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Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age

  1. Luz Maria De-Regil1,*,
  2. Parminder S Suchdev2,
  3. Gunn E Vist3,
  4. Silke Walleser4,
  5. Juan Pablo Peña-Rosas5

Editorial Group: Cochrane Developmental, Psychosocial and Learning Problems Group

Published Online: 7 SEP 2011

Assessed as up-to-date: 10 AUG 2011

DOI: 10.1002/14651858.CD008959.pub2


How to Cite

De-Regil LM, Suchdev PS, Vist GE, Walleser S, Peña-Rosas JP. Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age. Cochrane Database of Systematic Reviews 2011, Issue 9. Art. No.: CD008959. DOI: 10.1002/14651858.CD008959.pub2.

Author Information

  1. 1

    Micronutrient Initiative, Ottawa, ON, Canada

  2. 2

    Emory University; Centers for Disease Control & Prevention (CDC), Pediatrics and Global Health; Nutrition Branch, Atlanta, GA, USA

  3. 3

    Norwegian Knowledge Centre for the Health Services, Prevention, Health Promotion and Organisation Unit, Oslo, Norway

  4. 4

    Independent Consultant, Geneva, Switzerland

  5. 5

    World Health Organization, Evidence and Programme Guidance, Department of Nutrition for Health and Development, Geneva, Switzerland

*Luz Maria De-Regil, Micronutrient Initiative, 180 Elgin Street, Suite 1000, Ottawa, ON, K2P 2K3, Canada. lderegil@micronutrient.org.

Publication History

  1. Publication Status: Edited (no change to conclusions), comment added to review
  2. Published Online: 7 SEP 2011

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[Figure 1]
Figure 1. Study flow diagram
[Figure 2]
Figure 2. Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Figure 3]
Figure 3. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 1 Anaemia (ALL).
[Analysis 1.2]
Analysis 1.2. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 2 Anaemia (SUBGROUPS).
[Analysis 1.3]
Analysis 1.3. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 3 Iron deficiency (ALL).
[Analysis 1.4]
Analysis 1.4. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 4 Iron deficiency (SUBGROUPS).
[Analysis 1.5]
Analysis 1.5. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 5 Haemoglobin (g/L) (ALL).
[Analysis 1.6]
Analysis 1.6. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 6 Haemoglobin (g/L) (SUBGROUPS).
[Analysis 1.7]
Analysis 1.7. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 7 Iron status (ferritin concentrations in μg/L) (ALL).
[Analysis 1.8]
Analysis 1.8. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 8 Weight-for-age (in Z-scores) (ALL).
[Analysis 1.9]
Analysis 1.9. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 9 Length-for-age (in Z-scores).
[Analysis 1.10]
Analysis 1.10. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 10 Weight-for-length (in Z-scores).
[Analysis 1.11]
Analysis 1.11. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 11 Any cause morbidity.
[Analysis 1.12]
Analysis 1.12. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 12 Malaria smears.
[Analysis 1.13]
Analysis 1.13. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 13 Diarrhoea (ALL).
[Analysis 1.14]
Analysis 1.14. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 14 Recurrent diarrhoea (not pre-specified).
[Analysis 1.15]
Analysis 1.15. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 15 Upper respiratory infections.
[Analysis 1.16]
Analysis 1.16. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 16 Serum zinc.
[Analysis 1.17]
Analysis 1.17. Comparison 1 Provision of multiple micronutrient powders versus no intervention or placebo, Outcome 17 Walking independently.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 1 Anaemia (ALL).
[Analysis 2.2]
Analysis 2.2. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 2 Haemoglobin (g/L) (ALL).
[Analysis 2.3]
Analysis 2.3. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 3 Diarrhoea (ALL).
[Analysis 2.4]
Analysis 2.4. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 4 Diarrhoea episodes (ALL) (not pre-specified).
[Analysis 2.5]
Analysis 2.5. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 5 Vomiting (ALL) (not pre-specified).
[Analysis 2.6]
Analysis 2.6. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 6 Staining of teeth (ALL) (not pre-specified).
[Analysis 2.7]
Analysis 2.7. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 7 Stool discolouration (ALL) (not pre-specified).
[Analysis 2.8]
Analysis 2.8. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 8 Cough (ALL) (not pre-specified).
[Analysis 2.9]
Analysis 2.9. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 9 Cold (ALL) (not pre-specified).
[Analysis 2.10]
Analysis 2.10. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 10 Fever (ALL) (not pre-specified).
[Analysis 2.11]
Analysis 2.11. Comparison 2 Provision of multiple micronutrient powders versus iron supplements, Outcome 11 Recurrent diarrhoea (3 or more episodes) (ALL) (not pre-specified).