This is the protocol for a review and there is no abstract. The objectives are as follows:
The objective of this review is to determine the effect of vapocoolants on pain associated with intravenous cannulation in adults and children. Conditions that may affect the performance of the vapocoolants will be explored including length of application, distance from the skin and time to cannulation. The review will also look at any adverse effects associated with the use of vapocoolants.