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Aloe vera for treating acute and chronic wounds

  1. Anthony D Dat1,*,
  2. Flora Poon1,
  3. Kim BT Pham1,
  4. Jenny Doust2

Editorial Group: Cochrane Wounds Group

Published Online: 15 FEB 2012

Assessed as up-to-date: 9 SEP 2011

DOI: 10.1002/14651858.CD008762.pub2


How to Cite

Dat AD, Poon F, Pham KBT, Doust J. Aloe vera for treating acute and chronic wounds. Cochrane Database of Systematic Reviews 2012, Issue 2. Art. No.: CD008762. DOI: 10.1002/14651858.CD008762.pub2.

Author Information

  1. 1

    Bond University, Faculty of Health Sciences and Medicine, Gold Coast, Queensland, Australia

  2. 2

    Bond University, Centre for Research in Evidence Based Practice, Gold Coast, Queensland, Australia

*Anthony D Dat, Faculty of Health Sciences and Medicine, Bond University, 103 Pioneer Crescent, Gold Coast, Queensland, 4070, Australia. adat@student.bond.edu.au. anthony_dat@hotmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 15 FEB 2012

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Akhtar 1996 {published data only}
  • Akhtar M, Hatwar S. Efficacy of Aloe vera extract cream in management of burn wound. Journal of Clinical Epidemiology 1996;49(Suppl 1):24.
Eshghi 2010 {published data only}
  • Eshghi F, Hosseinimehr S, Hahmani N, Khademloo M, Norozi M, Hojati O. Effects of Aloe vera cream on posthemorrhoidectomy pain and wound healing: results of a randomised, blind, placebo-control study. Journal of Alternative and Complementary Medicine 2010;16(6):647-50.
Khorasani 2009 {published data only}
  • Khorasani G, Hosseinmehr S, Azadbakht M, Zamani A, Mahdavi M. Aloe versus silver sulfadiazaine creams for second-degree burns: a randomised controlled study. Surgery Today 2009;39(7):587-91.
Phillips 1995 {published data only}
  • Phillips T, Ongenae K, Kanj L, Slater-Freedberg J. A randomised study of an Aloe vera derivative gel dressing versus conventional treatment after shave biopsy excisions. Wounds 1995;7(5):200-2.
Schmidt 1991 {published data only}
Thamlikitkul 1991 {published data only}
  • Thamlikitkul V, Bunyapraphatsara N, Riewpaiboon W, Theerapong S, Chantrakul C, et al. Clinical trial of Aloe vera linn. for treatment of minor burns. Siriraj Hospital Gazette 1991;43(5):31-6.
Thomas 1998 {published data only}
  • Thomas D, Goode P, LaMaster K, Tennyson T. Acemannan hydrogel dressing versus saline dressing for pressure ulcers: a randomised, controlled trial. Advances in Wound Care 1998;11(6):273-6.
  • Thomas DR, Goode PS. Acemannan hydrogel versus saline dressings for pressure ulcers: a randomized controlled trial. Journal of Investigative Medicine 1998;46(7):283A.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Fulton 1990 {published data only}
Sun 1994 {published data only (unpublished sought but not used)}
  • Sun J, Chen X, Jin R, Li T, Bian Y. People's liberation army medicine information. Medical Journal of the Chinese Army 1994;8(4):191-2.
Visuthikosol 1995 {published data only}
  • Visuthikosol V, Chowchuen C, Sukwanarat Y, Sriurairatana S, Boonpucknavig V. Effect of Aloe vera gel to healing of burn wound a clinical and histologic study. Journal of the Medical Association of Thailand 1995;78(8):403-9.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Atherton 1998
  • Atherton P. Aloe vera: magic or medicine?. Nursing Standard 1998;12(41):49-54.
Begg 1996
Boudreau 2006
  • Boudreau M, Beland F. An evaluation of the biological and toxicological properties of Aloe Barbadensis (Miller), Aloe Vera. Journal of Environmental Science and Health 2006;Part C 24(1):103-54.
Chithra 1998
Davis 1994
  • Davis R, Di Donato J, Hartman G, Haas R. Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. Journal of the American Podiatric Medical Association 1994;84(2):77-81.
Hamman 2008
Higgins 2011
  • Deeks J, Higgins J, Altman D on behalf of the Cochrane Statistical Methods Group (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Ioannidis 2004
  • Ioannidis J, Evans S, Gotzsche P, O’Neill R, Altman D, Schulz K, et al. Better reporting of harms in randomized trials: an extension of the CONSORT statement. Annals of Internal Medicine 2004;141:781-8.
Kuzuya 2001
  • Kuzuya H, Tamai I, Beppu H, Shimpo K, Chihara T. Determination of aloenin, barbaloin and isobarbaloin in aloe species by micellar electrokinetic chromatography. Journal of Chromatography, Biomedical Sciences and Applications 2001;752(1):91-7.
Lazarus 1994
Lefebvre 2011
  • Lefebvre C, Manheimer E, Glanville J, on behalf of the Cochrane Information Retrieval Methods Group. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Maenthaisong 2007
Mendonca 2009
  • Mendonça F, Passarini Jr J, Esquisatto M, Mendonça J, Franchini C, Dos Santos G. Effects of the application of Aloe vera (L.) and microcurrent on the healing of wounds surgically induced in Wistar rats [Efeitos da aplicação de Aloe vera (L.) e microcorrente no reparo de lesões cirúrgicas induzidasem ratos Wistar]. Acta Cirúrgica Brasileira 2009;24(2):150-5.
SIGN 2010
  • Scottish Intercollegiate Guidelines Network. Search filters. http://www.sign.ac.uk/methodology/filters.html#random (accessed 24 March 2010).
Steenkamp 2007
Takzare 2009
  • Takzare N, Hosseini M, Hasanzadeh G, Mortazavi H, Takzare A, Habibi P. Influence of aloe vera gel on dermal wound healing process in rat. Toxicology Mechanisms and Methods 2009;19(1):73-7.
Tamura 2009
Vogler 1999