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Compression stockings for the initial treatment of varicose veins in patients without venous ulceration

  1. Sarah Shingler1,*,
  2. Lindsay Robertson2,
  3. Sheila Boghossian3,
  4. Marlene Stewart4

Editorial Group: Cochrane Vascular Group

Published Online: 9 DEC 2013

Assessed as up-to-date: 20 AUG 2013

DOI: 10.1002/14651858.CD008819.pub3


How to Cite

Shingler S, Robertson L, Boghossian S, Stewart M. Compression stockings for the initial treatment of varicose veins in patients without venous ulceration. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD008819. DOI: 10.1002/14651858.CD008819.pub3.

Author Information

  1. 1

    Oxford Outcomes, Oxford, UK

  2. 2

    The Freeman Hospital, Department of Vascular Surgery, Newcastle upon Tyne, UK

  3. 3

    The University of Edinburgh, Public Health Sciences, The Medical School, Edinburgh, UK

  4. 4

    University of Edinburgh, Centre for Population Health Sciences, Edinburgh, UK

*Sarah Shingler, Oxford Outcomes, Seacourt Tower, West Way, Oxford, OX2 0JJ, UK. shinglersl@hotmail.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 9 DEC 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Anderson 1990 {published data only}
  • Anderson JH, Geraghty JG, Wilson YT, Murray GD, McArdle CS, Anderson JR. Paroven and graduated compression hosiery for superficial venous insufficiency. Phlebology 1990;5:271-6.
  • Geraghty JC, Anderson JH, Wilson Y, McArdle CS, Anderson JR. A prospective randomised study to determine the efficacy of O-(b-hydroxyethyl)-rutosides and graduated compression hosiery in controlling varicose vein symptoms. Phlébologie 1989;2(s.316):881-3.
Chant 1985 {published data only}
Chant 1989 {published data only}
  • Chant ADB, Davies LJ, Pike JM, Sparks MJ. Support stockings in practical management of varicose veins. Phlebology 1989;4:167-9.
Chauveau 2000 {published data only}
Coughlin 2001 {published data only}
  • Coughlin LB, Gandy R, Rosser S, de Cossart L. Pregnancy and compression tights for varicose veins: a randomised trial. Phlebology 2001; Vol. 16, issue 1:47.
Jones 1980 {published data only}
  • Jones NA, Webb PJ, Rees RI, Kakkar VV. A physiological study of elastic compression stockings in venous disorders of the leg. British Journal of Surgery 1980;67(8):569-72.
  • Kakkar VV. A physiological study of elastic compression stockings in venous disorders of the leg. Phlébologie 1982;35(1):101-6.
Jungbeck 1997 {published data only}
  • Jungbeck C, Thulin I, Darenheim C, Norgren L. Graduated compression treatment in patients with chronic venous insufficiency: A study comparing low and medium grade compression stockings. Phlebology 1997;12(4):142-5.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Abramowitz 1973 {published data only}
Acsady 1996 {published data only}
  • Acsady G, Laczko A, Takacs A, Nemes A. Clinical experiences with detralex treatment of oedemas after varicectomy. International Angiology 1996; Vol. 15 Suppl 1, issue 2:3.
Austrell 1995 {published data only}
  • Austrell C, Thulin I, Norgren L. The effects of long term graduated compression treatment on venous function during pregnancy. Phlébologie 1995;1(1.3):643-6.
Benigni 2003 {published data only}
  • Benigni JP, Sadoun S, Allaert FA, Vin F. Efficacy of Class 1 elastic compression stockings in the early stages of chronic venous disease. A comparative study. International Angiology 2003;22(4):383-92.
Biswas 2007 {published data only}
  • Biswas S, Clark A, Shields DA. Randomised clinical trial of the duration of compression therapy after varicose vein surgery. European Journal of Vascular and Endovascular Surgery 2007;33(5):631-7.
Bond 1997 {published data only}
  • Bond R, Crocker G, Wilkins DC, Walker AJ, Ashley S. A prospective randomised trial to study patient acceptance of different compression dressings used in the postoperative management of varicose veins. Phlebology 1997; Vol. 12, issue 4:161.
Bond 1999 {published data only}
  • Bond R, Whyman MR, Wilkins DC, Walker AJ, Ashley S. A randomised trial of different compression dressings following varicose vein surgery. Phlebology 1999;14(1):9-11.
Derman 1989 {published data only}
Gandhi 1984 {published data only}
Griffin 2007 {published data only}
  • Griffin M, Kakkos SK, Geroulakos G, Nicolaides AN. Comparison of three intermittent pneumatic compression systems in patients with varicose veins: a hemodynamic study. International Angiology 2007;26(2):158-64.
  • Griffin M, Kakkos SK, Nicolaides AN. Comparison of three intermittent pneumatic compression systems in patients with varicose veins: a haemodynamic study. Phlebology 2006; Vol. 21, issue 3:154-5.
Guest 2003 {published data only}
  • Guest M, Smith JJ, Tripuraneni G, Howard A, Madden P, Greenhalgh RM, et al. Randomized clinical trial of varicose vein surgery with compression versus compression alone for the treatment of venous ulceration. Phlebology 2003;18(3):130-6.
Hamel-Desnos 2008 {published data only}
  • Hamel-Desnos CM, Guias B, Quehe P, Mesgard A, Desnos P, Ferre B, et al. Foam sclerotherapy of saphenous veins with or without compression stockings. Biological consequences on circulating blood - a controlled randomised study. Phlebology 2008; Vol. 23, issue 5:245-6.
Hamel-Desnos 2010 {published data only}
  • Hamel-Desnos CM, Guias BJ, Desnos PR, Mesgard A. Foam sclerotherapy of the saphenous veins: randomised controlled trial with or without compression. European Journal of Vascular and Endovascular Surgery 2010;39(4):500-7.
Hirai 2002 {published data only}
Horvath 1983 {published data only}
Houtermans-Auckel 2009 {published data only}
  • Houtermans-Auckel JP, van Rossum E, Teijink JA, Dahlmans AA, Eussen EF, Nicolai SP, et al. To wear or not to wear compression stockings after varicose vein stripping: a randomised controlled trial. European Journal of Vascular and Endovascular Surgery 2009;38(3):387-91.
Ibegbuna 1997 {published data only}
Isiklar 2003 {published data only}
  • Isiklar MH. Hypercompression after microsclerotherapy for venules and telangiectasias. Abstracts of the UIP World Congress Chapter Meeting 2003.
Kakkos 2001 {published data only}
  • Kakkos SK, Szendro G, Griffin M, Sabetai MM, Nicolaides AN. Improved hemodynamic effectiveness and associated clinical correlations of a new intermittent pneumatic compression system in patients with chronic venous insufficiency. Journal of Vascular Surgery 2001;34(5):915-22.
Kline 1972 {published data only}
  • Kline AL, Fegan WG. The use of Coban bandages in compression sclerotherapy. Journal of the Irish Medical Association 1972;65(11):290-3.
Lascasas 2009 {published data only}
  • Porto CL, Milhomens AL, Pires CE, Xavier SS, Sicuro F, Bottino DA, et al. Changes on venous diameter and leg perimeter with different clinical treatments for moderate chronic venous disease: evaluation using Duplex scanning and perimeter measurements. International Angiology 2009;28(3):222-31.
Leon 1993 {published data only}
  • Leon M, Volteas N, Labropoulos N, Kalodiki E, Chan P, Belcaro G, et al. The effect of elastic stockings on the elasticity of varicose veins. International Angiology 1993;12(2):173-7.
Makin 1982 {published data only}
  • Makin GS. Efficacy of compression bandaging. Phlébologie 1982;35(1):117-23.
Mariani 2011 {published data only}
  • Mariani F, Marone EM, Gasbarro V, Bucalossi M, Spelta S, Amsler F, et al. Multicenter randomized trial comparing compression with elastic stocking versus bandage after surgery for varicose veins. Journal of Vascular Surgery 2011;53(1):115-22.
Mauss 1969 {published data only}
  • Mauss HJ. [Essaven treatment of varicose veins in pregnancy]. Medizinische Welt 1969;41:2270-3.
Melrose 1979 {published data only}
Mosti 2009 {published data only}
  • Mosti G, Mattaliano V, Arleo S, Partsch H. Thigh compression after great saphenous surgery is more effective with high pressure. International Angiology 2009;28:274-80.
  • Mosti G, Mattaliano V, Partsch H. Thigh compression with different compression devices after great saphenous vein surgery. Phlebology 2009; Vol. 24:228-9.
Mosti 2011 {published data only}
  • Mosti G, Partsch H. Compression stockings with a negative pressure gradient have a more pronounced effect on venous pumping function than graduated elastic compression stockings. European Journal of Vascular and Endovascular Surgery 2011;42(2):261-6.
Norgren 1988 {published data only}
  • Norgren L. Elastic compression stockings - an evaluation with foot volumetry, strain-gauge plethysmography and photoplethylsmography. Acta Chirurgica Scandinavica 1988;154(9):505-7.
O'Hare 2010 {published data only}
  • Gloucestershire Hospitals NHS Foundation. A trial to compare the outcome of localised varicosity compression for 24 hours and 5 days after foam fclerotherapy to truncal varices. http://ClinicalTrials.gov/show/NCT00991497 2009.
  • O'Hare JL, Stephens J, Parkin D, Earnshaw JJ. Randomized clinical trial of different bandage regimens after foam sclerotherapy for varicose veins. British Journal of Surgery 2010;97(5):650-6.
Perhoniemi 1983 {published data only}
  • Perhoniemi V, Asp K. (Compression stockings and elastic bandage in the postoperative treatment of varicose veins). Suomen Laakarilehti 1983;38(1-2):31-4.
Pierson 1983 {published data only}
Rabe 2010 {published data only}
  • Rabe E. DAPS-dalteparin in patients with superficial leg vein phlebitis in addition to compression treatment - A placebo-controlled phase III study. Phlebolymphology 2010;17(1):14.
Raju 2007 {published data only}
Raraty 1999 {published data only}
  • Raraty MGT, Greaney MG, Blair SD. There is no benefit from 6 weeks' postoperative compression after varicose vein surgery: A prospective randomised trial. Phlebology 1999;14(1):21-5.
Schul 2009 {published data only}
  • Schul M, Eaton T, Erdman B. Compression therapy versus sclerotherapy for isolated refluxing reticular veins and telangiectasia: results of a randomised trial comparing quality-of-life outcomes. Phlebology 2009; Vol. 24:89.
Szendro 1992 {published data only}
  • Szendro G, Veller M, Fisher C, Christopoulos D, Belcaro G, Clarke H, et al. The effect of elastic compression on the venous tone in patients with varicose veins. VASA 1992;21(2):198-202.
Thaler 2001 {published data only}
  • Thaler E, Huch R, Huch A, Zimmermann R. Compression stockings prophylaxis of emergent varicose veins in pregnancy: a prospective randomised controlled study. Swiss Medical Weekly 2001;131(45-6):659-62.
Weiss 1999 {published data only}
Zhang 2004 {published data only}
  • Zhang H, Lu JJ, Zhang JW, Zhang BG. [The evaluation for the therapeutic effect and the clinical practicability of encircling constriction of superficial femoral vein in the treatment of primary deep venous insufficiency]. [Chinese]. Chung-Hua Wai Ko Tsa Chih [Chinese Journal of Surgery] 2004;42(18):1121-4.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
NCT00766974 {published data only}
  • NCT00766974. Compression aided management of edema in patients with C3 venous disease. http://clinicaltrials.gov/ct2/show/NCT00766974?term=compression+and+varicose&rank=5 NCT00766974 2008.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Bamigboye 2007
Beale 2005
Campbell 2006
Clarke 2006
Edwards 2009
  • Edwards AG, Baynham S, Lees T, Mitchell DC. Management of varicose veins: a survey of current practice by members of the Vascular Society of Great Britain and Ireland. Annals of The Royal College of Surgeons of England 2009;91(1):77-80.
Eklöf 2004
  • Eklöf B, Rutherford RB, Bergan JJ, Carpentier PH, Gloviczki P, Kistner RL, et al. Revision of the CEAP classification for chronic venous disorders: consensus statement. Journal of Vascular Surgery 2004;40(6):1248-52.
Golledge 2003
Higgins 2009
  • Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions. Version 5.0.2. The Cochrane Collaboration, 2009. Available from www.cochrane-handbook.org. [Updated September 2009].
Johnson 2002
  • Johnson S. Compression hosiery in the prevention and treatment of venous leg ulcers. World Wide Wounds http://www.worldwidewounds.com/2002/september/Johnson/Compression-Hosiery-Leg-Ulcers.html September 2002.
Kolbach 2003
  • Kolbach DN, Sandbrink MWC, Prins MH, Neumann MAHM. Compression therapy for treating stage I and II (Widmer) post-thrombotic syndrome. Cochrane Database of Systematic Reviews 2003, Issue 4. [DOI: 10.1002/14651858.CD004177]
London 2000
Metcalfe 2008
  • Metcalfe M, Baker D. Varicose veins. Surgery (Oxford) 2008;26(1):4-7.
Padberg 2005
Palfreyman 2009
Partsch 2008
  • Partsch H, Flour M, Coleridge Smith P. Indications for compression therapy in venous and lymphatic disease Consensus based on experimental data and scientific evidence. Under the auspices of the IUP. International Angiology 2008;27(3):193-219.
Rabe 2008
  • Rabe E, Partsch H, Jünger M, Abel M, Achhammer I, Becker F, et al. Guidelines for clinical studies with compression devices in patients with venous disorders of the lower limb. European Journal of Vascular and Endovascular Surgery 2008;35(4):494-500.
Rajendran 2007
  • Rajendran S, Rigby AJ, Anand SC. Venous leg ulcer treatment and practice--part 3: The use of compression therapy systems. Journal of Wound care 2007;16(3):107-9.
Ramelet 2002
RevMan 2008 [Computer program]
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.0.25. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2008.
Rigby 2004
  • Rigby KA, Palfreyman SSJ, Beverley C, Michaels JA. Surgery versus sclerotherapy for the treatment of varicose veins. Cochrane Database of Systematic Reviews 2004, Issue 4. [DOI: 10.1002/14651858.CD004980]
Robertson 2008
Tisi 2006
Tisi 2007
  • Tisi P. Varicose veins. BMJ Clinical Evidence 2007;10.
Walker 2007
  • Walker L, Lamont S. Use and application of graduated elastic compression stockings. Nursing Standard 2007;21(42):41-5.

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Shingler 2011
  • Shingler S, Robertson L, Boghossian S, Stewart M. Compression stockings for the initial treatment of varicose veins in patients without venous ulceration. Cochrane Database of Systematic Reviews 2011, Issue 11. [DOI: 10.1002/14651858.CD008819.pub2]