This is the protocol for a review and there is no abstract. The objectives are as follows:
To assess the effects of weaning by protocol for invasively ventilated critically ill children.
To compare the total duration of invasive mechanical ventilation of critically ill children who are weaned using protocols versus usual (non-protocolized) practice.
To ascertain any differences between protocolized weaning and usual care in terms of mortality, adverse events, ICU length of stay, and quality of life.