Chemotherapy for downstaging unresectable liver metastases from colorectal cancer

  • Protocol
  • Intervention



This is the protocol for a review and there is no abstract. The objectives are as follows:

We will determine the optimal chemotherapy regimen for downstaging patients with inoperable colorectal liver metastases.

In those patients successfully downstaged by chemotherapy we will determine what effect chemotherapy has on the hepatic parenchyma and its impact on perioperative morbidity and mortality.