Oral antiviral therapy for prevention of genital herpes outbreaks in immunocompetent and nonpregnant patients

  • Protocol
  • Intervention



This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

We aim to assess the relative effectiveness and safety of competing oral antiviral drugs (ACV, FCV and VCV) prescribed to suppress recurrent genital herpes. In other words, we aim to assess the three possible pair-wise comparisons of each antiviral drug against each other.

In addition, we aim to assess whether the effectiveness depends on drug doses and regimen.