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Intervention Protocol

Early versus late administration of amino acids in preterm infants receiving parenteral nutrition

  1. Amit Trivedi1,*,
  2. John KH Sinn2

Editorial Group: Cochrane Neonatal Group

Published Online: 6 OCT 2010

Assessed as up-to-date: 9 AUG 2010

DOI: 10.1002/14651858.CD008771


How to Cite

Trivedi A, Sinn JKH. Early versus late administration of amino acids in preterm infants receiving parenteral nutrition (Protocol). Cochrane Database of Systematic Reviews 2010, Issue 10. Art. No.: CD008771. DOI: 10.1002/14651858.CD008771.

Author Information

  1. 1

    Children's Hospital at Westmead, Grace Centre for Newborn Care, Westmead, NSW, Australia

  2. 2

    Royal North Shore Hospital, Neonatal Unit, St Leonards, New South Wales, Australia

*Amit Trivedi, Grace Centre for Newborn Care, Children's Hospital at Westmead, Westmead, NSW, 2145, Australia. AmitTrivedi@live.com.au.

Publication History

  1. Publication Status: New
  2. Published Online: 6 OCT 2010

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To determine the effect of the initiation of early AAs on growth, development and nitrogen balance in preterm infants receiving parenteral nutrition.

Primary comparison

Early versus late initiation of AAs in isolation or with other components of total parenteral nutrition

Subgroup analyses

1. Studies enrolling premature infants with a gestational age less than 30 weeks versus studies enrolling premature infants with a gestational age 30 or more weeks

2. Birth weight

a. Studies enrolling low birth weight infants (less than 1500 g) versus studies enrolling premature infants of birth weight 1500 g or more

b. Studies enrolling very low birth weight infants (less than 1000 g) versus studies enrolling premature infants of birth weight 1000 g or more

c. High (≧ 2 g/kg/day at commencement) or low (< 2 g/kg/day at commencement) intake

d. Studies initiating AA solutions in isolation versus studies starting AA solutions with other components of total parenteral nutrition