Intervention Protocol

Sequential versus standard triple therapy for Helicobacter pylori eradication

  1. Olga P Nyssen1,
  2. Adrian G McNicholl1,
  3. Francis Megraud2,
  4. Vincenzo Savarino3,
  5. Giuseppina Oderda4,
  6. Carlo Fallone5,
  7. Lori Fischbach6,
  8. Franco Bazzoli7,
  9. Javier P Gisbert1,*

Editorial Group: Cochrane Upper Gastrointestinal and Pancreatic Diseases Group

Published Online: 16 MAR 2011

DOI: 10.1002/14651858.CD009034


How to Cite

Nyssen OP, McNicholl AG, Megraud F, Savarino V, Oderda G, Fallone C, Fischbach L, Bazzoli F, Gisbert JP. Sequential versus standard triple therapy for Helicobacter pylori eradication (Protocol). Cochrane Database of Systematic Reviews 2011, Issue 3. Art. No.: CD009034. DOI: 10.1002/14651858.CD009034.

Author Information

  1. 1

    Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Madrid, Spain

  2. 2

    Hôpital Pellegrin, Bactériologie-Enfants, Bordeaux, Cedex, France

  3. 3

    Universita di Genova, Dipartimento di Medicina Interna e Specialita Mediche, Genova, Italy

  4. 4

    Universita del Piemonte Orientale, Paediatric Endoscopy Units, Novara, Italy

  5. 5

    McGill University Health Centre, Faculty of Medicine, Montreal, Quebec, Canada

  6. 6

    University of North Texas Health Science Center, Department of Epidemiology, Fort Worth, Texas, USA

  7. 7

    Universit degli Studi di Bologna, Dipartimento di Medicina Interna e Gastroenterologia, Bologna, Italy

*Javier P Gisbert, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Madrid, 28006, Spain. gisbert@meditex.es.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 16 MAR 2011

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective

To conduct a meta-analysis of randomized controlled trials (RCTs) comparing the efficacy of a sequential regimen with standard triple therapy for the eradication of H. pylori infection.

Secondary objective

To compare the incidence of adverse effects associated with both standard triple and sequential H. pylori eradication therapies.