Diagnostic Test Accuracy Review

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Red flags to screen for malignancy in patients with low-back pain

  1. Nicholas Henschke1,*,
  2. Christopher G. Maher2,
  3. Raymond WJG Ostelo3,
  4. Henrica CW de Vet4,
  5. Petra Macaskill5,
  6. Les Irwig6

Editorial Group: Cochrane Back and Neck Group

Published Online: 28 FEB 2013

DOI: 10.1002/14651858.CD008686.pub2


How to Cite

Henschke N, Maher CG, Ostelo RWJG, de Vet HCW, Macaskill P, Irwig L. Red flags to screen for malignancy in patients with low-back pain. Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD008686. DOI: 10.1002/14651858.CD008686.pub2.

Author Information

  1. 1

    University of Heidelberg, Institute of Public Health, Heidelberg, Germany

  2. 2

    University of Sydney, The George Institute for Global Health, Sydney, NSW, Australia

  3. 3

    VU University, Department of Health Sciences, EMGO Institute for Health and Care Research, Amsterdam, Netherlands

  4. 4

    VU University Medical Center, Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, Amsterdam, Netherlands

  5. 5

    School of Public Health, Screening and Test Evaluation Program (STEP), Sydney, NSW, Australia

  6. 6

    University of Sydney, School of Public Health, Sydney, NSW, Australia

*Nicholas Henschke, Institute of Public Health, University of Heidelberg, Im Neuenheimer Feld 324, Heidelberg, 69120, Germany. nhenschke@georgeinstitute.org.au.

Publication History

  1. Publication Status: New
  2. Published Online: 28 FEB 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Deyo 1986 {published data only}
Deyo 1988 {published data only}
Donner-Banzhoff 2006 {published data only}
  • Donner-Banzhoff N, Roth T, Sönnichsen AC, Luckmann J, Leonhardt C, Chenot JF, et al. Evaluating the accuracy of a simple heuristic to identify serious causes of low back pain. Family Practice 2006;23(6):682-6.
Frazier 1989 {published data only}
  • Frazier LM, Carey TS, Lyles MF, Khayrallah MA, McGaghie WC. Selective criteria may increase lumbosacral spine roentgenogram use in acute low-back pain. Archives of Internal Medicine 1989;149:47-50.
Henschke 2009 {published data only}
  • Henschke N, Maher CG, Refshauge KM, Herbert RD, Cumming RG, Bleasel J, et al. Prevalence of and screening for serious spinal pathology in patients presenting to primary care settings with acute low back pain. Arthritis & Rheumatism 2009;60(10):3072-80.
Jacobson 1997 {published data only}
Khoo 2003 {published data only}
  • Khoo LAL, Heron C, Patel U, Given-Wilson R, Grundy A, Khaw KT, et al. The diagnostic contribution of the frontal lumbar spine radiograph in community referred low back pain - a prospective study of 1030 patients. Clinical Radiology 2003;58:606-9.
Reinus 1998 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Börm 2004 {published data only}
Sedonja 1999 {published data only}

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Bigos 1994
  • Bigos SJ, Braen GR, Deyo RA, Hart J, Keller R, Liang M, et al. Acute low back problems in adults. Clinical practice guideline no. 14. Rockville, MD: Agency for Health Care Policy and Research, Public Health Service, U.S. Department of Health and Human Services, 1994.
Bossuyt 2003
  • Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, et al. Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative. Annals of Internal Medicine 2003;138:40-4.
Chou 2007
  • Chou R, Qaseem A, Snow V, Casey D, Cross JT, Shekelle P, et al. Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society. Annals of Internal Medicine 2007;147(7):478-91.
Deeks 2009
  • Deeks JJ, Bossuyt PM, Gatsonis C (editors). Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy Version 1.0.1 [updated March 2009]. The Cochrane Collaboration, 2009. Available from: http://srdta.cochrane.org/.
Deyo 1992
Henschke 2007
Henschke 2010
  • Henschke N, Williams C, Maher CG, van Tulder MW, Koes BW, Macaskill P, et al. Red flags to screen for vertebral fracture in patients presenting with low-back pain. Cochrane Database of Systematic Reviews 2010, Issue 8. [DOI: 10.1002/14651858.CD008643]
Jarvik 2002
Joines 2001
Koes 2006
Koes 2010
  • Koes BW, van Tulder MW, Lin CWC, Macedo LG, McAuley J, Maher C. An updated overview of clinical guidelines for the management of non-specific low back pain in primary care. European Spine Journal 2010;19(12):2075-94.
Loblaw 2005
  • Loblaw DA, Perry J, Chambers A, Laperriere NJ. Systematic review of the diagnosis and management of malignant extradural spinal cord compression: The Cancer Care Ontario Practice Guidelines Initiative’s Neuro-Oncology Disease Site Group. Journal of Clinical Oncology 2005;23(9):2028-37.
Sciubba 2006
Smidt 2006
  • Smidt N, Rutjes AW, van der Windt DA, Ostelo RW, Bossuyt PM, Reitsma JB, et al. The quality of diagnostic accuracy studies since the STARD statement: has it improved?. Neurology 2006;67:792-7.
Underwood 2009
van der Windt 2010
van Tulder 2004
  • van Tulder M, Becker A, Bekkering T, Breen A, Gil del Real MT, Hutchinson A, et al. European guidelines for the management of acute nonspecific low back pain in primary care. European Commission COST B13; Available at www.backpaineurope.org (accessed Dec 8, 2009), 2004.
Waddell 2004
  • Waddell G. The Back Pain Revolution. 2nd Edition. London: Churchill Livingstone, 2004.
Whiting 2003
  • Whiting P, Rutjes A, Reitsma J, Bossuyt P, Kleijnen J. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Medical Research Methodology 2003;3(25):available from http://www.biomedcentral.com/1471-2288/3/25. [DOI: 10.1186/1471-2288-3-25]