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Specially formulated foods for treating children with moderate acute malnutrition in low- and middle-income countries

  1. Marzia Lazzerini*,
  2. Laura Rubert,
  3. Paola Pani

Editorial Group: Cochrane Developmental, Psychosocial and Learning Problems Group

Published Online: 21 JUN 2013

Assessed as up-to-date: 24 APR 2013

DOI: 10.1002/14651858.CD009584.pub2


How to Cite

Lazzerini M, Rubert L, Pani P. Specially formulated foods for treating children with moderate acute malnutrition in low- and middle-income countries. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD009584. DOI: 10.1002/14651858.CD009584.pub2.

Author Information

  1. WHO Collaborating Centre for Maternal and Child Health, Institute for Maternal and Child Health, Unit for Health Services Research and International Health, Trieste, Italy

*Marzia Lazzerini, Unit for Health Services Research and International Health, WHO Collaborating Centre for Maternal and Child Health, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, 8232, Italy. lazzerini@burlo.trieste.it.

Publication History

  1. Publication Status: New
  2. Published Online: 21 JUN 2013

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[Figure 1]
Figure 1. Study flow diagram
[Figure 2]
Figure 2. Risk of bias summary: review authors' judgements about each risk of bias item for each included study
[Figure 3]
Figure 3. Forest plot of comparison: 1 Specially formulated foods vs Standard care, outcome: 1.1 Recovery
[Figure 4]
Figure 4. Forest plot of comparison: 2 Lipid-based nutrient supplements vs Blended foods, outcome: 2.1 Recovery
[Analysis 1.1]
Analysis 1.1. Comparison 1 Specially formulated foods vs Standard care, Outcome 1 Recovered.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Specially formulated foods vs Standard care, Outcome 2 Not recovered.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Specially formulated foods vs Standard care, Outcome 3 Progression to SAM.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Specially formulated foods vs Standard care, Outcome 4 Died.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Specially formulated foods vs Standard care, Outcome 5 Defaulted.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Specially formulated foods vs Standard care, Outcome 6 Weight gain (total, kg).
[Analysis 1.7]
Analysis 1.7. Comparison 1 Specially formulated foods vs Standard care, Outcome 7 WHZ (final, z-scores).
[Analysis 1.8]
Analysis 1.8. Comparison 1 Specially formulated foods vs Standard care, Outcome 8 WHZ gain (total, z-scores).
[Analysis 1.9]
Analysis 1.9. Comparison 1 Specially formulated foods vs Standard care, Outcome 9 MUAC gain (total, mm).
[Analysis 1.10]
Analysis 1.10. Comparison 1 Specially formulated foods vs Standard care, Outcome 10 Height gain (total, mm).
[Analysis 1.11]
Analysis 1.11. Comparison 1 Specially formulated foods vs Standard care, Outcome 11 HAZ (final, z-scores).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 1 Recovered.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 2 Not recovered.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 3 Progression to SAM.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 4 Died.
[Analysis 2.5]
Analysis 2.5. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 5 Defaulted.
[Analysis 2.6]
Analysis 2.6. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 6 Weight gain (g/kg/day).
[Analysis 2.7]
Analysis 2.7. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 7 WHZ (final, z-scores).
[Analysis 2.8]
Analysis 2.8. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 8 WHZ gain (total, z-scores).
[Analysis 2.9]
Analysis 2.9. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 9 MUAC gain (mm/day).
[Analysis 2.10]
Analysis 2.10. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 10 Adverse effect: vomit (first 2 weeks).
[Analysis 2.11]
Analysis 2.11. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 11 Adverse effect: diarrhoea (first 2 weeks).
[Analysis 2.12]
Analysis 2.12. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 12 Adverse effect: adverse reactions.
[Analysis 2.13]
Analysis 2.13. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 13 Height gain (mm/day).
[Analysis 2.14]
Analysis 2.14. Comparison 2 Lipid-based nutrient supplements vs any Blended foods, Outcome 14 HAZ (final, z-scores).
[Analysis 3.1]
Analysis 3.1. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 1 Recovered.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 2 Not recovered.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 3 Progression to SAM.
[Analysis 3.4]
Analysis 3.4. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 4 Died.
[Analysis 3.5]
Analysis 3.5. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 5 Defaulted.
[Analysis 3.6]
Analysis 3.6. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 6 Weight gain (g/kg/day).
[Analysis 3.7]
Analysis 3.7. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 7 WHZ (final, z-scores).
[Analysis 3.8]
Analysis 3.8. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 8 WHZ gain (total, kg).
[Analysis 3.9]
Analysis 3.9. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 9 MUAC gain (mm/day).
[Analysis 3.10]
Analysis 3.10. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 10 Adverse effect: vomiting (first 2 weeks).
[Analysis 3.11]
Analysis 3.11. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 11 Adverse effect: diarrhoea (first 2 weeks).
[Analysis 3.12]
Analysis 3.12. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 12 Adverse effect: adverse reactions.
[Analysis 3.13]
Analysis 3.13. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 13 Height gain (mm/day).
[Analysis 3.14]
Analysis 3.14. Comparison 3 Lipid-based nutrient supplements vs specific types of Blended foods, Outcome 14 HAZ (final, z-scores).
[Analysis 4.1]
Analysis 4.1. Comparison 4 CSB++ vs other Blended foods, Outcome 1 Recovered.
[Analysis 4.2]
Analysis 4.2. Comparison 4 CSB++ vs other Blended foods, Outcome 2 Died.
[Analysis 4.3]
Analysis 4.3. Comparison 4 CSB++ vs other Blended foods, Outcome 3 Weight gain (total, kg).
[Analysis 5.1]
Analysis 5.1. Comparison 5 Subgroup analysis: Lipid-based nutrient supplements (full dose) vs Blended foods (full dose): Recovery, Outcome 1 Recovered.