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Intervention Review

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Interventions for the management of dry mouth: non-pharmacological interventions

  1. Susan Furness1,*,
  2. Gemma Bryan1,
  3. Roddy McMillan2,
  4. Helen V Worthington1

Editorial Group: Cochrane Oral Health Group

Published Online: 30 AUG 2013

Assessed as up-to-date: 16 APR 2013

DOI: 10.1002/14651858.CD009603.pub2


How to Cite

Furness S, Bryan G, McMillan R, Worthington HV. Interventions for the management of dry mouth: non-pharmacological interventions. Cochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD009603. DOI: 10.1002/14651858.CD009603.pub2.

Author Information

  1. 1

    School of Dentistry, The University of Manchester, Cochrane Oral Health Group, Manchester, UK

  2. 2

    Eastman Dental Hospital, London, UK

*Susan Furness, Cochrane Oral Health Group, School of Dentistry, The University of Manchester, Coupland III Building, Oxford Rd, Manchester, M13 9PL, UK. Susan.Furness@manchester.ac.uk. suefurness@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 30 AUG 2013

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This is not the most recent version of the article. View current version (05 SEP 2013)

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Blom 1992 {published data only}
Blom 1996 {published data only}
  • Blom M, Dawidson I, Angmar-Månsson B, Johnson G. Effect of acupuncture on salivary flow in subjects with radiation-induced xerostomia. Caries Research 1993;27:225.
  • Blom M, Dawidson I, Fernberg JO, Johnson G, Angmar-Månsson B. Acupuncture treatment of patients with radiation-induced xerostomia. Oral Oncology, European Journal of Cancer 1996;32B(3):182-90.
Cho 2008 {published data only}
  • Cho JH, Chung WK, Kang W, Choi SM, Cho CK, Son CG. Manual acupuncture improved quality of life in cancer patients with radiation-induced xerostomia. The Journal of Alternative and Complementary Medicine 2008;14(5):523-6.
List 1998 {published data only}
  • List T, Lundeberg T, Lundström I, Lindström F, Ravald N. The effect of acupuncture in the treatment of patients with primary Sjögren's syndrome. Acta Odontologica Scandinavica 1998;56:95-9.
Papas 2006 {published data only}
  • Papas A, Singh M, Harrington D, Rodriguez S, Ortblad K, de Jager M, et al. Stimulation of salivary flow with powered toothbrush in a xerostomic population. Special Care Dentistry 2006;26(6):241-6.
Pfister 2010 {published data only}
  • Pfister DG, Cassileth BR, Deng GE, Yeung KS, Lee JS, Garrity D, et al. Acupuncture for pain and dysfunction after neck dissection: results of a randomized controlled trial. Journal of Clinical Oncology 2010;28(15):2565-70. [PUBMED: 20406930]
Steller 1988 {published data only}
Talal 1992 {published data only}
  • Talal N, Quinn JH, Daniels TE. The clinical effects of electrostimulation on salivary function of Sjögren's syndrome patients: a placebo controlled trial. Rheumatology International 1992;12:43-5.
Wong 2003 {published data only}
  • Wong R, Sagar S, Whelan T, Foster G, Farges-Babjak A, Willan A, et al. The use of acupuncture-like transcutaneous nerve stimulation (CODETRON) in the treatment of radiation-induced xerostomia in head and neck cancer patients treated with radical radiotherapy. International Journal of Radiation, Oncology, Biology, and Physics 2011;51:2351.
  • Wong RKW, Jones GW, Sagar SM, Babjak A-F, Whelan T. A phase I-II study in the use of acupuncture-like transcutaneous nerve stimulation in the treatment of radiation-induced xerostomia in head-and-neck cancer patients treated with radical radiotherapy. International Journal of Radiation, Oncology, Biology and Physics 2003;57(2):472-80.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Blom 2000 {published data only}
  • Blom M, Lundeberg T. Long-term follow-up of patients treated with acupuncture for xerostomia and the influence of additional treatment. Oral Diseases 2000;6(1):15-24. [PUBMED: 10673783]
Braga 2011 {published data only}
  • Braga FP, Lemos Junior CA, Alves FA, Migliari DA. Acupuncture for the prevention of radiation-induced xerostomia in patients with head and neck cancer. Brazilian Oral Research 2011;25(2):180-5. [PUBMED: 21537645]
  • Braga FPF, Migliari DA. Acupuncture for prevention of radiation-induced xerostomia. Oral Diseases 2010;16(6):539 (Abs No 104).
Cheville 2006 {published data only}
  • Cheville AM, Basford JR. Home based acupuncture: a study in xerostomia. Focus on Alternative and Complementary Therapies 2006;11(Suppl 1):10-1.
Deng 2008 {published data only}
  • Deng G, Hou BL, Holodny AI, Cassileth BR. Functional magnetic resonance imaging (fMRI) changes and saliva production associated with acupuncture at LI-2 acupuncture point: a randomized controlled study. BMC Complementary and Alternative Medicine 2008;8:37. [PUBMED: 18606019]
Fontanesi 1991 {published data only}
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Garcia 2009 {published data only}
Loncar 2011 {published data only}
  • Loncar B, Stipetic MM, Baricevic M, Risovic D. The effect of low-level laser therapy on salivary glands in patients with xerostomia. Photomedicine and Laser Surgery 2011;29(3):171-5. [PUBMED: 21054200]
Meng 2012 {published data only}
Niemtzow 2007 {published data only}
  • Niemtzow vonR. Rapid acupuncture treatment for severe dry mouth secondary to radiotherapy, chemotherapy and surgery for head and neck cancer patients [Schnell wirksame akupunktur bei schwerer mundtrockenheit nach bestrahlung, chemotherapie und operation bei kopf und hals carcinomen]. Schmerz und Akupunktur 2007;3:118-22.
Schiff 2009 {published data only}
  • Schiff E, Mogilner JG, Sella E, Doweck I, Hershko O, Ben-Arye E, et al. Hypnosis for postradiation xerostomia in head and neck cancer patients: a pilot study. Journal of Pain and Symptom Management 2009;37(6):1086-92.e1. [PUBMED: 19186028]
Simcock 2009 {published data only}
  • Simcock R, Fallowfield L, Jenkins V. Group acupuncture to relieve radiation induced xerostomia: a feasibility study. Acupuncture in Medicine: Journal of the British Medical Acupuncture Society 2009;27(3):109-13. [PUBMED: 19734380]
Simcock 2013 {published data only}
  • Simcock R, Fallowfield L, Monson K, Ivonne ST, Parlour L, Langridge CI, et al. ARIX: A randomized trial of acupuncture versus oral care sessions in patients with chronic radiation-induced xerostomia following treatment for head and neck cancer. Journal of Clinical Oncology 2012;30(Suppl):Abstract No 5527.
  • Simcock R, Fallowfield L, Monson K, Solis-Trapala I, Parlour L, Langridge C, et al. ARIX: a randomised trial of acupuncture v oral care sessions in patients with chronic xerostomia following treatment of head and neck cancer. Annals of Oncology 2013;24(3):776-83.
Simoes 2010 {published data only}
  • Simoes A, de Campos L, de Souza DN, de Matos JA, Freitas PM, Nicolau J. Laser phototherapy as topical prophylaxis against radiation induced xerostomia. Photomedicine and Laser Surgery 2010;28(3):357-63.
Strietzel 2007 {published data only}
Strietzel 2011 {published data only}
  • Alajbeg I, Falcao DP, Tran SD, Martin-Granizo R, Lafaurie GI, Matranga D, et al. Intraoral electrostimulator for xerostomia relief: a long-term, multicenter, open-label, uncontrolled, clinical trial. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 2012;113(6):773-81. [PUBMED: 22668705]
  • Strietzel FP, Lafaurie GI, Bautista Mendoza GR, Alajbeg I, Pejda S, Vuletić Mantilla R, et al. Efficacy and safety of an intraoral electrostimulation device for xerostomia relief: a multicenter, randomized trial. Arthritis and Rheumatism 2011;63(1):180-90.
Weiss 1986 {published data only}
  • Weiss WW Jr, Brenman HS, Katz P, Bennett JA. Use of an electronic stimulator for the treatment of dry mouth. Journal of Oral and Maxillofacial Surgery 1986;44(11):845-50. [PUBMED: 3490558]
Wong 2010 {published data only}
  • Wong RK, Sagar SM, Chen BJ, Yi GY, Cook R. Phase II randomized trial of acupuncture-like transcutaneous electrical nerve stimulation to prevent radiation-induced xerostomia in head and neck cancer patients. Journal of the Society for Integrative Oncology 2010;8(2):35-42. [PUBMED: 20388444]
Wong 2012 {published data only}
  • Wong RK, James JL, Sagar S, Wyatt G, Nguyen-Tan PF, Singh AK, et al. Phase 2 results from Radiation Therapy Oncology Group Study 0537: a phase 2/3 study comparing acupuncture-like transcutaneous electrical nerve stimulation versus pilocarpine in treating early radiation-induced xerostomia. Cancer 2012;118(17):4244-52.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
NCT01141231 {published data only}
  • MD Anderson Cancer Center. Acupuncture in treating dry mouth caused by radiation therapy in patients with head and neck cancer. Available from ClinicalTrials.gov.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
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  • Fedele S, Wolff A, Strietzel F, Lopez RM, Porter SR, Konttinen YT. Neuroelectrostimulation in treatment of hyposalivation and xerostomia in Sjogren's syndrome: a salivary pacemaker. Journal of Rheumatology 2008;35(8):1489-94.
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Hopcraft 2010
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