jama.297.13.1443]
  • Landy S, DeRossett SE, Rapoport A, Rothrock J, Ames MH, McDonald SA, et al. Two double-blind, multicentre, randomized, placebo-controlled, single-dose studies of sumatriptan/naproxen sodium in the acute treatment of migraine: function, productivity and satisfaction outcomes. Medscape General Medicine 2007;9(2):53.
Lipton 2009 Study 1 {published data only}
Lipton 2009 Study 2 {published data only}
Mannix 2009 Study 1 {published data only}
Mannix 2009 Study 2 {published data only}
Mathew 2009 Study 1 {published data only}
Mathew 2009 Study 2 {published data only}
Silberstein 2008 Study 1 {published data only}
  • Silberstein SD, Mannix LK, Goldstein J, Couch JR, Byrd SC, Ames MH, et al. Multimechanistic (sumatriptan-naproxen) early intervention for the acute treatment of migraine. Neurology 2008;71(2):114-21. [DOI: 10.1212/01.wnl.0000316800.22949.20]
  • Taylor FR, Heiring JO, Messina E, Braverman-Panza J, Ames MH, Byrd SC, et al. Sumatriptan/naproxen sodium as early intervention for migraine: effects on functional ability, productivity, and satisfaction in 2 randomized controlled trials. Journal of Clinical Outcomes Management 2007;14(4):195-204.
Silberstein 2008 Study 2 {published data only}
  • Silberstein SD, Mannix LK, Goldstein J, Couch JR, Byrd SC, Ames MH, et al. Multimechanistic (sumatriptan-naproxen) early intervention for the acute treatment of migraine. Neurology 2008;71(2):114-21. [DOI: 10.1212/01.wnl.0000316800.22949.20]
  • Taylor FR, Heiring JO, Messina E, Braverman-Panza J, Ames MH, Byrd SC, et al. Sumatriptan/naproxen sodium as early intervention for migraine: effects on functional ability, productivity, and satisfaction in 2 randomized controlled trials. Journal of Clinical Outcomes Management 2007;14(4):195-204.
Smith 2005 {published data only}
TRX109011/13 {unpublished data only}
  • A randomized, double-blind, double-dummy, placebo-controlled, crossover study to evaluate the efficacy of TREXIMET (sumatriptan + naproxen sodium) versus Butalbital-Containing Combination Medications (BCM) for the acute treatment of migraine when administered during the moderate-severe pain phase of the migraine (pooled data), 2010. download.gsk-clinicalstudyregister.com/files/21144.pdf (accessed 23 September 2013).
  • Derosier F, Sheftell F, Silberstein S, Cady R, Ruoff G, Krishen A, et al. Sumatriptan-naproxen and butalbital: a double-blind, placebo-controlled crossover study. Headache 2012;52(4):530-43. [DOI: 10.1111/j.1526-4610.2011.02039.x]

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Krymchantowski 2000 {published data only}
Landy 2009 {published data only}
  • Landy S, White J, Lener SE, McDonald SA. Fixed-dose sumatriptan/naproxen sodium compared with each monotherapy utilizing the novel composite endpoint of sustained pain-free/no adverse events. Therapeutic Advances in Neurological Disorders 2009;2:135. [DOI: 10.1177/1756285609102769]
Smith 2007 {published data only}
TRX107563 {unpublished data only}
  • Glazo Smith Kline study register. A randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and tolerability of TREXIMET (sumatriptan 85mg and naproxen sodium 500mg) for a single moderate or severe headache in adults diagnosed with probable migraine without aura. www.clinicaltrials.gov/ct2/show/NCT00387881 (accessed 23 September 2013).
White 2011 {published data only}
Winner 2007 {published data only}
  • Winner P, Cady RK, Ruoff GE, Frishberg BM, Alexander WJ, Zhang Y, et al. Twelve month tolerability and safety of sumatriptan-naproxen sodium for the treatment of acute migraine. Mayo Clinic Proceedings 2007;82(1):61-8.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Ayzenberg 2012
Bandolier 2000
  • Bandolier. Naproxen for acute migraine, 2000. www.medicine.ox.ac.uk/bandolier/booth/Migraine/NapORacu.html (23 September 2013).
Bigal 2008
Bloudek 2012
Burstein 2001
Buse 2011
Collins 1997
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Derry 2009
  • Derry C, Derry S, Moore RA, McQuay HJ. Single dose oral naproxen and naproxen sodium for acute postoperative pain in adults. Cochrane Database of Systematic Reviews 2009, Issue 1. [DOI: 10.1002/14651858.CD004234.pub3]
Derry 2012
  • Derry CJ, Derry S, Moore RA. Sumatriptan (oral route of administration) for acute migraine attacks in adults. Cochrane Database of Systematic Reviews 2012, Issue 2. [DOI: 10.1002/14651858.CD008615.pub2]
Diamond 2007
  • Diamond S, Bigal ME, Silberstein S, Loder E, Reed M, Lipton RB. Patterns of diagnosis and acute and preventive treatment for migraine in the United States: results from the American Migraine Prevalence and Prevention study. Headache 2007;47(3):355-63.
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Jakubowski 2007
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Lipton 2007
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Moore 2008
  • Moore RA, Barden J, Derry S, McQuay HJ. Managing potential publication bias. In: McQuay HJ, Kalso E, Moore RA editor(s). Systematic Reviews in Pain Research: Methodology Refined. Seattle: IASP Press, 2008:15-24. [ISBN: 978-0-931092-69-5]
Moore 2010a
  • Moore RA, Moore OA, Derry S, Peloso PM, Gammaitoni AR, Wang H. Responder analysis for pain relief and numbers needed to treat in a meta-analysis of etoricoxib osteoarthritis trials: bridging a gap between clinical trials and clinical practice. Annals of the Rheumatic Diseases 2010;69(2):374-9. [DOI: 10.1136/ard.2009.107805]
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Steiner 2013
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Suthisisang 2011
  • Suthisisang CC, Poolsup N, Suksomboon N. Efficacy and safety of sumatriptan plus naproxen sodium in the acute treatment of migraine: systematic review and meta-analysis of randomized controlled trials. Internet Journal of Pain, Symptom Control and Palliative Care 2011;8:2. [DOI: 10.5580/6a2]
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