Intervention Protocol

You have free access to this content

Vitamin D supplementation for preventing infections in children less than five years of age

  1. Mohammad Yawar Yakoob,
  2. Zulfiqar A Bhutta*

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 10 NOV 2010

DOI: 10.1002/14651858.CD008824

How to Cite

Yakoob MY, Bhutta ZA. Vitamin D supplementation for preventing infections in children less than five years of age (Protocol). Cochrane Database of Systematic Reviews 2010, Issue 11. Art. No.: CD008824. DOI: 10.1002/14651858.CD008824.

Author Information

  1. Aga Khan University Hospital, Division of Women and Child Health, Karachi, Pakistan

*Zulfiqar A Bhutta, Division of Women and Child Health, Aga Khan University Hospital, Stadium Road, PO Box 3500, Karachi, 74800, Pakistan. zulfiqar.bhutta@aku.edu.

Publication History

  1. Publication Status: New
  2. Published Online: 10 NOV 2010

SEARCH

References

Additional references

Akpede 1999
  • Akpede GO, Omotara BA, Ambe JP. Rickets and deprivation: a Nigerian study. Journal of the Royal Society for the Promotion of Health. 2000/02/16 1999; Vol. 119, issue 4:216-22.
Akpede 2001
  • Akpede GO, Solomon EA, Jalo I, Addy EO, Banwo AI, Omotara BA. Nutritional rickets in young Nigerian children in the Sahel savanna. East African Medical Journal. 2002/09/11 2001; Vol. 78, issue 11:568-75.
Aloia 2005
  • Aloia JF, Talwar SA, Pollack S, Yeh J. A randomized controlled trial of vitamin D3 supplementation in African American women. Archives of Internal Medicine. 2005/07/27 2005; Vol. 165, issue 14:1618-23.
Bhutta 2008
  • Bhutta ZA. Vitamin D and child health: some emerging issues. Maternal and Child Nutrition. 2008/03/14 2008; Vol. 4, issue 2:83-5.
Black 2008
  • Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, et al. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet. 2008/01/22 2008; Vol. 371, issue 9608:243-60.
Cannell 2008
  • Cannell JJ, Hollis BW. Use of vitamin D in clinical practice. Alternative Medicine Review. 2008/04/02 2008; Vol. 13, issue 1:6-20.
Cavalier 2009
  • Cavalier E, Delanaye P, Chapelle JP, Souberbielle JC. Vitamin D: current status and perspectives. Clinical Chemistry and Laboratory Medicine. 2008/12/23 2009; Vol. 47, issue 2:120-7.
Du 2001
  • Du X, Greenfield H, Fraser DR, Ge K, Trube A, Wang Y. Vitamin D deficiency and associated factors in adolescent girls in Beijing. The American Journal of Clinical Nutrition. 2001/09/22 2001; Vol. 74, issue 4:494-500.
Elidrissy 1984
  • Elidrissy AT, Sedrani SH, Lawson DE. Vitamin D deficiency in mothers of rachitic infants. Calcified Tissues International. 1984/05/01 1984; Vol. 36, issue 3:266-8.
Garabedian 1991
  • Garabedian M, Ben-Mekhbi H. Is vitamin D deficiency rickets a public health problem in France and Algeria?. Rickets in India. New York: Raven, 1991:247-52.
Ghai 1991
Grant 2009
  • Grant CC, Wall CR, Crengle S, Scragg R. Vitamin D deficiency in early childhood: prevalent in the sunny South Pacific. Public Health Nutrition. 2009/02/24 2009; Vol. 12, issue 10:1893-901.
Health Canada
  • Vitamin D supplementation: Recommendations for Canadian mothers and infants. Paediatrics and Child Health. 2008/11/26 2007; Vol. 12, issue 7:583-98.
Higgins 2008
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions: Version 5.0.1 [updated September 2008]. The Cochrane Collaboration 2008. Available from www.cochrane-handbook.org (accessed 31 July 2010).
Holick 2008
  • Holick MF. Vitamin D: a D-Lightful health perspective. Nutrition Reviews. 2008/12/05 2008; Vol. 66, issue 10 Suppl 2:S182-94.
Janssen 2007
  • Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, et al. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. Journal of Infectious Diseases. 2007/08/19 2007; Vol. 196, issue 6:826-34.
Karatekin 2009
  • Karatekin G, Kaya A, Salihoglu O, Balci H, Nuhoglu A. Association of subclinical vitamin D deficiency in newborns with acute lower respiratory infection and their mothers. European Journal of Clinical Nutrition 2009;63(4):473-7.
Lawson 1999
  • Lawson M, Thomas M. Vitamin D concentrations in Asian children aged 2 years living in England: population survey. BMJ. 1999/01/05 1999; Vol. 318, issue 7175:28.
Lehtonen-Veromaa 1999
  • Lehtonen-Veromaa M, Mottonen T, Irjala K, Karkkainen M, Lamberg-Allardt C, Hakola P, et al. Vitamin D intake is low and hypovitaminosis D common in healthy 9- to 15-year-old Finnish girls. European Journal of Clinical Nutrition. 1999/10/06 1999; Vol. 53, issue 9:746-51.
Leikina 2005
  • Leikina E, Delanoe-Ayari H, Melikov K, Cho MS, Chen A, Waring AJ, et al. Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins. Nature Immunololgy. 2005/09/13 2005; Vol. 6, issue 10:995-1001.
Manaseki-Holland 2008
  • Manaseki-Holland S, Zulf Mughal M, Bhutta Z, Qasem Shams M. Vitamin D status of socio-economically deprived children in Kabul, Afghanistan. International Journal for Vitamin and Nutrition Research. 2008/07/26 2008; Vol. 78, issue 1:16-20.
Manaseki-Holland 2010
  • Manaseki-Holland S, Qader G, Isaq Masher M, Bruce J, Zulf Mughal M, Chandramohan D, et al. Effects of vitamin D supplementation to children diagnosed with pneumonia in Kabul: a randomised controlled trial. Tropical Medicine and International Health 2010;15:1148-55.
Mansbach 2009
  • Mansbach JM, Ginde AA, Camargo CA, Jr. Serum 25-hydroxyvitamin D levels among US children aged 1 to 11 years: Do children need more vitamin D?. Pediatrics. 2009/12/03 2009; Vol. 124, issue 5:1404-10.
McNally 2009
Misra 2008
  • Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M. Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics. 2008/08/05 2008; Vol. 122, issue 2:398-417.
Muhe 1997
  • Muhe L, Lulseged S, Mason KE, Simoes EA. Case-control study of the role of nutritional rickets in the risk of developing pneumonia in Ethiopian children. Lancet. 1997/06/21 1997; Vol. 349, issue 9068:1801-4.
Najada 2004
  • Najada AS, Habashneh MS, Khader M. The frequency of nutritional rickets among hospitalized infants and its relation to respiratory diseases. Journal of Tropical Pediatrics 2004;50(6):364-8.
Nicolaidou 2006
  • Nicolaidou P, Hatzistamatiou Z, Papadopoulou A, Kaleyias J, Floropoulou E, Lagona E, et al. Low vitamin D status in mother-newborn pairs in Greece. Calcified Tissues International. 2006/07/11 2006; Vol. 78, issue 6:337-42.
Nnoaham 2008
  • Nnoaham KE, Clarke A. Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis. International Journal of Epidemiology. 2008/02/05 2008; Vol. 37, issue 1:113-9.
Ozgur 1996
  • Ozgur S, Sumer H, Kocoglu G. Rickets and soil strontium. Archives of Disease in Childhood. 1996/12/01 1996; Vol. 75, issue 6:524-6.
Prentice 2008
  • Prentice A. Vitamin D deficiency: a global perspective. Nutrition Reviews. 2008/12/05 2008; Vol. 66, issue 10 Suppl 2:S153-64.
Roth 2009
Salimpour 1975
  • Salimpour R. Rickets in Tehran. Study of 200 cases. Archives of Disease in Childhood. 1975/01/01 1975; Vol. 50, issue 1:63-6.
Sichert-Hellert 2006
  • Sichert-Hellert W, Wenz G, Kersting M. Vitamin intakes from supplements and fortified food in German children and adolescents: results from the DONALD study. Journal of Nutrition. 2006/04/15 2006; Vol. 136, issue 5:1329-33.
Wagner 2008
  • Wagner CL, Greer FR. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics. 2008/11/04 2008; Vol. 122, issue 5:1142-52.
Wagner 2008a
  • Wagner CL, Taylor SN, Hollis BW. Does vitamin D make the world go 'round'?. Breastfeeding Medicine. 2008/12/18 2008; Vol. 3, issue 4:239-50.
Walker 2009
  • Walker VP, Modlin RL. The vitamin D connection to pediatric infections and immune function. Pediatric Research 2009; Vol. 65, issue 5 Pt 2:R106-13.
Ward 2007
  • Ward LM, Gaboury I, Ladhani M, Zlotkin S. Vitamin D-deficiency rickets among children in Canada. Canadian Medical Association Journal. 2007/06/30 2007; Vol. 177, issue 2:161-6.
Wayse 2004
  • Wayse V, Yousafzai A, Mogale K, Filteau S. Association of subclinical vitamin D deficiency with severe acute lower respiratory infection in Indian children under 5 y. European Journal of Clinical Nutrition. 2004/03/26 2004; Vol. 58, issue 4:563-7.
White 2008
  • White JH. Vitamin D signaling, infectious diseases, and regulation of innate immunity. Infection and Immunity. 2008/05/29 2008; Vol. 76, issue 9:3837-43. [: (Electronic)]
Williams 2008
  • Williams B, Williams AJ, Anderson ST. Vitamin D deficiency and insufficiency in children with tuberculosis. The Pediatric Infectious Disease Journal. 2008/09/09 2008; Vol. 27, issue 10:941-2.
Yim 2007
  • Yim S, Dhawan P, Ragunath C, Christakos S, Diamond G. Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3). Journal of Cystic Fibrosis. 2007/05/01 2007; Vol. 6, issue 6:403-10.
Zhao 1991
  • Zhao XH. Rickets in China. Rickets. New York: Raven, 1991:253-61.
Zhao 1992
  • Zhao XH. Nutritional situation of Beijing residents. Southeast Asian Journal of Tropical Medicine and Public Health. 1992/01/01 1992; Vol. 23 Suppl 3:65-8.
Zipitis 2006
  • Zipitis CS, Markides GA, Swann IL. Vitamin D deficiency: prevention or treatment?. Archives of Disease in Childhood. 2006/09/02 2006; Vol. 91, issue 12:1011-4.