Safety of non-steroidal anti-inflammatory drugs and/or paracetamol in people receiving methotrexate for inflammatory arthritis

  • Protocol
  • Intervention

Authors

  • Alexandra N Colebatch,

    Corresponding author
    1. Southampton General Hospital, Department of Rheumatology, Southampton; Consultant Rheumatologist Yeovil District Hospital, Somerset, Hampshire, UK
    • Alexandra N Colebatch, Department of Rheumatology, Southampton General Hospital, Tremona Road, Southampton; Consultant Rheumatologist Yeovil District Hospital, Somerset, Hampshire, SO16 6YD, UK. a_colebatch@hotmail.com.

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  • Jonathan L Marks,

    1. Southampton General Hospital, Department of Rheumatology, Southampton, Hampshire, UK
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  • Christopher J Edwards

    1. Southampton General Hospital, Department of Rheumatology, Southampton, Hampshire, UK
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To systematically assess and collate the scientific evidence on the safety and adverse effects of using NSAIDs and/or paracetamol with MTX in inflammatory arthritis.

To identify gaps in the current evidence, to assess the implications of those gaps and to make recommendations for future research to address these deficiencies.