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Ultrasound and shockwave therapy for acute fractures in adults

  1. Xavier L Griffin*,
  2. Nick Smith,
  3. Nick Parsons,
  4. Matthew L Costa

Editorial Group: Cochrane Bone, Joint and Muscle Trauma Group

Published Online: 15 FEB 2012

Assessed as up-to-date: 12 DEC 2011

DOI: 10.1002/14651858.CD008579.pub2


How to Cite

Griffin XL, Smith N, Parsons N, Costa ML. Ultrasound and shockwave therapy for acute fractures in adults. Cochrane Database of Systematic Reviews 2012, Issue 2. Art. No.: CD008579. DOI: 10.1002/14651858.CD008579.pub2.

Author Information

  1. University of Warwick, Warwick Orthopaedics, Warwick Medical School, Coventry, UK

*Xavier L Griffin, Warwick Orthopaedics, Warwick Medical School, University of Warwick, Clinical Sciences Building, Clifford Bridge Road, Coventry, CV2 2DX, UK. x.griffin@warwick.ac.uk. xgriffin@mac.com.

Publication History

  1. Publication Status: New
  2. Published Online: 15 FEB 2012

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This is not the most recent version of the article. View current version (23 JUN 2014)

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Emami 1999 {published data only}
Handolin 2005 {published data only (unpublished sought but not used)}
  • Handolin L, Kiljunen V, Arnala I, Kiuru MJ, Pajarinen J, Partio EK, et al. No long-term effects of ultrasound therapy on bioabsorbable screw-fixed lateral malleolar fracture. Scandinavian Journal of Surgery 2005;94(3):239-42.
  • Handolin L, Kiljunen V, Arnala I, Pajarinen J, Partio EK, Rokkanen P. The effect of low intensity ultrasound and bioabsorbable self-reinforced poly-L-lactide screw fixation on bone in lateral malleolar fractures. Archives of Orthopaedic and Trauma Surgery 2005;125(5):317-21.
Handolin 2005a {published data only (unpublished sought but not used)}
  • Handolin L, Kiljunen V, Arnala I, Kiuru MJ, Pajarinen J, Partio EK, et al. Effect of ultrasound therapy on bone healing of lateral malleolar fractures of the ankle joint fixed with bioabsorbable screws. Journal of Orthopaedic Science 2005;10(4):391-5.
Heckman 1994 {published and unpublished data}
  • Cook S, Ryaby JP, Heckmann JD, Kristiansen TK. Low-intensity pulsed ultrasound accelerates tibia and distal radius fracture healing in smokers. Hefte zur der Unfallchirurg 1996;262:336.
  • Cook SD, Ryaby JP, McCabe J, Frey JJ, Heckman JD, Kristiansen TK. Acceleration of tibia and distal radius fracture healing in patients who smoke. Clinical Orthopaedics & Related Research 1997;(337):198-207.
  • Cook SD, Ryaby JP, McCabe J, Frey JJ, Heckman JD, Kristiansen TK. Low intensity pulsed ultrasound accelerates tibia and distal radius fracture healing in smokers [abstract]. Orthopaedic Transactions 1996;20(1):56.
  • Heckman JD. Personal communication September 2 2010.
  • Heckman JD, Ryaby JP, McCabe J, Frey JJ, Kilcoyne RF. Acceleration of tibial fracture-healing by non-invasive, low-intensity pulsed ultrasound. Journal of Bone and Joint Surgery - American Volume 1994;76(1):26-34.
Kristiansen 1997 {published and unpublished data}
  • Cook S, Ryaby JP, Heckmann HD, Kristiansen TK. Low-intensity pulsed ultrasound accelerates tibia and distal radius fracture healing in smokers. Hefte zur der Unfallchirurg 1996;262:336.
  • Cook SD, Ryaby JP, McCabe J, Frey JJ, Heckman JD, Kristiansen TK. Acceleration of tibia and distal radius fracture healing in patients who smoke. Clinical Orthopaedics & Related Research 1997;(337):198-207.
  • Cook SD, Ryaby JP, McCabe J, Frey JJ, Heckman JD, Kristiansen TK. Low intensity pulsed ultrasound accelerates tibia and distal radius fracture healing in smokers [abstract]. Orthopaedic Transactions 1996;20(1):56.
  • Kristiansen TK, Ryaby JP, McCabe J, Frey J. Controlling loss of reduction in distal radius fractures in an randomized, double-blind study using low-intensity ultrasound. Hefte zur der Unfallchirurg. 1996; Vol. 262:369.
  • Kristiansen TK, Ryaby JP, McCabe J, Frey J. Controlling loss of reduction in distal radius fractures with low intensity pulsed ultrasound [abstract]. Orthopaedic Transactions 1997;21(1):141.
  • Kristiansen TK, Ryaby JP, McCabe J, Frey JJ, Roe LR. Accelerated healing of distal radial fractures with the use of specific, low-intensity ultrasound: A multicenter, prospective, randomized, double- blind, placebo-controlled study. Journal of Bone and Joint Surgery - American Volume 1997;79(7):961-73.
  • McCabe J. Personal communication September 22 2010.
Leung 2004 {published data only}
  • Leung KS, Lee WS, Tsui HF, Liu PPL, Cheung WH. Complex tibial fracture outcomes following treatment with low-intensity pulsed ultrasound. Ultrasound in Medicine and Biology 2004;30(3):389-95.
Lubbert 2008 {published and unpublished data}
  • Lubbert PH. Personal communication November 7 2010.
  • Lubbert PHW, van der Rijt RHH, Hoorntje LE, van der Werken C. Low-intensity pulsed ultrasound (LIPUS) in fresh clavicle fractures: A multi-centre double blind randomised controlled trial. Injury 2008;39(12):1444-52.
Mayr 2000 {published data only}
  • Mayr E. Accelerated healing of scaphoid fracture - a randomized study [abstract]. Journal of Bone and Joint Surgery - British Volume 1999;81 Suppl 2:206.
  • Mayr E, Rudzki M, Borchardt B, Ruter A. Accelerated healing of scaphoid fractures - A randomized study [abstract]. Journal of Orthopaedic Trauma 1999;13(4):310.
  • Mayr E, Rudzki M-M, Rudzki M, Borchardt B, Hausser H, Ruter A. Does Pulsed Low-Intensity Ultrasound Accelerate Healing of Scaphoid Fractures? [Beschleunigt niedrig intensive, gepulster Ultraschall die Heilung von Skaphoidfrakturen?]. Handchirurgie Mikrochirurgie Plastische Chirurgie 2000;32(2):115-22.
Rue 2004 {published data only}
  • Rue JP, Armstrong DW 3rd, Frassica FJ, Deafenbaugh M, Wilckens JH. The effect of pulsed ultrasound in the treatment of tibial stress fractures. Orthopedics 2004;27(11):1192-5.
Strauss 1999 {published data only (unpublished sought but not used)}
  • Strauss E, Ryaby JP, McCabe J. Treatment of Jones' fractures of the foot with adjunctive use of low-pulsed ultrasound stimulation. Journal of Orthopaedic Trauma 1999;13(4):310.
Wang 2007 {published data only}
  • Liu HC, Fu TH. Effects of shockwave on acute high-energy fractures of the femur and tibia [abstract]. American Academy of Orthopaedic Surgeons Annual Meeting. Febuary 2007.
  • Wang CJ, Liu HC, Fu TH. The effects of extracorporeal shockwave on acute high-energy long bone fractures of the lower extremity. Archives of Orthopaedic and Trauma Surgery 2007;127(2):137-42.
Yadav 2008 {published data only}
  • Yadav YK, Salgotra KR, Banerjee A. Role of ultrasound therapy in the healing of tibial stress fractures. Medical Journal Armed Forces India 2008;64(3):234-6.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Basso 1998 {published data only}
  • Basso O, Pike JM. The effect of low frequency, long-wave ultrasound therapy on joint mobility and rehabilitation after wrist fracture. Journal of Hand Surgery - British Volume 1998;23(1):136-9.
Busse 2005 {published data only}
  • Busse JW, Bhandari M, Sprague S, Johnson-Masotti AP, Gafni A. An economic analysis of management strategies for closed and open grade I tibial shaft fractures. Acta Orthopaedica 2005;76(5):705-12.
Heckman 1997 {published data only}
  • Heckman JD, Sarasohn-Kahn J. The economics of treating tibia fractures: The cost of delayed unions. Bulletin of The Hospital for Joint Dieases 1997;56(1):63-72.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
ISRCTN90844675 {unpublished data only}
  • Seifert J. Pulsed ultrasound to speed-up healing after intramedullary nailing of tibia fractures (PUSH-IT). http://controlled-trials.com/ISRCTN90844675/ISRCTN90844675 (accessed 9 December 2011).
TRUST (Pilot) {unpublished data only}
  • Bhandari M, Busse J, Guyatt G. Trial to re-evaluate ultrasound in the treatment of tibial fractures (TRUST). http://www.controlled-trials.com/ISRCTN98682811 (accessed 14 June 2011).
  • Busse J. personal communication 20 December 2011.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
TRUST (Full) {unpublished data only}
  • Bhandari M. Trial to re-evaluate ultrasound in the treatment of tibial fractures (TRUST). http://www.clinicaltrials.gov/ct2/show/NCT00667849 (accessed 7 December 2011).

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Aaron 2004
  • Aaron RK, Ciombor DM, Simon BJ. Treatment of nonunions with electric and electromagnetic fields. Clinical Orthopaedics & Related Research 2004;(419):21-9. [PUBMED: 15021127]
Boutron 2008
  • Boutron I, Moher D, Altman DG, Schulz KF, Ravaud P, CONSORT Group. Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Annals of Internal Medicine 2008;148(4):295-309.
Busse 2009
  • Busse JW, Kaur J, Mollon B, Bhandari M, Tornetta P 3rd, Schunemann HJ, et al. Low intensity pulsed ultrasonography for fractures: systematic review of randomised controlled trials. BMJ 2009;338:b351.
Busse 2011
  • Busse J. personal communication 20 December 2011.
Cook 1997
  • Cook SD, Ryaby JP, McCabe J, Frey JJ, Heckman JD, Kristiansen TK. Acceleration of tibia and distal radius fracture healing in patients who smoke. Clinical Orthopaedics & Related Research 1997;(337):198-207.
Einhorn 1995
Griffin 2008
  • Griffin XL, Costello I, Costa ML. The role of low intensity pulsed ultrasound therapy in the management of acute fractures: a systematic review. Journal of Trauma-Injury Infection & Critical Care 2008;65(6):1446-52. [PUBMED: 19077640]
Hadjiargyrou 1998
  • Hadjiargyrou M, McLeod K, Ryaby JP, Rubin C. Enhancement of fracture healing by low intensity ultrasound. Clinical Orthopaedics & Related Research 1998;(355 Suppl):S216-29. [PUBMED: 9917641]
Handolin 2005b
  • Handolin L, Kiljunen V, Arnala I, Kiuru MJ, Pajarinen J, Partio EK, et al. No long-term effects of ultrasound therapy on bioabsorbable screw-fixed lateral malleolar fracture. Scandinavian Journal of Surgery 2005;94(3):239-42.
Higgins 2003
Higgins 2008
  • Higgins JPT, Altman DG. Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions. Chichester: John Wiley & Sons, 2008.
Lefebvre 2009
  • Lefebvre C, Manheimer E, Glanville J. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.2 [updated September 2009]. The Cochrane Collaboration, 2009. Available from www.cochrane-handbook.org.
Reher 1997
  • Reher P, Elbeshir el-NI, Harvey W, Meghji S, Harris M. The stimulation of bone formation in vitro by therapeutic ultrasound. Ultrasound in Medicine & Biology 1997;23(8):1251-8. [PUBMED: 9372573]
Victoria 2009
Wang 1994