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Automated weaning and spontaneous breathing trial systems versus non-automated weaning strategies for discontinuation time in invasively ventilated postoperative adults

  1. Karen EA Burns1,*,
  2. Francois Lellouche2,
  3. Martin R Lessard3,
  4. Jan O Friedrich4

Editorial Group: Cochrane Anaesthesia, Critical and Emergency Care Group

Published Online: 13 FEB 2014

Assessed as up-to-date: 2 MAY 2012

DOI: 10.1002/14651858.CD008639.pub2


How to Cite

Burns KEA, Lellouche F, Lessard MR, Friedrich JO. Automated weaning and spontaneous breathing trial systems versus non-automated weaning strategies for discontinuation time in invasively ventilated postoperative adults. Cochrane Database of Systematic Reviews 2014, Issue 2. Art. No.: CD008639. DOI: 10.1002/14651858.CD008639.pub2.

Author Information

  1. 1

    Keenan Research Centre/Li Ka Shing Knowledge Institute, Interdepartmental Division of Critical Care and the University of Toronto, Toronto, Ontario, Canada

  2. 2

    Hopital Laval, Intensive Care Department, Quebec City, Quebec, Canada

  3. 3

    Université Laval, Department of Anesthesia and Critical care, CHU de Québec, Division of Adult Intensive Care, Department of Anesthesiology, Quebec City, Quebec, Canada

  4. 4

    University of Toronto and Keenan Research Centre/Li Ka Shing Knowledge Institute, Critical Care and Medicine Departments, St. Michael's Hospital, Interdepartmental Division of Critical Care, Toronto, Ontario, Canada

*Karen EA Burns, Interdepartmental Division of Critical Care and the University of Toronto, Keenan Research Centre/Li Ka Shing Knowledge Institute, St Michael's Hospital, 30 Bond Street, Rm 4-045 Queen Wing, Toronto, Ontario, M5B 1WB, Canada. BurnsK@smh.ca. burnske2@hotmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 13 FEB 2014

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Discontinuation time (randomization to extubation), Outcome 1 Discontinuation time (randomization to extubation).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Time to successful extubation, Outcome 1 Time to successful extubation.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Time to first spontaneous breathing trial, Outcome 1 Time to first spontaneous breathing trial.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Time to first successful spontaneous breathing trial, Outcome 1 Time to first successful spontaneous breathing trial.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Most protracted measure of mortality, Outcome 1 Most protracted measure of mortality.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Total duration of mechanical ventilation, Outcome 1 Total duration of mechanical ventilation.
[Analysis 7.1]
Analysis 7.1. Comparison 7 Intensive care unit length of stay, Outcome 1 Intensive care unit length of stay.
[Analysis 8.1]
Analysis 8.1. Comparison 8 Use of non-invasive ventilation following extubation, Outcome 1 Use of noninvasive ventilation following extubation.
[Analysis 9.1]
Analysis 9.1. Comparison 9 Adverse event: reintubation, Outcome 1 Adverse event: reintubation.
[Analysis 10.1]
Analysis 10.1. Comparison 10 Prolonged mechanical ventilation (> 14 days), Outcome 1 Prolonged mechanical ventilation (> 14 days).
[Analysis 11.1]
Analysis 11.1. Comparison 11 Prolonged mechanical ventilation (> 21 days), Outcome 1 Prolonged mechanical ventilation (> 21 days).
[Analysis 12.1]
Analysis 12.1. Comparison 12 Adverse event: tracheostomy, Outcome 1 Adverse event: tracheostomy.
[Analysis 13.1]
Analysis 13.1. Comparison 13 Adverse event: self-extubation, Outcome 1 Adverse event: self-extubation.
[Analysis 14.1]
Analysis 14.1. Comparison 14 Hospital length of stay, Outcome 1 Hospital length of stay.