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Naproxen with or without an antiemetic for acute migraine headaches in adults

  1. Simon Law1,
  2. Sheena Derry2,*,
  3. R Andrew Moore2

Editorial Group: Cochrane Pain, Palliative and Supportive Care Group

Published Online: 20 OCT 2013

Assessed as up-to-date: 22 MAY 2013

DOI: 10.1002/14651858.CD009455.pub2


How to Cite

Law S, Derry S, Moore RA. Naproxen with or without an antiemetic for acute migraine headaches in adults. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD009455. DOI: 10.1002/14651858.CD009455.pub2.

Author Information

  1. 1

    Gloucester Hospitals NHS Foundation Trust, Department of Anaesthetics, Gloucestershire, UK

  2. 2

    University of Oxford, Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), Oxford, Oxfordshire, UK

*Sheena Derry, Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, OX3 7LE, UK. sheena.derry@ndcn.ox.ac.uk.

Publication History

  1. Publication Status: Stable (no update expected for reasons given in 'What's new')
  2. Published Online: 20 OCT 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
Brandes 2007 Study 1 {published data only}
  • Brandes JL, Kudrow D, Stark SR, O'Carroll CP, Adelman JU, O'Donnell FJ, et al. Sumatriptan-naproxen for acute treatment of migraine: a randomized trial. JAMA 2007;297(13):1443-54. [DOI: 10.1001/jama.297.13.1443]
  • Landy S, DeRossett SE, Rapoport A, Rothrock J, Ames MH, McDonald SA, et al. Two double-blind, multicenter, randomized, placebo-controlled, single-dose studies of sumatriptan/naproxen sodium in the acute treatment of migraine: function, productivity, and satisfaction outcomes. Medscape General Medicine 2007;9(2):53.
Brandes 2007 Study 2 {published data only}
  • Brandes JL, Kudrow D, Stark SR, O'Carroll CP, Adelman JU, O'Donnell FJ, et al. Sumatriptan-naproxen for acute treatment of migraine: a randomized trial. JAMA 2007;297(13):1443-54. [DOI: 10.1001/jama.297.13.1443]
  • Landy S, DeRossett SE, Rapoport A, Rothrock J, Ames MH, McDonald SA, et al. Two double-blind, multicenter, randomized, placebo-controlled, single-dose studies of sumatriptan/naproxen sodium in the acute treatment of migraine: function, productivity, and satisfaction outcomes. Medscape General Medicine 2007;9(2):53.
S2WA4003 {published data only}
  • Anonymous. A randomized, double-blind, double-dummy, active-placebo controlled, parallel group evaluation of oral naratriptan (2.5mg) compared to oral naproxen sodium (275mg) on migraine-related quality of life. Result summary for S2WA4003. download.gsk-clinicalstudyregister.com/files/2014.pdf (accessed 19 September 2013).
S2WA4004 {published data only}
  • Anonymous. A randomized, double-blind, double-dummy, active-placebo controlled, parallel group evaluation of oral naratriptan (2.5mg) compared to oral naproxen sodium (275mg) on migraine-related quality of life. Result summary for S2WA4004. download.gsk-clinicalstudyregister.com/files/2041.pdf (accessed 19 September 2013).
Smith 2005 {published data only}
Wentz 2008 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
Adis 2006 {published data only}
  • Adis International Limited. Naproxen sodium/metoclopramide: metoclopramide/naproxen-sodium, MT 100, naproxen-sodium/metoclopramide. Drugs in R and D 2006;7(4):259-61.
Andersson 1989 {published data only}
Johnson 1985 {published data only}
Krymchantowski 2005 {published data only}
  • Krymchantowski AV, Peixoto P, Higashi R, Silva A Jr, Schutz V. Lysine clonixinate vs naproxen sodium for the acute treatment of migraine: a double-blind, randomized, crossover study. Medscape General Medicine 2005;7(4):69.
Misra 2010 {published data only}
  • Misra M, Sharma T, Kalra J, Goel D, Dhasmana DC. Comparative efficacy and tolerability of sumatriptan, ergotamine, naproxen and rizatriptan in moderate to severe acute attack of migraine. JK Science 2010;12(4):175-9.
NCT01726920 {published data only}
  • Peron C. Efficacy and safety of a fixed-dose combination of naratriptan and naproxen in acute treatment of migraine (Copérnico). clinicaltrials.gov/show/NCT01726920 (accessed 19 September 2013). [ACH-NRP-03(04/12)]
Nestvold 1985 {published data only}
Nestvold 1986 {published data only}
Pradalier 1985 {published data only}
Sargent 1988 {published data only}
Smith 2007 {published data only}
Stronks 2003 {published data only}
Treves 1992 {published data only}
Welch 1986 {published data only}

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
NCT01390324 {published data only}
  • Peron C. Efficacy and safety of a fixed-dose combination of naratriptan and naproxen in acute treatment of migraine (Atenéia). clinicaltrials.gov/show/NCT01390324 (accessed 19 September 2013). [ACH-NRP-03(05/11)]

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
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Derry 2012
  • Derry C, Derry S, Moore A. Sumatriptan (oral route of administration) for acute migraine attacks in adults. Cochrane Database of Systematic Reviews 2012;2:CD008615. [DOI: 10.1002/14651858.CD008615.pub2]
Derry 2013
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