Exercise interventions for children and young adults during and after treatment for childhood cancer

  • Protocol
  • Intervention

Authors

  • Katja I Braam,

    1. VU University Medical Center, Department of Pediatrics, Division of Oncology/Hematology, Amsterdam, Netherlands
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  • Patrick van der Torre,

    Corresponding author
    1. Wilhelmina Children's Hospital, University Medical Center Utrecht, Child Development and Exercise Center, Utrecht, Netherlands
    • Patrick van der Torre, Child Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, PO Box 85090, Utrecht, 3508 AB, Netherlands. p.vandertorre@umcutrecht.nl.

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    • Joint first authorship with Katja I. Braam

  • Tim Takken,

    1. Wilhelmina Children's Hospital, University Medical Center Utrecht, Child Development and Exercise Center, Utrecht, Netherlands
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  • Margreet A Veening,

    1. VU University Medical Center, Department of Pediatrics, Division of Oncology/Hematology, Amsterdam, Netherlands
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  • Eline van Dulmen-den Broeder,

    1. VU University Medical Center, Department of Pediatrics, Division of Oncology/Hematology, Amsterdam, Netherlands
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  • Gertjan JL Kaspers

    1. VU University Medical Center, Department of Pediatrics, Division of Oncology/Hematology, Amsterdam, Netherlands
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective

The aim of this review is to evaluate the effect of exercise on physical fitness (e.g. aerobic capacity, muscle strength or functional performance), of children who received an exercise intervention within the first five years of diagnosis of cancer (during and after treatment), compared to a control group of childhood cancer patients who did not receive an exercise intervention.

Secondary objectives

In addition, we will determine whether exercise within the first five years of diagnosis has a positive effect on fatigue, anxiety, depression, self-efficacy and health-related quality of life (HrQOL) and will assess how many and which kind of adverse effects of the disease, treatment and intervention are found. We will also evaluate this by comparing childhood cancer patients receiving an exercise intervention to childhood cancer patients who did not receive an exercise intervention.