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Neuropsychological rehabilitation for multiple sclerosis

  1. Eija M Rosti-Otajärvi1,
  2. Päivi I Hämäläinen2,*

Editorial Group: Cochrane Multiple Sclerosis and Rare Diseases of the Central Nervous System Group

Published Online: 11 FEB 2014

Assessed as up-to-date: 28 MAY 2013

DOI: 10.1002/14651858.CD009131.pub3


How to Cite

Rosti-Otajärvi EM, Hämäläinen PI. Neuropsychological rehabilitation for multiple sclerosis. Cochrane Database of Systematic Reviews 2014, Issue 2. Art. No.: CD009131. DOI: 10.1002/14651858.CD009131.pub3.

Author Information

  1. 1

    Tampere University Hospital, Department of Neurology and Rehabilitation, Tampere, Finland

  2. 2

    Finnish MS Association, Masku neurological rehabilitation centre, Masku, Finland

*Päivi I Hämäläinen, Masku neurological rehabilitation centre, Finnish MS Association, Seppäläntie 90, Masku, 21250, Finland. paivi.hamalainen@ms-liitto.fi.

Publication History

  1. Publication Status: New search for studies and content updated (conclusions changed)
  2. Published Online: 11 FEB 2014

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Benedict 2000 {published and unpublished data}
  • Benedict RH, Shapiro A, Priore R, Miller C, Munschauer F, Jacobs L. Neuropsychological counseling improves social behavior in cognitively-impaired multiple sclerosis patients. Multiple Sclerosis 2000;6:391-6.
Brissart 2012 {published data only}
  • Brissart H, Leroy M, Morele E, Baumann C, Spitz E, Debouverie M. Cognitive rehabilitation in multiple sclerosis. Neurocase 2012 Aug 1 [Epub ahead of print].
Cerasa 2012 {published data only}
  • Cerasa A, Gioia MC, Valentino P, Nistico R, Chiriaco C, Pirritano D, et al. Computer-assisted cognitive rehabilitation of attention deficits for multiple sclerosis: a randomized trial with fMRI correlates. Neurorehabilitation and Neural Repair 2012;27(4):284-95.
Chiaravalloti 2005 {published and unpublished data}
  • Chiaravalloti ND, DeLuca J, Moore NB, Ricker JH. Treating learning impairments improves memory performance in multiple sclerosis: a randomised clinical trial. Multiple Sclerosis 2005;11:58-68.
Filippi 2012 {published data only}
  • Filippi M, Riccitelli G, Mattiloli F, Capra R, Stampatori C, Pagani E, et al. Multiple sclerosis: effects of cognitive rehabilitation on structural and functional MR imaging measures - an explorative study. Radiology 2012;262(3):932-40.
Fink 2010 {published data only}
  • Fink F, Rischkau E, Butt M, Klein J, Eling P, Hildebrandt H. Efficacy of an executive function intervention programme in MS: a placebo-controlled and pseudo-randomized study. Multiple Sclerosis 2010;16(9):1148-51.
Hildebrandt 2007 {published data only}
  • Hildebrandt H, Lanz M, Hahn HK, Hoffmann E, Schwarze B, Schwendemann G, et al. Cognitive training in MS: effects and relation to brain atrophy. Restorative Neurology and Neuroscience 2007;25:33-43.
Jonsson 1993 {published data only (unpublished sought but not used)}
  • Jonsson A, Korfitzen EM, Heltberg A, Ravnborg MH, Byskov-Ottosen E. Effects of neuropsychological treatment in patients with multiple sclerosis. Acta Neurologica Scandinavica 1993;88(6):394-400.
Lincoln 2002 {published and unpublished data}
  • Lincoln NB, Dent A, Harding J, Weyman N, Nicholl C, Blumhardt LD, et al. Evaluation of cognitive assessment and cognitive intervention for people with multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry 2002;72:93-8.
Mäntynen 2013 {published data only}
  • Mäntynen A, Rosti-Otajärvi E, Koivisto K, Lilja A, Huhtala H, Hämäläinen P. Neuropsychological rehabilitation does not improve cognitive performance but reduces perceived cognitive deficits in patients with multiple sclerosis: a randomized controlled multi-centre trial. Multiple Sclerosis Journal 2013 Jun 26 [Epub ahead of print].
Mattioli 2010 {published and unpublished data}
  • Mattioli F, Stampatori C, Zanotti D, Parrinello G, Capra R. Efficacy and specificity of intensive cognitive rehabilitation of attention and executive functions in multiple sclerosis. Journal of the Neurological Sciences 2010;288:101-5.
Mattioli 2012a {published data only}
  • Mattioli F, Stampatori C, Scarpazza C, Parrinello G, Capra R. Persistence of the effects of attention and executive functions intensive rehabilitation in relapsing remitting multiple sclerosis. Multiple Sclerosis and Related Disorders 2012;1:168-73.
Mendoza 2001 {published data only}
  • Mendoza RJ, Pittenger DJ, Weinstein CS. Unit management of depression of patients with multiple sclerosis using cognitive remediation strategies: a preliminary study. Neurorehabilitation and Neural Repair 2001;15(1):9-14.
Mendozzi 1998 {published data only}
  • Mendozzi L, Pugnetti L, Motta A, Barbieri E, Gambini A, Cazzullo CL. Computer-assisted memory retraining of patients with multiple sclerosis. Italian Journal of Neurological Sciences 1998;19:431-8.
Shatil 2010 {published and unpublished data}
  • Shatil E, Metzer A, Horvitz O, Miller A. Home-based personalized cognitive training in MS patients: a study of adherence and cognitive performance. NeuroRehabilitation 2010;26:143-53.
Solari 2004 {published data only}
  • Solari A, Motta A, Mendozzi L, Pucci E, Forni M, Mancardi G, et al. Computer-aided retraining of memory and attention in people with multiple sclerosis: a randomised, double-blind controlled trial. Journal of the Neurological Sciences 2004;222:99-104.
Stuifbergen 2012 {published data only}
  • Stuifbergen AK, Becker H, Perez F, Morison J, Kullberg V, Todd A. A randomized controlled trial of a cognitive rehabilitation intervention for persons with multiple sclerosis. Clinical Rehabilitation 2012;26(10):882-93.
Tesar 2005 {published and unpublished data}
  • Tesar N, Bandion K, Baumhackl U. Efficacy of a neuropsychological training programme for patients with multiple sclerosis - a randomised controlled trial. Wiener Klinische Wochenschrift 2005;117:747-54.
Vogt 2008 {published data only}
  • Vogt A, Kappos L, Stöcklin M, Gschwind L, Opwis K, Penner I-K. BrainStim - Wirksamkeit eines neu entwickelten kognitiven trainingsprogramms bei MS. Neurologie & Rehabilitation 2008;14(2):93-101.
Vogt 2009 {published data only}
  • Vogt A, Kappos L, Calabrese P, Stöcklin M, Gschwind L, Opwis K, et al. Working memory training in patients with multiple sclerosis - comparison of two different training schedules. Restorative Neurology and Neuroscience 2009;27:225-35.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Allen 1995 {published data only}
  • Allen DN, Longmore S, Goldstein G. Memory training and multiple sclerosis: a case study. International Journal of Rehabilitation and Health 1995;1(3):189-202.
Allen 1998 {published data only}
  • Allen DN, Goldstein G, Heyman RA, Rondinelli T. Teaching memory strategies to persons with multiple sclerosis. Journal of Rehabilitation Research and Development 1998;35(4):405-10.
Altinkaya 2012 {published data only}
  • Altinkaya A, Guclu I, Kurt E, Bingol A, Yandim Kuscu D, Sutlas PN, et al. Long-term effects of cognitive rehabilitation in multiple sclerosis: 12 months follow-up. European Journal of Neurology 2012;19:715.
Basso 2006 {published data only}
  • Basso MR, Lowery N, Ghormley C, Combs DM, Johnson J. Self-generated learning in people with multiple sclerosis. Journal of the International Neuropsychological Society 2006;12:640-8.
Basso 2007 {published data only}
  • Basso MR, Ghormley C, Lowery N, Combs D, Bornstein RA. Self-generated learning in people with multiple sclerosis: an extension of Chiaravalloti and DeLuca (2002). Journal of Clinical and Experimental Neuropsychology 2007;12:1-7.
Ben 2012 {published data only}
  • Ben AE, Hertzman G, Mosberg-Galili R, Hellmann M. Cognitive rehabilitation: functional strategies, problem-solving, and self-management skills for clients with multiple sclerosis. Multiple Sclerosis 2012;18:45-6.
Birnboim 2004 {published data only}
  • Birnboim S, Miller A. Cognitive rehabilitation for multiple sclerosis patients with executive dysfunction. Journal of Cognitive Rehabilitation 2004;22:11-8.
Bombardier 2008 {published data only}
  • Bombardier CH, Cunniffe M, Wadhwani R, Gibbons LE, Blake KD, Kraft GH. The efficacy of telephone counseling for health promotion in people with multiple sclerosis: A randomised controlled trial. Archives of Physical Medicine and Rehabilitation 2008;89:1849-56.
Brenk 2008 {published data only}
Brissart 2010 {published data only}
  • Brissart H, Leroy M, Debouverie M. Cognitive rehabilitation in multiple sclerosis: preliminary results and presentation of a new program, PROCOG-SEP [Premiere evaluation d'un programme de remediation cognitive chez des patients atteints de sclerose en plaques: PROCOG-SEP]. Revue Neurologique 2010;166:406-11.
Chiaravalloti 2002 {published data only}
Chiaravalloti 2003 {published data only}
Chiaravalloti 2011 {published data only}
  • Chiaravalloti ND. The modified story memory technique to treat learning and memory deficits in multiple sclerosis. Multiple Sclerosis 2011;17:43.
Chiaravalloti 2012 {published data only}
das Nair 2012b {published data only}
  • das Nair R, Lincoln NB. Evaluation of rehabilitation of memory in neurological disabilities (ReMiND): a randomized controlled trial. Clinical Rehabilitation 2012;26(10):894-903.
Foley 1994 {published data only}
  • Foley FW, Dince WM, Bedell JR, LaRocca NG, Kalb R, Caruso LS, et al. Psychoremediation of communication skills for cognitively impaired persons with multiple sclerosis. Journal of Neurologic Rehabilitation 1994;8:165-76.
Gordon 1997 {published data only}
  • Gordon PA, Lam CS, Winter R. Interaction strain and persons with multiple sclerosis: effectiveness of a social skills program. Journal of Applied Rehabilitation Counselling 1997;28:5-11.
Goverover 2008 {published data only}
  • Goverover Y, Chiaravalloti N, DeLuca J. Self-generation to improve learning and memory of functional activities in persons with multiple sclerosis: meal preparation and managing finances. Archives of Physical Medicine and Rehabilitation 2008;89(8):1514-21.
Goverover 2011 {published data only}
  • Goverover Y, Basso M, Wood H, Chiaravalloti N, DeLuca J. Examining the benefits of combining two learning strategies on recall of functional information in persons with multiple sclerosis. Multiple Sclerosis 2011;17(12):1488-97.
Hubacher 2011 {published data only}
  • Hubacher M, Kappos L, Opwis K, Stocklin M, Weier K, Sprenger T, et al. Benefits of cognitive training in MS patients treated with INFB-1b. Schweizer Archiv fur Neurologie und Psychiatrie 2011;162:6-7.
Leavitt 2012 {published data only}
  • Leavitt VM, Wylie GR, Girgis PA, DeLuca J, Chiaravalloti ND. Increased functional connectivity within memory networks following memory rehabilitation in multiple sclerosis. Brain Imaging and Behavior 2012 Jun 16 [Epub ahead of print].
Lincoln 2003 {published data only}
  • Lincoln NB, Dent A, Harding J. Treatment of cognitive problems for people with multiple sclerosis. International Journal of Therapy and Rehabilitation 2003;10(9):412-5.
Longley 2012 {published data only}
  • Longley WA, Tate RL, Brown RF. A protocol for measuring the direct psychological benefit of neuropsychological assessment with feedback in multiple sclerosis. Brain Impairment 2012;13(2):238-55.
Mattioli 2012b {published data only}
  • Mattioli F, Stampatori C, Bellomi F, Capra R, Provinciali L, Compagnucci L, et al. Specific versus aspecific intensive cognitive training in MS: preliminary results of the SMICT study. Multiple Sclerosis 2012;18:48.
Panicari 2012 {published data only}
  • Panicari L, Rocca M, Valsasina P, Carla Riccitelli G, Mattioli F, Capra R, et al. Cognitive rehabilitation modifies functional connectivity of the anterior cingulate cortex in multiple sclerosis. Neurology 2012;78:78.
Parisi 2012 {published data only}
  • Parisi L, Rocca MA, Valsasina P, Panicari L, Mattioli F, Filippi M. Cognitive rehabilitation correlates with the functional connectivity of the anterior congulate cortex in patients with multiple sclerosis. Brain Imaging and Behavior 2012 Apr 19 [Epub ahead of print].
Pierfederici 2007 {published data only}
  • Pierfederici L, Bacci L, Morici C Catena L, Viti B, Morgantini A. Efficacy of a verbal-auditory rehabilitative training for attentional deficits on attentional and mnestic ability in MS patients: a controlled-randomised clinical trial. Multiple Sclerosis 2007;13:230.
Plohmann 1994 {published data only}
  • Plohmann A, Kappos L, Brunnschweiler H. Evaluation of a computer-based attention retraining program for patients with multiple sclerosis. Schweizer Archiv für Neurologie und Psychiatrie 1994;145:35-6.
Plohmann 1998 {published data only}
  • Plohmann AM, Kappos L, Ammann W, Thordai A, Wittwer A, Huber S, et al. Computer assisted retraining of attentional impairments in patients with multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry 1998;64:455-62.
Rigby 2008 {published data only}
Rodgers 1996 {published data only}
  • Rodgers D, Khoo K, MacEachen M, Oven M, Beatty WW. Cognitive therapy for multiple sclerosis: a preliminary study. Alternative Therapies 1996;2:70-4.
Sastre-Garriga 2010 {published data only}
  • Sastre-Garriga J, Alonso J, Renom M, Arevalo MJ, Gonzalez I, Galan I, et al. A functional magnetic resonance proof of concept pilot trial of cognitive rehabilitation in multiple sclerosis. Multiple Sclerosis Journal 2010;17(4):457-67.
Schwartz 1999 {published data only}
  • Schwartz CE. Teaching coping skills enhances quality of life more than peer support: results of a randomised trial with multiple sclerosis patients. Health Psychology 1999;18:211-20.
Shevil 2009 {published data only}
Stuifbergen 2011 {published data only}
  • Stuifbergen A, Becker H, Morgan S, Morrison J, Perez F. Home-based computer-assisted cognitive training: feasibility and perceptions of people with multiple sclerosis. International Journal of MS Care 2011;13:189-98.
Tesar 2003 {published data only}
Topcular 2011 {published data only}
  • Topcular B, Bingol A, Yildiz S, Tutuncu M, Demirci O, Saip S, et al. Long-term effects of cognitive rehabilitation in multiple sclerosis: six months follow-up. Multiple Sclerosis 2011;17:173-4.
Wassem 2003 {published data only}
  • Wassem R, Dudley W. Symptom management and adjustment of patients with multiple sclerosis: a 4-year longitudinal intervention study. Clinical Nursing Research 2003;12:102-17.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Brochet 2013 {published data only}
  • Brochet B. Randomised controlled clinical trial of cognitive rehabilitation in multiple sclerosis and assessment by neuroimaging. ClinicalTrials.gov.
Shevil 2013 {published data only}
  • Shevil E. Development and evaluation of a cognitive rehabilitation program for persons with multiple sclerosis. ClinicalTrials.gov.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
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References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Rosti-Otajärvi 2011