This is not the most recent version of the article. View current version (6 JUL 2016)

Diagnostic Test Accuracy Review

You have free access to this content

Diagnostic accuracy of laparoscopy following computed tomography (CT) scanning for assessing the resectability with curative intent in pancreatic and periampullary cancer

  1. Victoria B Allen1,
  2. Kurinchi Selvan Gurusamy2,*,
  3. Yemisi Takwoingi3,
  4. Amun Kalia4,
  5. Brian R Davidson2

Editorial Group: Cochrane Upper GI and Pancreatic Diseases Group

Published Online: 25 NOV 2013

Assessed as up-to-date: 13 SEP 2012

DOI: 10.1002/14651858.CD009323.pub2


How to Cite

Allen VB, Gurusamy KS, Takwoingi Y, Kalia A, Davidson BR. Diagnostic accuracy of laparoscopy following computed tomography (CT) scanning for assessing the resectability with curative intent in pancreatic and periampullary cancer. Cochrane Database of Systematic Reviews 2013, Issue 11. Art. No.: CD009323. DOI: 10.1002/14651858.CD009323.pub2.

Author Information

  1. 1

    Oxford University Hospitals NHS Trust, Oxford University Clinical Academic Graduate School, Oxford, UK

  2. 2

    Royal Free Campus, UCL Medical School, Department of Surgery, London, UK

  3. 3

    University of Birmingham, Public Health, Epidemiology and Biostatistics, Birmingham, UK

  4. 4

    University College London, London, UK

*Kurinchi Selvan Gurusamy, Department of Surgery, Royal Free Campus, UCL Medical School, Royal Free Hospital, Rowland Hill Street, London, NW3 2PF, UK. k.gurusamy@ucl.ac.uk.

Publication History

  1. Publication Status: New
  2. Published Online: 25 NOV 2013

SEARCH

This is not the most recent version of the article. View current version (06 JUL 2016)

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Ahmed 2006 {published data only}
  • Ahmed SI, Bochkarev V, Oleynikov D, Sasson AR. Patients with pancreatic adenocarcinoma benefit from staging laparoscopy. Journal of Laparoendoscopic & Advanced Surgical Techniques 2006;16(5):458-63.
Arnold 1999 {published data only}
  • Arnold JC, Neubauer HJ, Zopf T, Schneider A, Benz C, Adamek HE, et al. Improved tumor staging by diagnostic laparoscopy. Zeitschrift Fur Gastroenterologie 1999;37(6):483-8.
Arnold 2001a {published data only}
  • Arnold JC, Schneider AR, Zopf T, Neubauer HJ, Jakobs R, Benz C, et al. Laparoscopic tumor staging in gastrointestinal carcinomas: significance of internal medicine laparoscopy [Laparoskopisches tumorstaging bei gastrointestinalen karzinomen: bedeutung der internistischen laparoskopie]. Zeitschrift Fur Gastroenterologie 2001;39 Suppl 1:19-23.
Brooks 2002 {published data only}
  • Brooks AD, Mallis MJ, Brennan MF, Conlon KC. The value of laparoscopy in the management of ampullary, duodenal, and distal bile duct tumors. Journal of Gastrointestinal Surgery 2002; Vol. 6, issue 2:139-45.
Contreras 2009 {published data only}
Fernandez-Castillo 1995 {published data only}
  • Fernandez-Castillo C, Rattner DW, Warshaw AL. Further experience with laparoscopy and peritoneal cytology in the staging of pancreatic cancer. British Journal of Surgery 1995;82(8):1127-9.
John 1995 {published data only}
  • John TG, Greig JD, Carter DC, Garden OJ. Carcinoma of the pancreatic head and periampullary region. Tumor staging with laparoscopy and laparoscopic ultrasonography. Annals of Surgery 1995; Vol. 221, issue 2:156-64.
Kishiwada 2002 {published data only}
  • Kishiwada M, Kawarada Y, Taoka H, Isaji S. Management of advanced pancreatic cancer: Staging laparoscopy and immunochemotherapy - A new treatment strategy. Hepatogastroenterology 2002;49(48):1704-6.
Lavy 2012 {published data only}
  • Lavy R, Gatot I, Markon I, Shapira Z, Chikman B, Copel L, et al. The role of diagnostic laparoscopy in detecting minimal peritoneal metastatic deposits in patients with pancreatic cancer scheduled for curative resection. Surgical Laparoscopy, Endoscopy and Percutaneous Techniques 2012;22(4):358-60.
Menack 2001 {published data only}
  • Menack MJ, Spitz JD, Arregui ME. Staging of pancreatic and ampullary cancers for resectability using laparoscopy with laparoscopic ultrasound. Surgical Endoscopy 2001;15(10):1129-34.
Merchant 1998 {published data only}
Reddy 1999 {published data only}
  • Reddy KR, Levi J, Livingstone A, Jeffers L, Molina E, Kligerman S, et al. Experience with staging laparoscopy in pancreatic malignancy. Gastrointestinal Endoscopy 1999;49(4 Part 1):498-503.
Reed 1997 {published data only}
Shah 2008 {published data only}
  • Shah D, Fisher WE, Hodges SE, Wu MF, Hilsenbeck SG, Charles Brunicardi F. Preoperative prediction of complete resection in pancreatic cancer. The Journal of Surgical Research 2008;147(2):216-20.
Warshaw 1986 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Abdalla 2003 {published data only}
  • Abdalla EK, Barnett CC, Pisters PW, Cleary KR, Evans DB, Feig BW, et al. Subaquatic laparoscopy for staging of intraabdominal malignancy. Journal of the American College of Surgeons 2003;196(1):155-8.
Altieri 1982 {published data only}
  • Altieri A, Roggia G, Ciavarella G, Tricarico F. The contribution of laparoscopy to the diagnosis of abdominal masses. Personal experience. [Italian]. Minerva Chirurgica 1982;37(5):427-9.
Andren-Sandberg 1998 {published data only}
  • Andren-Sandberg A, Lindberg CG, Lundstedt C, Ihse I. Computed tomography and laparoscopy in the assessment of the patient with pancreatic cancer. Journal of the American College of Surgeons 1998;186(1):35-40.
Arnold 2001 {published data only}
  • Arnold JC, Schneider ARJ, Zopf T, Riemann JF. Laparoscopic tumor staging - A safe method in the hands of internists. Klinikarzt 2001;30(5):142-6.
Atanov 1972 {published data only}
  • Atanov YP, Gallinger YI. Laparoscopy in the diagnosis of some abdominal tumors. Sovetskaya Meditsina 1972;35(5):93-8.
Awad 1997 {published data only}
  • Awad SS, Colletti L, Mulholland M, Knol J, Rothman ED, Scheiman J, et al. Multimodality staging optimizes resectability in patients with pancreatic and ampullary cancer. American Surgeon 1997;63(7):634-8.
Balcom 2000 {published data only}
  • Balcom JH, Fernandez-del Castillo C. Can we predict resectability in pancreatic cancer?. Annals of Gastroenterology 2000;13(3):201-6.
Barabino 2011 {published data only}
  • Barabino M, Santambrogio R, Pisani Ceretti A, Scalzone R, Montorsi M, Opocher E. Is there still a role for laparoscopy combined with laparoscopic ultrasonography in the staging of pancreatic cancer?. Surgical Endoscopy 2011;25(1):160-5.
Barrat 1998 {published data only}
  • Barrat C, Champault G, Catheline JM. Is laparoscopic evaluation of digestive cancers legitimate? A prospective study of 109 cases. Annales De Chirurgie 1998;52(7):602-6.
Barreiro 2002 {published data only}
  • Barreiro CJ, Lillemoe KD, Koniaris LG, Sohn TA, Yeo CJ, Coleman J, et al. Diagnostic laparoscopy for periampullary and pancreatic cancer: what is the true benefit?. Journal of Gastrointestinal Surgery 2002;6(1):75-81.
Barthet 2007 {published data only}
Baumgarten 1984 {published data only}
  • Baumgarten R, Fengler JD. Current diagnostic value of laparoscopy. Zeitschrift für ärztliche Fortbildung 1984;78(20):841-2.
Beger 1997 {published data only}
  • Beger HG, Schoenberg MH. The role of laparoscopy and ultrasonography in pancreatic head carcinoma. HPB surgery 1997;10(3):186-8.
Belagyi 2000 {published data only}
  • Belagyi T, Olah A. Pancreatic head mass: what can be done? Diagnosis: laparoscopy. Journal of the Pancreas 2000;1(3 Suppl):123-6.
Bemelman 1995 {published data only}
Bohmig 2001 {published data only}
Borbath 2005 {published data only}
  • Borbath I, Van Beers BE, Lonneux M, Schoonbroodt D, Geubel A, Gigot JF, et al. Preoperative assessment of pancreatic tumors using magnetic resonance imaging, endoscopic ultrasonography, positron emission tomography and laparoscopy. Pancreatology 2005;5(6):553-61.
Boselli 2000 {published data only}
  • Boselli C, Trebuchet G, Bufalari A, De Santis F, Cirocchi R, Giustozzi G. Laparoscopic staging in surgical oncology. E.A.E.S: Proceedings of the 8th International Congress of the European Association for Endoscopic Surgery. 2000:647-52.
Bottger 1998 {published data only}
Boyce 1992 {published data only}
Caldironi 1996 {published data only}
  • Caldironi MW, Zani S, Mazzucco M, Paccagnella D, Aldinio MT, Costantin G, et al. Ultrasound-guided fine needle biopsy and laparoscopy in the study of pancreatic masses: report on 136 cases. General & Diagnostic Pathology 1996;141(5-6):313-8.
Callery 1997 {published data only}
  • Callery MP, Strasberg SM, Doherty GM, Soper NJ, Norton JA. Staging laparoscopy with laparoscopic ultrasonography: optimizing resectability in hepatobiliary and pancreatic malignancy. Journal of the American College of Surgeons 1997;185(1):33-9.
Callery 2009 {published data only}
  • Callery MP, Chang KJ, Fishman EK, Talamonti MS, William Traverso L, Linehan DC. Pretreatment assessment of resectable and borderline resectable pancreatic cancer: Expert consensus statement. Annals of Surgical Oncology 2009;16(7):1727-33.
Camacho 2005 {published data only}
  • Camacho D, Reichenbach D, Duerr GD, Venema TL, Sweeney JF, Fisher WE. Value of laparoscopy in the staging of pancreatic cancer. Journal of the Pancreas 2005;6(6):552-61.
Carmichael 1995 {published data only}
Carpenter 1996 {published data only}
Catheline 1998 {published data only}
  • Catheline JM, Polliand C, Risk N, Barrat C, Champault G. Staging of pancreatic cancer by laparoscopy and laparoscopic ultrasonography. Chirurgie 1998;123(3):271-9.
Catheline 1999 {published data only}
  • Catheline JM, Turner R, Rizk N, Barrat C, Champault G. The use of diagnostic laparoscopy supported by laparoscopic ultrasonography in the assessment of pancreatic cancer. Surgical Endoscopy 1999;13(3):239-45.
Chambon 1995 {published data only}
  • Chambon JP, Bosse JL, Denimal F, Porte H, Quandalle P. Place of celioscopy in the diagnosis of invasiveness of digestive cancers. Annales de Chirurgie 1995;49(6):513-8.
Champault 1996 {published data only}
  • Champault G, Catheline JM, Rizk N, Boutelier P. The use of laparoscopic ultrasound in the staging of pancreatic cancers. Annales De Chirurgie 1996;50(10):875-85.
Champault 1997 {published data only}
  • Champault G. The use of laparoscopic ultrasound in the assessment of pancreatic cancer. Wiad Lek 1997;50 Suppl Pt 1:195-203.
Charukhchyan 1998 {published data only}
  • Charukhchyan SA, Lucas GW. Lesser sac endoscopy and laparoscopy in pancreatic carcinoma definitive diagnosis, staging and palliation. American Journal of Surgery 1998;64(9):809-14.
Cipollone 2012 {published data only}
  • Cipollone I, Kelly M, Corbally C, Torreggiani W, Ridgway PF, Conlon KC. Is there still a utility for selected laparoscopic staging in pancreas cancer with contemporary multi detector CT scanning?. Pancreatology 2012;12(3):e12.
Conlon 1997 {published data only}
  • Conlon KCP, Minnard EA. The value of laparoscopic staging in upper gastrointestinal malignancy. Oncologist 1997;2(1):10-7.
Conlon 1999 {published data only}
Conlon 2002 {published data only}
Connor 2004 {published data only}
Croome 2009 {published data only}
  • Croome K, Jayaraman S, Schlachta C. Preoperative staging in cancer of the pancreatic head: is there room for improvement?. Asia-Pacific Journal of Clinical Oncology 2009;5:A192.
Croome 2010 {published data only}
  • Croome KP, Jayaraman S, Schlachta CM. Preoperative staging of cancer of the pancreatic head: Is there room for improvement?. Canadian Journal of Surgery 2010;53(3):171-4.
Cuesta 1993 {published data only}
Cuschieri 1978 {published data only}
Cuschieri 1988 {published data only}
D'Angelica 2003 {published data only}
  • D'Angelica M, Fong Y, Weber S, Gonen M, DeMatteo RP, Conlon K, et al. The role of staging laparoscopy in hepatobiliary malignancy: Prospective analysis of 401 cases. Annals of Surgical Oncology 2003;10(2):183-9.
Dadan 1980 {published data only}
  • Dadan H, Boron P, Szpakowicz T, Nowak H, Kurasz S, Zalewski J, et al. Diagnostic value of preoperative laparoscopy in detection of neoplastic changes. Polski Przeglad Chirurgiczny 1980;52(4):307-10.
Doran 2004 {published data only}
  • Doran HE, Bosonnet L, Connor S, Jones L, Garvey C, Hughes M, et al. Laparoscopy and laparoscopic ultrasound in the evaluation of pancreatic and periampullary tumours. Digestive Surgery 2004;21(4):305-13.
Doucas 2007 {published data only}
  • Doucas H, Sutton CD, Zimmerman A, Dennison AR, Berry DP. Assessment of pancreatic malignancy with laparoscopy and intraoperative ultrasound. Surgical Endoscopy 2007;21(7):1147-52.
Duffy 2008 {published data only}
Durup Scheel-Hincke 1999 {published data only}
  • Durup Scheel-Hincke J, Mortensen MB, Qvist N, Hovendal CP. TNM staging and assessment of resectability of pancreatic cancer by laparoscopic ultrasonography. Surgical Endoscopy 1999;13(10):967-71.
Eigler 1999 {published data only}
  • Eigler FW, Hossfeld DK, Junginger T, Kloppel G, Kruck P, Meyer HJ, et al. Guidelines for exocrine pancreas carcinoma. Onkologe 1999;5(3):257-60.
Ellsmere 2005 {published data only}
  • Ellsmere J, Mortele K, Sahani D, Maher M, Cantisani V, Wells W, et al. Does multidetector-row CT eliminate the role of diagnostic laparoscopy in assessing the resectability of pancreatic head adenocarcinoma?. Surgical Endoscopy 2005;19(3):369-73.
Enestvedt 2008 {published data only}
  • Enestvedt CK, Mayo SC, Diggs BS, Mori M, Austin DA, Shipley DK, et al. Diagnostic laparoscopy for patients with potentially resectable pancreatic adenocarcinoma: Is it cost-effective in the current era?. Journal of Gastrointestinal Surgery 2008;12(7):1177-84.
  • Mayo SC, Austin DF, Sheppard BC, Mori M, Shipley DK, Billingsley KG. Evolving preoperative evaluation of patients with pancreatic cancer: Does laparoscopy have a role in the current era?. Journal of the American College of Surgeons 2009;208(1):87-95.
Fernandez-Del 1994 {published data only}
  • Fernandez-Del Castillo C, Warshaw AL. Preoperative evaluation of adenocarcinoma of the pancreas: Massachusetts General Hospital experience. Cancer Bulletin 1994;46(6):492-8.
Fernandez-del 1998 {published data only}
  • Fernandez-del Castillo C, Warshaw AL. Laparoscopic staging and peritoneal cytology. Surgical Oncology Clinics of North America 1998;7(1):135-42.
Ferrone 2006 {published data only}
  • Ferrone CR, Haas B, Tang L, Coit DG, Fong Y, Brennan MF, et al. The influence of positive peritoneal cytology on survival in patients with pancreatic adenocarcinoma. Journal of Gastrointestinal Surgery 2006;10(10):1347-53.
Feussner 2000 {published data only}
  • Feussner H, Baumgartner M, Siewert JR. Extended diagnostic laparoscopy (EDL). Acta Chirurgica Austriaca 2000;32(5):212-20.
Fevery 1985 {published data only}
  • Fevery J, Baert AL, Marchal GM, Broeckaert L, De Groote J, Vantrappen G. The value of computed tomography, ultrasonography, and peritoneoscopy with biopsy in the detection of liver metastases secondary to gastro-enterological tumors. Acta Gastro-Enterologica Belgica 1985;48(2):105-10.
Fockens 1993 {published data only}
Friess 1997 {published data only}
  • Friess H, Baer HU, Sadowski C, Buchler MW. Efficacy and economic aspects of preoperative diagnosis: laparoscopy is useful in only 13% of patients with pancreatic carcinoma. Langenbecks Archiv für Chirurgie. Supplement. Kongressband 1997;114:474-6.
Friess 1998 {published data only}
  • Friess H, Kleeff J, Silva JC, Sadowski C, Baer HU, Buchler MW. The role of diagnostic laparoscopy in pancreatic and periampullary malignancies. Journal of the American College of Surgeons 1998;186(6):675-82.
Fristrup 2006 {published data only}
  • Fristrup CW, Mortensen MB, Pless T, Durup J, Ainsworth A, Hovendal C, et al. Combined endoscopic and laparoscopic ultrasound as preoperative assessment of patients with pancreatic cancer. HPB 2006;8(1):57-60.
Fukumoto 1989 {published data only}
  • Fukumoto Y, Okita K, Takemoto T. Utility of laparoscopic ultrasonography in the diagnosis of hepato-biliary and pancreatic carcinoma. Zeitschrift Fur Gastroenterologie 1989;27(Special Issue):92-7.
Garcea 2012 {published data only}
  • Garcea G, Cairns V, Berry DP, Neal CP, Metcalfe MS, Dennison AR. Improving the diagnostic yield from staging laparoscopy for periampullary malignancies: the value of preoperative inflammatory markers and radiological tumor size. Pancreas 2012;41(2):233-7.
Garofalo 2009 {published data only}
Gouma 1996 {published data only}
  • Gouma DJ, de Wit LT, Nieveen van Dijkum E, Van Delden O, Bemelman WA, Rauws EA, et al. Laparoscopic ultrasonography for staging of gastrointestinal malignancy. Scandinavian Journal of Gastroenterology 1996;31 Suppl 218:43-9.
Gouma 1999 {published data only}
Gouma 2002 {published data only}
Hann 1997 {published data only}
  • Hann LE, Conlon KC, Dougherty EC, Hilton S, Bach AM, Brennan MF. Laparoscopic sonography of peripancreatic tumors: Preliminary experience. American Journal of Roentgenology 1997;169(5):1257-62.
Healthcare 1999 {published data only}
  • Healthcare IBvoorz. Laparoscopy in pancreas cancer - primary research (brief record). Diemen: Healthcare Insurance Board/College voor Zorgverzekeringen (CVZ). 1999.
Heger 2008 {published data only}
  • Heger U, Buchler MW, Weitz J. Diagnostics of pancreatic carcinoma. Tumor Diagnostik und Therapie 2008;29(5):246-9.
Hernandezguio 1965 {published data only}
  • Hernandezguio C. Our experiences with laparoscopic exploration. Revista Española de las Enfermedades del Aparato Digestivo y de la Nutrición 1965;24:216-23.
Herrera 2003 {published data only}
  • Herrera MF, Velazquez D, Bezauri P, Angeles-Angeles A, Uscanga LF, Robles-Diaz G. Role of laparoscopy with ultrasound in the staging process of pancreatic and ampullary tumors. Gaceta Médica de México 2003;139(1):21-5.
Hidalgo 2004 {published data only}
  • Hidalgo Pascual M, Ferrero Herrero E, Castillo Fe MJ, Guadarrama Gonzalez FJ, Pelaez Torres P, Botella Ballesteros F. Epidemiology and diagnosis of the pancreatic cancer. Revista Espanola de Enfermedades Digestivas 2004;96(10):714-22.
Hohenberger 2000 {published data only}
  • Hohenberger P, Hunerbein M, Rau B, Schlag PM. Staging laparoscopy - indication, surgical technique and significance in the therapeutical concept of malignant tumors. Viszeralchirurgie 2000;35(1):2-7.
Holzman 1997 {published data only}
  • Holzman MD, Reintgen KL, Tyler DS, Pappas TN. The role of laparoscopy in the management of suspected pancreatic and periampullary malignancies. Journal of Gastrointestinal Surgery 1997;1(3):236-43.
Hunerbein 1999 {published data only}
  • Hunerbein M, Rau B, Schlag PM. Role of staging laparoscopy. Minimally invasive and endoscopic therapy in pancreas carcinoma. Onkologe 1999;5(3):203-7.
Hunerbein 2001 {published data only}
  • Hunerbein M, Rau B, Hohenberger P, Schlag PM. Value of laparoscopic ultrasound for staging of gastrointestinal tumors. Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2001;72(8):914-9.
Ialongo 2010 {published data only}
  • Ialongo P, Ferrarese F, Pannarale O, Panebianco A, Volpi A, Palasciano N. The role of laparoscopy in surgical treatment of pancreatic cancer [Il ruolo della laparoscopia nel trattamento chirurgico del carcinoma pancreatico]. Annali Italiani di Chirurgia 2010;81(4):295-9.
Ido 1982 {published data only}
  • Ido K. Laparoscopic observation of pancreatic cancer. Gastroenterological Endoscopy 1982;24(7):1164-5.
Ihse 1984 {published data only}
Ishida 1983 {published data only}
Ishida 1984 {published data only}
Ivanov 1989 {published data only}
  • Ivanov S, Keranov S. Laparoscopic assessment of the operability of pancreatic cancer. Khirurgiia 1989;42(1):12-4.
Jackowski 1997 {published data only}
  • Jackowski M, Juzkow H, Szeliga J, Zalucki M, Nowak M, Jedrzejczyk W. Laparoscopic staging in neoplastic diseases - Clinical experience. Acta Endoscopica Polona 1997;7(1):3-5.
Jakobs 1999 {published data only}
  • Jakobs R, Martin WR, Riemann JF. Current diagnostic possibilities of pancreas carcinoma. Onkologe 1999;5(3):194-202.
Jarnagin 2000 {published data only}
  • Jarnagin WR, Bodniewicz J, Dougherty E, Conlon K, Blumgart LH, Fong Y. A prospective analysis of staging laparoscopy in patients with primary and secondary hepatobiliary malignancies. Journal of Gastrointestinal Surgery 2000;4(1):34-42.
Jerby 1998 {published data only}
Jimenez 2000 {published data only}
  • Jimenez RE, Warshaw AL, Fernandez-Del Castillo C. Laparoscopy and peritoneal cytology in the staging of pancreatic cancer. Journal of Hepato-Biliary-Pancreatic Surgery 2000;7(1):15-20.
Jimenez 2000a {published data only}
  • Jimenez RE, Warshaw AL, Rattner DW, Willett CG, McGrath D, Fernandez-del Castillo C. Impact of laparoscopic staging in the treatment of pancreatic cancer. Archives of Surgery 2000;135(4):409-14.
John 1999 {published data only}
  • John TG, Wright A, Allan PL, Redhead DN, Paterson-Brown S, Carter DC, et al. Laparoscopy with laparoscopic ultrasonography in the TNM staging of pancreatic carcinoma. World Journal of Surgery 1999;23(9):870-81.
Juzkow 1996 {published data only}
  • Juzkow H, Jackowski M, Jedrzejczyk W. Laparoscopy as a diagnostic and therapeutic method in the treatment of pancreatic carcinoma. Acta Endoscopica Polona 1996;6(1):31-3.
Kadar 1997 {published data only}
  • Kadar E, Nagy P, Faludi S, Jakab F. Diagnostic-staging laparoscopy. Acta Chirurgica Hungarica 1997;36(1-4):160-1.
Kanazawa 1983 {published data only}
  • Kanazawa H, Sakamoto F, Makino T. Laparoscopy in upper GI malignancies. Gastroenterological Endoscopy 1983;25(9):1353-65.
Kaplan 1979 {published data only}
Karachristos 2005 {published data only}
Kellokumpu 1996 {published data only}
  • Kellokumpu I, Victorzon M. The role of laparoscopic staging in the assessment of metastasis of upper quadrant abdominal neoplasms. Duodecim 1996; Vol. 112, issue 4:257-62.
Kelly 2009 {published data only}
  • Kelly KJ, Wong J, Gladdy R, Moore-Dalal K, Woo Y, Gonen M, et al. Prognostic impact of RT-PCR-based detection of peritoneal micrometastases in patients with pancreatic cancer undergoing curative resection. Annals of Surgical Oncology 2009;16(12):3333-9.
Khamdanov 1983 {published data only}
Kiyonaga 1982 {published data only}
  • Kiyonaga G, Miyamoto S, Kita R, Yukawa E. Laparoscopy and biopsy. Nippon Rinsho 1982;40(3):660-9.
Klingler 2000 {published data only}
  • Klingler A, Klocker J, Springer R, Kober F, Glaser K. Combined laparoscopy and laparoscopic ultrasonography in the oncologic diagnostics of pancreas and liver. Acta Chirurgica Austriaca 2000;32(5):228-32.
Krahenbuhl 1997 {published data only}
Krustev 1998 {published data only}
  • Krustev N, Grigorov N. Laparoscopy and laparoscopic echography in the diagnosis of pancreatic diseases. Khirurgiia 1998;51(2):20-4.
Kubyshkin 2000 {published data only}
  • Kubyshkin VA, Vishnevskii VA, Airapetian AT, Karmazanovskii GG, Kuntsevich GI, Starkov IG. Differential diagnosis of pancreatic head cancer. Khirurgiia 2000;11:19-23.
Kuster 1967 {published data only}
Kwon 2002 {published data only}
Lavonius 2001 {published data only}
  • Lavonius MI, Laine S, Salo S, Sonninen P, Ovaska J. Role of laparoscopy and laparoscopic ultrasound in staging of pancreatic tumours. Annales Chirurgiae et Gynaecologiae 2001;90(4):252-5.
Lightdale 1992 {published data only}
Liu 2004 {published data only}
Long 2005 {published data only}
  • Long EE, Van Dam J, Weinstein S, Jeffrey B, Desser T, Norton JA. Computed tomography, endoscopic, laparoscopic, and intra-operative sonography for assessing resectability of pancreatic cancer. Surgical Oncology 2005;14(2):105-13.
Luque-de 1998 {published data only}
  • Luque-de Leon E, Tsiotos GG, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Staging laparoscopy for pancreatic cancer should be used to select the best palliation, not to increase resection rate. Gastroenterology 1998;114(4):A1407.
Luque-de 1999 {published data only}
  • Luque-de Leon E, Tsiotos GG, Balsiger B, Barnwell J, Burgart LJ, Sarr MG. Staging laparoscopy for pancreatic cancer should be used to select the best means of palliation and not only to maximize the resectability rate. Journal of Gastrointestinal Surgery 1999;3(2):111-7.
Macutkiewicz 2009 {published data only}
  • Macutkiewicz C, Manu M, Sherlock D, D OR. Platelet-lymphocyte ratio and serum carbohydrate antigen 19-9 levels aid in patient selection for staging laparoscopy in suspected pancreatic malignancy. Pancreatology 2009;9(4):525.
Madsen 1994 {published data only}
  • Madsen MR, Bau Mortensen M, Hovendal C. Explorative laparotomy or laparoscopy in patients with carcinoma of the stomach and pancreas?. Minimally Invasive Therapy 1994;3(5):267-70.
Madsen 1994a {published data only}
  • Madsen MR, Mortensen MB, Hovendal CP. Preoperative laparoscopic evaluation of patients with upper gastrointestinal cancer. Ugeskrift For Laeger 1994;156(34):4810-2.
Maire 2004 {published data only}
  • Maire F, Sauvanet A, Trivin F, Hammel P, O'Toole D, Palazzo L, et al. Staging of pancreatic head adenocarcinoma with spiral CT and endoscopic ultrasonography: An indirect evaluation of the usefulness of laparoscopy. Pancreatology 2004;4(5):436-40.
Maithel 2008 {published data only}
  • Maithel SK, Maloney S, Winston C, Gonen M, D'Angelica MI, DeMatteo RP, et al. Preoperative CA 19-9 and the yield of staging laparoscopy in patients with radiographically resectable pancreatic adenocarcinoma. Annals of Surgical Oncology 2008;15(12):3512-20.
Meduri 1994 {published data only}
  • Maffei Faccioli A, Meduri F, Caldironi MW, Diana F, Losacco L, Merenda R, et al. The role of laparoscopy and peritoneal cytology in the preoperative staging of pancreatic carcinoma. Chirurgia Italiana 1994;46(2):26-9.
  • Meduri F, Diana F, Merenda R, Caldironi MW, Zuin A, Losacco L, et al. Implication of laparoscopy and peritoneal cytology in the staging of early pancreatic cancer. Zentralblatt für Pathologie 1994; Vol. 140, issue 3:243-6.
Metcalfe 2003 {published data only}
Meyer 1973 {published data only}
  • Meyer Burg J, Ziegler U, Kirstaedter HJ, Palme G. Peritoneoscopy in carcinoma of the pancreas. Report of 20 cases. Endoscopy 1973;5(2):86-90.
Misra 2012 {published data only}
  • Misra N, Battersby C, Staettner S, Grimes N, McChesney E, Poston G, et al. The role of laparoscopy and tumour biomarkers in potentially resectable hepatobiliary disease; experience from a regional hepatobiliary centre. HPB 2012;14:555-6.
Molnar 2010 {published data only}
  • Molnar G, Iancu C, Munteanu D, Muntean V, Al Hajjarz N, Bala O, et al. The role of diagnostic laparoscopy in periampullary and pancreatic cancers. A study based on 27 cases. Chirurgia 2010;105(3):383-6.
Morak 2009 {published data only}
  • Morak MJ, Hermans JJ, Smeenk HG, Renders WM, Nuyttens JJ, Kazemier G, et al. Staging for locally advanced pancreatic cancer. European Journal of Surgical Oncology 2009;35(9):963-8.
Morganti 2005 {published data only}
  • Morganti AG, Brizi MG, Macchia G, Sallustio G, Costamagna G, Alfieri S, et al. The prognostic effect of clinical staging in pancreatic adenocarcinoma. Annals of Surgical Oncology 2005;12(2):145-51.
Mortensen 1996 {published data only}
  • Mortensen MB, Scheel-Hincke JD, Madsen MR, Qvist N, Hovendal C. Combined endoscopic ultrasonography and laparoscopic ultrasonography in the pretherapeutic assessment of resectability in patients with upper gastrointestinal malignancies. Scandinavian Journal of Gastroenterology 1996;31(11):1115-9.
Muntean 2009 {published data only}
  • Muntean V, Oniu T, Lungoci C, Fabian O, Munteanu D, Molnar G, et al. Staging Laparoscopy in Digestive Cancers. Journal of Gastrointestinal & Liver Diseases 2009;18(4):461-7.
Munteanu 2010 {published data only}
  • Munteanu D, Iancu C, Munteanu A, Muntean V, Molnar G, Mocan T, et al. Is staging laparoscopy in radiologically resectable pancreatic tumours still useful?. European Journal of Surgical Oncology 2010;36(9):899.
Murugiah 1993 {published data only}
  • Murugiah M, Paterson-Brown S, Windsor JA, Miles WF, Garden OJ. Early experience of laparoscopic ultrasonography in the management of pancreatic carcinoma. Surgical Endoscopy 1993;7(3):177-81.
Nagy 1999 {published data only}
  • Nagy A, Pardavi G, Olah A. The role of diagnostic laparoscopy in staging of pancreatic cancers. Acta chirurgica Hungarica 1999;38(2):193-6.
Nieveen 1996 {published data only}
  • Nieveen van Dijkum EJ, Romijn MG, Terwee CB, van der Meulen JH, de Haes JC, de Wit LT, et al. Value of laparoscopic staging and palliative treatment of peri-ampullary tumors; the Stentby Study. Nederlands Tijdschrift Voor Geneeskunde 1996;140(50):2523-4.
Nieveen 1997 {published data only}
Nieveen 1998 {published data only}
  • Nieveen van Dijkum EJ, Sturm PD, de Wit LT, Offerhaus J, Obertop H, Gouma DJ. Cytology of peritoneal lavage performed during staging laparoscopy for gastrointestinal malignancies: is it useful?. Annals of Surgery 1998;228(6):728-33.
Nieveen 1999 {published data only}
  • Nieveen van Dijkum EJ, de Wit LT, van Delden OM, Kruyt PM, van Lanschot JJ, Rauws EA, et al. Staging laparoscopy and laparoscopic ultrasonography in more than 400 patients with upper gastrointestinal carcinoma. Journal of the American College of Surgeons 1999;189(5):459-65.
Nieveen 2000 {published data only}
  • Nieveen van Dijkum EJM, Romijn MG, Terwee CB, de Wit LT, van der Meulen JHP, Bossuyt PMM, et al. Randomised study of laparoscopy and laparoscopic ultrasonography(LLU) for periampullary tumors: Effect on staging and treatment. European of Journal of Gastroenterology & Hepatology 2000;12:A51.
Nieveen 2003 {published data only}
  • Nieveen Van Dijkum EJM, Romijn MG, Terwee CB, De Wit L, Van Der Meulen JHP, Lameris JS, et al. Laparoscopic staging in patients with a peripancreatic tumour is of limited value for diagnosis and palliative treatment. Nederlands Tijdschrift Voor Geneeskunde 2003;147(36):1734-40.
Nieveen 2003a {published data only}
  • Nieveen van Dijkum EJM, Romijn MG, Terwee CB, de Wit LT, Van der Meulen JHP, Lameris HS, et al. Laparoscopic staging and subsequent palliation in patients with peripancreatic carcinoma. Annals of Surgery 2003;237(1):66-73.
Occelli 1999 {published data only}
  • Occelli G, Feroce A, Barrat C, Catheline JM, Champault G. Staging of pancreatic cancer by laparoscopy and laparoscopic ultrasonography. Chirurgia 1999;12(5):379-87.
Palanivelu 2001 {published data only}
  • Palanivelu C, Rajan PS, Kumar SK, Parthasarathi R. Role of laparoscopy in pancreatic surgery. Journal International Medical Sciences Academy 2001;14(3):137-9.
Parks 2000 {published data only}
  • Parks RW, Garden OJ. Staging laparoscopy for pancreatic carcinoma: Can it be cost effective?. Asian Journal of Surgery 2000;23(3):187-90.
Pedrazzoli 1994 {published data only}
  • Pedrazzoli S, Sperti C, Pasquali C. Prediction of resectability and of surgical risk in pancreatic carcinoma; conditioning factors of survival after resective intervention. Chirurgia Italiana 1994;46(2):30-8.
Pelton 1998 {published data only}
Pietrabissa 1996 {published data only}
  • Pietrabissa A, Di Candio G, Giulianotti PC, Carobbi A, Boggi U, Mosca F. Operative technique for the laparoscopic staging of pancreatic malignancy. Minimally Invasive Therapy & Allied Technologies 1996;5(3):274-80.
Pietrabissa 1996a {published data only}
  • Pietrabissa A, Di Candio G, Giulianotti PC, Mosca F. Laparoscopic exposure of the pancreas and staging of pancreatic cancer. Seminars in Laparoscopic Surgery 1996;3(1):3-9.
Pietrabissa 1999 {published data only}
  • Pietrabissa A, Caramella D, Di Candio G, Carobbi A, Boggi U, Rossi G, et al. Laparoscopy and laparoscopic ultrasonography for staging pancreatic cancer: Critical appraisal. World Journal of Surgery 1999;23(10):998-1003.
Pisters 2001 {published data only}
Potkonjak 1974 {published data only}
  • Potkonjak D, Filipovic Ristic B, Bjelic J. Comparison of laparoscopic, surgical and histologic findings in the diagnosis of malignant tumors of the pancreas. Medicinski Arhiv 1974;28(2):195-8.
Ramshaw 1999 {published data only}
Ribero 1994 {published data only}
  • Ribero F, Comotti F, Scaglia M, Ragusa L. Diagnostic-operative laparoscopy. Our experience. Minerva Chirurgica 1994;49(6):533-7.
Rodgers 2003 {published data only}
  • Rodgers MS, Windsor JA, Koea JB, McCall JL. Laparoscopic staging of upper gastrointestinal malignancy. ANJ Journal of Surgery 2003;73(10):806-10.
Rothlin 1996 {published data only}
  • Röthlin M. Diagnostic laparoscopy and laparoscopic ultrasonography: value of staging and assessment of resectability of pancreatic carcinoma [Diagnostische laparoskopie und laparoskopische sonographie: stellenwert fur staging und resektabilitatsabklarung beim pankreaskarzinom]. Swiss Surgery 1996;Suppl 4:25-8.
Rumstadt 1997 {published data only}
  • Rumstadt B, Schwab M, Schuster K, Hagmuller E, Trede M. The role of laparoscopy in the preoperative staging of pancreatic carcinoma. Journal of Gastrointestinal Surgery 1997;1(3):245-50.
Rumstadt 1997a {published data only}
  • Rumstadt B, Trede M. The role of laparoscopy and ultrafast magnetic resonance imaging in the preoperative staging of pancreatic carcinoma. Problems in General Surgery 1997;14(2):59-64.
Saeian 1999 {published data only}
Sand 1996 {published data only}
  • Sand J, Marnela K, Airo I, Nordback I. Staging of abdominal cancer by local anesthesia outpatient laparoscopy. Hepatogastroenterology 1996;43(12):1685-8.
Santoro 2012 {published data only}
  • Santoro PM, Abdel-Misih RZ, Petrelli NJ, Bennett JJ. Is laparoscopy still needed for staging "resectable" pancreatic cancer?. Annals of Surgical Oncology 2012;19:S162.
Sato 1985 {published data only}
  • Sato W. Laparoscopic biopsy of the pancreas. Gastroenterological Endoscopy 1985;27(10):1940-9.
Satoi 2011 {published data only}
  • Satoi S, Yanagimoto H, Toyokawa H, Inoue K, Wada K, Yamamoto T, et al. Selective use of staging laparoscopy based on carbohydrate antigen 19-9 level and tumor size in patients with radiographically defined potentially or borderline resectable pancreatic cancer. Pancreas 2011;40(3):426-32.
Schachter 1999 {published data only}
  • Schachter P, Avni Y, Rosen A, Czerniak A. Evaluation of laparoscopy and laparoscopic ultrasound in diagnosis and treatment of pancreatic lesions. Harefuah 1999;137(12):593-7, 680.
Schmidt 1997 {published data only}
  • Schmidt J, Zirngibl H, Heinmoller E, Schuckel E, Jauch KW. Laparoscopy and intraoperative peritoneal cytology as predictors of operability in pancreatic carcinoma. Acta Chirurgica Austriaca 1997;29(2):90-4.
Schmied 2000 {published data only}
  • Schmied BM, Z'Graggen K, Redaelli CA, Buchler MW. Problems in staging of pancreatic and hepatobiliary tumours. Annals of Oncology 2000;11 Suppl 3:161-4.
Schmielau 1997 {published data only}
Schneider 2003 {published data only}
  • Schneider AR, Adamek HE, Layer G, Riemann JF, Arnold JC. Staging of abdominal metastases in pancreatic carcinoma by diagnostic laparoscopy and magnetic resonance imaging. Zeitschrift für Gastroenterologie 2003;41(8):697-702.
Schrenk 1994 {published data only}
Schrenk 1995 {published data only}
Schwab 1996 {published data only}
  • Schwab M, Schwall G, Richter A, Trede M. Is diagnostic laparoscopy a reliable addition to preoperative staging of pancreatic carcinoma?. Langenbecks Archiv für Chirurgie. Supplement. Kongressband 1996;113:565-7.
Sperlongano 2005 {published data only}
  • Sperlongano P, Avenia N. Does laparoscopy have a role in pancreatic cancer?. Il Giornale di Chirurgia 2005;26(8-9):293-4.
Sperlongano 2006 {published data only}
Tang 2001 {published data only}
  • Tang CN, Siu WT, Li MKW. Use of diagnostic laparoscopy and laparoscopic ultrasound in the management of upper gastrointestinal malignancy. Annals of the College of Surgeons of Hong Kong 2001;5(1):19-24.
Tapper 2011 {published data only}
Taylor 2001 {published data only}
Terrosu 2000 {published data only}
  • Terrosu G, Cedolini C, Baccarani U, Vianello V, Bruschi F, Uzzau A, et al. Echolaparoscopy in the staging of abdominal neoplasms. Prospective study. Annali Italiani di Chirurgia 2000;71(2):199-204.
Thomson 2006 {published data only}
  • Thomson BN, Parks RW, Redhead DN, Welsh FK, Madhavan KK, Wigmore SJ, et al. Refining the role of laparoscopy and laparoscopic ultrasound in the staging of presumed pancreatic head and ampullary tumours. British Journal of Cancer 2006;94(2):213-7.
Tilleman 2004 {published data only}
  • Tilleman EH, Busch OR, Bemelman WA, van Gulik TM, Obertop H, Gouma DJ. Diagnostic laparoscopy in staging pancreatic carcinoma: developments during the past decade. Journal of Hepato-Biliary-Pancreatic Surgery 2004;11(1):11-6.
Tilleman 2004a {published data only}
  • Tilleman EH, Kuiken BW, Phoa SS, de Castro SM, Busch OR, Obertop H, et al. Limitation of diagnostic laparoscopy for patients with a periampullary carcinoma. European Journal of Surgical Oncology 2004;30(6):658-62.
van Delden 1996 {published data only}
  • van Delden OM, Smits NJ, Bemelman WA, de Wit LT, Gouma DJ, Reeders JW. Comparison of laparoscopic and transabdominal ultrasonography in staging of cancer of the pancreatic head region. Journal of Ultrasound in Medicine 1996;15(3):207-12.
van Dijkum 1997 {published data only}
Velanovich 1998 {published data only}
Velanovich 2004 {published data only}
Velasco 2000 {published data only}
  • Velasco JM, Rossi H, Hieken TJ, Fernandez M. Laparoscopic ultrasound enhances diagnostic laparoscopy in the staging of intra-abdominal neoplasms. American Surgeon 2000;66(4):407-11.
Vollmer 2002 {published data only}
  • Vollmer CM, Drebin JA, Middleton WD, Teefey SA, Linehan DC, Soper NJ, et al. Utility of staging laparoscopy in subsets of peripancreatic and biliary malignancies. Annals of Surgery 2002;235(1):1-7.
Warshaw 1990 {published data only}
  • Warshaw AL, Gu ZY. Laparoscopy for preoperative staging of malignant tumors of the foregut. Esophageal, gastric, and pancreatic cancer. Problems in General Surgery 1990;7(Special Issue):65-74.
Warshaw 1990a {published data only}
Watanabe 1993 {published data only}
Weiner 1995 {published data only}
White 2001 {published data only}
  • White RR, Paulson EK, Freed KS, Keogan MT, Hurwitz HI, Lee C, et al. Staging of pancreatic cancer before and after neoadjuvant chemoradiation. Journal of Gastrointestinal Surgery 2001;5(6):626-33.
White 2004 {published data only}
White 2008 {published data only}
  • White R, Winston C, Gonen M, D'Angelica M, Jarnagin W, Fong Y, et al. Current utility of staging laparoscopy for pancreatic and peripancreatic neoplasms. Journal of the American College of Surgeons 2008;206(3):445-50.
Wilson 2010 {published data only}
Yoshida 2002 {published data only}
  • Yoshida T, Matsumoto T, Morii Y, Ishio T, Kitano S, Yamada Y, et al. Staging with helical computed tomography and laparoscopy in pancreatic head cancer. Hepatogastroenterology 2002;49(47):1428-31.
Zhao 2003 {published data only}
  • Zhao ZW, He JY, Tan G, Wang HJ, Li KJ. Laparoscopy and laparoscopic ultrasonography in judging the resectability of pancreatic head cancer. Hepatobiliary & Pancreatic Diseases International 2003;2(4):609-11.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Abrams 2009
  • Abrams RA, Lowy AM, O'Reilly EM, Wolff RA, Picozzi VJ, Pisters PW. Combined modality treatment of resectable and borderline resectable pancreas cancer: Expert consensus statement. Annals of Surgical Oncology 2009;16(7):1751-6.
Azevedo 2009
  • Azevedo JL, Azevedo OC, Miyahira SA, Miguel GP, Becker OM Jr, Hypolito OH, et al. Injuries caused by Veress needle insertion for creation of pneumoperitoneum: a systematic literature review. Surgical Endoscopy 2009;23(7):1428-32.
Chang 2009
  • Chang L, Stefanidis D, Richardson WS, Earle DB, Fanelli RD. The role of staging laparoscopy for intraabdominal cancers: an evidence-based review. Surgical Endoscopy 2009;23(2):231-41.
Conlon 1996
  • Conlon KC, Klimstra DS, Brennan MF. Long-term survival after curative resection for pancreatic ductal adenocarcinoma. Clinicopathologic analysis of 5-year survivors. Annals of Surgery 1996;223(3):273-9.
Eloubeidi 2001
  • Eloubeidi MA, Wade SB, Provenzale D. Factors associated with acceptance and full publication of GI endoscopic research originally published in abstract form. Gastrointestinal Endoscopy 2001;53(3):275-82.
Engelken 2003
Gurusamy 2013
  • Gurusamy KS, Davidson BR. Diagnostic accuracy of different imaging modalities for assessing the resectability in pancreatic and periampullary cancer. Cochrane Database of Systematic Reviews 2011.
Klempnauer 1995
Lillemoe 1999
  • Lillemoe KD, Cameron JL, Hardacre JM, Sohn TA, Sauter PK, Coleman J, et al. Is prophylactic gastrojejunostomy indicated for unresectable periampullary cancer? A prospective randomized trial. Annals of Surgery 1999;230(3):322-8.
Mayo 2009
  • Mayo SC, Austin DF, Sheppard BC, Mori M, Shipley DK, Billingsley KG. Evolving preoperative evaluation of patients with pancreatic cancer: does laparoscopy have a role in the current era?. Journal of the American College of Surgeons 2009;208(1):87-95.
Michelassi 1989
  • Michelassi F, Erroi F, Dawson PJ, Pietrabissa A, Noda S, Handcock M, et al. Experience with 647 consecutive tumors of the duodenum, ampulla, head of the pancreas, and distal common bile duct. Annals of Surgery 1989;210(4):544-54.
National Cancer Institute 2011a
  • National Cancer Institute (U.S. National Institute of Health). Dictionary of Cancer terms. Periampullary cancer. http://www.cancer.gov/dictionary/?CdrID=543930 accessed on 17/04/2011.
National Cancer Institute 2011b
  • National Cancer Institute (U.S. National Institute of Health). Dictionary of Cancer terms. Periampullary cancer. http://www.cancer.gov/dictionary?CdrID=46033 accessed on 17/04/2011.
Reitsma 2005
  • Reitsma JB, Glas AS, Rutjes AWS, Scholten RJPM, Bossuyt PM, Zwinderman AH. Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. Journal of Clinical Epidemiology 2005;58(10):982-90.
Sampson 2008
  • Sampson M, Shojania KG, McGowan J, Daniel R, Rader T, Iansavichene AE, et al. Surveillance search techniques identified the need to update systematic reviews. Journal of Clinical Epidemiology 2008;61(8):755-62.
Shahrudin 1997
Smith 2008
  • Smith RA, Bosonnet L, Ghaneh P, Sutton R, Evans J, Healey P, et al. The platelet-lymphocyte ratio improves the predictive value of serum CA19-9 levels in determining patient selection for staging laparoscopy in suspected periampullary cancer. Surgery 2008;143(5):658-66.
Whiting 2006
  • Whiting PF, Weswood ME, Rutjes AW, Reitsma JB, Bossuyt PN, Kleijnen J. Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies. BMC Medical Research Methodology. 2006/03/08 2006; Vol. 6:9.
Whiting 2011
  • Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Annals of Internal Medicine 2011;155(8):529-36.
Yeo 2002
  • Yeo CJ, Cameron JL, Lillemoe KD, Sohn TA, Campbell KA, Sauter PK, et al. Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma, part 2: randomized controlled trial evaluating survival, morbidity, and mortality. Annals of Surgery 2002;236(3):355-66.