Intervention Review

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Zinc supplements for treating thalassaemia and sickle cell disease

  1. Kye Mon Min Swe1,*,
  2. Adinegara BL Abas1,
  3. Amit Bhardwaj2,
  4. Ankur Barua3,
  5. N S Nair4

Editorial Group: Cochrane Cystic Fibrosis and Genetic Disorders Group

Published Online: 28 JUN 2013

Assessed as up-to-date: 20 JUN 2013

DOI: 10.1002/14651858.CD009415.pub2

How to Cite

Swe KMM, Abas ABL, Bhardwaj A, Barua A, Nair NS. Zinc supplements for treating thalassaemia and sickle cell disease. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD009415. DOI: 10.1002/14651858.CD009415.pub2.

Author Information

  1. 1

    Melaka-Manipal Medical College (MMMC), Department of Community Medicine, Melaka, Malaysia

  2. 2

    Melaka-Manipal Medical College (MMMC), Department of Orthopaedics, Melaka, Melaka, Malaysia

  3. 3

    International Medical University (IMU), Department of Community Medicine, Kuala Lumpur, Malaysia

  4. 4

    Manipal University, Department of Statistics, Manipal, Karnataka, India

*Kye Mon Min Swe, Department of Community Medicine, Melaka-Manipal Medical College (MMMC), Jalan Batu Hampar, Bukit Baru, Melaka, 75150, Malaysia. khmoneminswe@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 28 JUN 2013

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[Figure 1]
Figure 1. Study flow diagram
[Figure 2]
Figure 2. Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Figure 3]
Figure 3. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Zinc versus placebo (thalassaemia), Outcome 1 Serum zinc level.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Zinc versus placebo (thalassaemia), Outcome 2 Body mass index.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Zinc versus placebo (thalassaemia), Outcome 3 Height velocity.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 1 Haemoglobin.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 2 Serum zinc level.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 3 Serum zinc level.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 4 Body mass index.
[Analysis 2.5]
Analysis 2.5. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 5 Weight.
[Analysis 2.6]
Analysis 2.6. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 6 Sickle cell crisis.
[Analysis 2.7]
Analysis 2.7. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 7 Total number of infection.
[Analysis 2.8]
Analysis 2.8. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 8 Total number of infection.
[Analysis 2.9]
Analysis 2.9. Comparison 2 Zinc versus placebo (sickle cell disease), Outcome 9 Improvement in leg ulcer.