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Intervention Review

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Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children

  1. Louise Rose1,*,
  2. Marcus J Schultz2,
  3. Chris R Cardwell3,
  4. Philippe Jouvet4,
  5. Danny F McAuley5,6,
  6. Bronagh Blackwood7

Editorial Group: Cochrane Anaesthesia Group

Published Online: 6 JUN 2013

Assessed as up-to-date: 29 AUG 2012

DOI: 10.1002/14651858.CD009235.pub2


How to Cite

Rose L, Schultz MJ, Cardwell CR, Jouvet P, McAuley DF, Blackwood B. Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD009235. DOI: 10.1002/14651858.CD009235.pub2.

Author Information

  1. 1

    University of Toronto, Lawrence S. Bloomberg Faculty of Nursing, Toronto, ON, Canada

  2. 2

    Academic Medical Center, University of Amsterdam, Laboratory of Experimental Intensive Care and Anesthesiology, Amsterdam, Netherlands

  3. 3

    Queen's University Belfast, Centre for Public Health, Belfast, Northern Ireland, UK

  4. 4

    Sainte-Justine Hospital, University of Montreal, Department of Pediatrics, Montreal, Quebec, Canada

  5. 5

    Queen's University of Belfast, Centre for Infection and Immunity, Belfast, Northern Ireland, UK

  6. 6

    Royal Victoria Hospital, Regional Intensive Care Unit, Belfast, UK

  7. 7

    Queen's University Belfast, School of Medicine, Dentistry & Biomedical Sciences, Belfast, Northern Ireland, UK

*Louise Rose, Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, 155 College St, Toronto, ON, M5T 1P8, Canada. louise.rose@utoronto.ca.

Publication History

  1. Publication Status: New
  2. Published Online: 6 JUN 2013

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This is not the most recent version of the article. View current version (10 JUN 2014)

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Davis 1989 {published data only}
  • Davis S, Potgieter PD, Linton DM. Mandatory minute volume weaning in patients with pulmonary pathology. Anaesthesia and Intensive Care 1989;17(2):170-4. [PUBMED: 2719237]
Dongelmans 2009 {published data only}
  • Dongelsmans DA, Veelo DP, Paulus F, de Mol, BAJM, Korevaar JC, et al. Weaning automation with adaptive support ventilation: a randomized controlled trial in cardiothoracic surgery patients. Anesthesia and Analgesia 2009;108(2):565-71. [PUBMED: 19151288]
Hendrix 2006 {published data only}
  • Hendrix H, Kaiser ME, Yusen RD, Merk J. A randomized trial of automated versus conventional protocol-driven weaning from mechanical ventilation following coronary artery bypass surgery. European Journal of Cardio-thoracic Surgery 2006;29(6):957-63. [PUBMED: 16520042]
Jouvet 2011 {published and unpublished data}
  • Jouvet PA, Payen V, Gauvin F, Guillame E, Lacroix J. Weaning children from mechanical ventilation with a computer driven protocol: a pilot RCT. Intensive Care Medicine 2013;16(3):R85. [PUBMED: 22591622]
Kirakli 2011 {published and unpublished data}
  • Kirakli C, Ozdemir I, Ucar ZZ, Cimen P, Kepil S, Ozkan SA. Adaptive support ventilation for faster weaning in COPD: a randomised controlled trial. European Respiratory Journal 2011;38(4):774-80. [PUBMED: 21406514]
Lellouche 2006 {published data only}
  • Lellouche F, Mancebo J, Jolliet P, Roeseler J, Schortgen F, Dojat M, et al. A multicenter randomized trial of computer-driven protocolized weaning from mechanical ventilation. American Journal of Respiratory and Critical Care Medicine 2006;174(8):894-900. [PUBMED: 16840741]
Petter 2003 {published data only}
  • Petter AH, Chiolero RL, Cassina T, Chassot P-G, Müller XM, Revelly J-P. Automatic "respirator/weaning" with adaptive support ventilation: the effect on duration of endotracheal intubation and patient management. Anesthesia and Analgesia 2003;97(6):1743-50. [PUBMED: 14633553]
Rose 2008 {published and unpublished data}
  • Rose L, Presneill JJ, Johnston L, Cade JF. A randomised, controlled trial of conventional versus automated weaning from mechanical ventilation using SmartCare™/PS. Intensive Care Medicine 2008;34(10):1788-95. [PUBMED: 18575843]
Roth 2001 {published data only}
  • Roth H, Luecke T, Lansche G, Bender HJ, Quintel M. Effects of patient-triggered automatic switching between mandatory and supported ventilation in the postoperative weaning period. Intensive Care Medicine 2001;27(1):47-51. [PUBMED: 11280672]
Schaedler 2012 {published and unpublished data}
  • Schädler D, Engel C, Elke G, Pulletz S, Haake N, Frerichs I, et al. Automatic control of pressure support for ventilator weaning in surgical intensive care patients. American Journal of Respiratory and Critical Care Medicine 2012;185:637-44. [PUBMED: 22268137]
Stahl 2009 {unpublished data only}
  • Stahl C, Dahmen G, Ziegler A, Muhl E. Protocolized automated versus non-protocolized physician-directed weaning from mechanical ventilation: a controlled clinical trial. Unpublished data received from the author.
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Sulzer 2001 {published data only}
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Taniguchi 2009 {published data only}
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Walkey 2011 {published and unpublished data}
  • Walkey A, Reardon C. Clinical trial of a computer-driven weaning system for patients requiring mechanical ventilation. www.ClinicalTrials.gov 2011.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
East 1999 {published data only}
  • East TD, Heerman LK, Bradshaw RL, Lugo A, Sailors M, Ershler L, et al. Efficacy of a computerized decision support for mechanical ventilation: results of a prospective multi-centre randomized controlled trial. Proceedings of the American Medical Informatics Association 1999:251-5. [PUBMED: 10566359]
Jiang 2006 {published data only}
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Ma 2010 {published data only}
  • Ma Y, Yang X, Cao X, Ma X. A comparison of computer-driven weaning and physician-directed weaning from mechanical ventilation: a randomized prospective study. Chinese Journal of Tuberculosis and Respiratory Disease 2010;33(3):174-8. [PUBMED: 20450634]
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References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Burns 2013 {published and unpublished data}

 

Domingo 2010 {published data only (unpublished sought but not used)}

 

Lellouche 2009b {published data only (unpublished sought but not used)}

 

Lellouche 2013 {published and unpublished data}

 

Ramet 2002 {published data only (unpublished sought but not used)}

 

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Agarwal/Srinivusan 2010 {unpublished data only}
  • Adaptive Support Ventilation in Acute Respiratory Distress Syndrome (ARDS). Ongoing study January 2010.
Alander/Kontiokari 2009 {unpublished data only}
  • Neurally Adjusted Ventilatory Assist (NAVA) in Pediatric Patients. Ongoing study September 2009.
Beale 2004 {unpublished data only}
  • Comparison of an automated weaning programme and a standard clinical weaning protocol for weaning critically ill patients: a randomized controlled trial. Ongoing study Dec 1 2004.
Bosma 2010 {published data only}
  • Comparison of Weaning on Pressure Support vs. Proportional Assist Ventilation: a Pilot Study. Ongoing study March 2009.
Fernandez 2010 {unpublished data only}
  • Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients. Ongoing study Sept 2010.
Kirakli 2012 {unpublished data only}
  • Closed Loop Ventilation Strategy in Intensive Care Unit (ICU) Patients. Ongoing study April 2012.
Liu/Qui 2010 {unpublished data only}
  • Effect of NAVA on Duration of Weaning in Difficult to Wean Patients. Ongoing study December 2010.

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  4. References to ongoing studies
  5. Additional references
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