This is the protocol for a review and there is no abstract. The objectives are as follows:
The aim of this review is to evaluate the effect of exercise on physical fitness (e.g. aerobic capacity, muscle strength or functional performance), of children who received an exercise intervention within the first five years of diagnosis of cancer (during and after treatment), compared to a control group of childhood cancer patients who did not receive an exercise intervention.
In addition, we will determine whether exercise within the first five years of diagnosis has a positive effect on fatigue, anxiety, depression, self-efficacy and health-related quality of life (HrQOL) and will assess how many and which kind of adverse effects of the disease, treatment and intervention are found. We will also evaluate this by comparing childhood cancer patients receiving an exercise intervention to childhood cancer patients who did not receive an exercise intervention.