Intervention Review

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Physical exercise training interventions for children and young adults during and after treatment for childhood cancer

  1. Katja I Braam1,
  2. Patrick van der Torre2,†,*,
  3. Tim Takken2,
  4. Margreet A Veening1,
  5. Eline van Dulmen-den Broeder1,
  6. Gertjan JL Kaspers3

Editorial Group: Cochrane Childhood Cancer Group

Published Online: 30 APR 2013

Assessed as up-to-date: 5 MAR 2012

DOI: 10.1002/14651858.CD008796.pub2

How to Cite

Braam KI, van der Torre P, Takken T, Veening MA, van Dulmen-den Broeder E, Kaspers GJL. Physical exercise training interventions for children and young adults during and after treatment for childhood cancer. Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD008796. DOI: 10.1002/14651858.CD008796.pub2.

Author Information

  1. 1

    VU University Medical Center, Department of Pediatrics, Division of Oncology/Hematology, Amsterdam, Netherlands

  2. 2

    Wilhelmina Children's Hospital, University Medical Center Utrecht, Child Development and Exercise Center, Utrecht, Netherlands

  3. 3

    VU University Medical Center, Department of Paediatrics, Division of Paediatric Oncology/Haematology, Amsterdam, Netherlands

  1. Joint first authorship with Katja I. Braam

*Patrick van der Torre, Child Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, PO Box 85090, Utrecht, 3508 AB, Netherlands. p.vandertorre@umcutrecht.nl.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 30 APR 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Cardiorespiratory fitness outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 1 9-minute run-walk test.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Cardiorespiratory fitness outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 2 Timed up-and-down stairs test.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Body composition outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 1 Bone mineral density.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Body composition outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 2 Body mass index.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Flexibility outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 1 Flexiblity.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Muscle endurance/strength outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 1 Knee strength.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Muscle endurance/strength outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 2 Ankle dorsiflexion strength.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Muscle endurance/strength outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 3 Inspiratory breathing muscle strength.
[Analysis 4.4]
Analysis 4.4. Comparison 4 Muscle endurance/strength outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 4 Expiratory breathing muscle strength.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Health-related quality of life outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 1 PedsQL - general.
[Analysis 5.2]
Analysis 5.2. Comparison 5 Health-related quality of life outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 2 PedsQL - cancer.
[Analysis 5.3]
Analysis 5.3. Comparison 5 Health-related quality of life outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 3 Parents PedsQL - general.
[Analysis 5.4]
Analysis 5.4. Comparison 5 Health-related quality of life outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 4 Parents PedsQl - cancer.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Fatigue outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 1 PedsQl - general fatigue.
[Analysis 6.2]
Analysis 6.2. Comparison 6 Fatigue outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 2 PedsQl - sleep/rest fatigue.
[Analysis 6.3]
Analysis 6.3. Comparison 6 Fatigue outcomes after physical exercise training intervention for children and adolescents during or after childhood cancer, Outcome 3 PedsQl - cognitive fatigue.