Intervention Review

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Interferon after surgery for women with advanced (Stage II-IV) epithelial ovarian cancer

  1. Aramide O Lawal*,
  2. Alfred Musekiwa,
  3. Liesl Grobler

Editorial Group: Cochrane Gynaecological, Neuro-oncology and Orphan Cancer Group

Published Online: 6 JUN 2013

Assessed as up-to-date: 16 MAY 2013

DOI: 10.1002/14651858.CD009620.pub2


How to Cite

Lawal AO, Musekiwa A, Grobler L. Interferon after surgery for women with advanced (Stage II-IV) epithelial ovarian cancer. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD009620. DOI: 10.1002/14651858.CD009620.pub2.

Author Information

  1. Stellenbosch University, Centre for Evidence-based Health Care, Faculty of Medicine and Health Sciences, Cape Town, Western Cape, South Africa

*Aramide O Lawal, Centre for Evidence-based Health Care, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 19063, Tygerberg, Cape Town, Western Cape, 7505, South Africa. aramide0319@yahoo.com.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 6 JUN 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included trials.
[Figure 3]
Figure 3. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 4]
Figure 4. Forest plot of comparison: 1 Interferon versus observation alone, outcome: 1.1 Overall survival.
[Figure 5]
Figure 5. Forest plot of comparison: 2 Interferon + chemotherapy versus chemotherapy alone, outcome: 2.1 Overall survival.
[Figure 6]
Figure 6. Forest plot of comparison: 2 Interferon + chemotherapy versus chemotherapy alone, outcome: 2.2 Progression free survival.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Interferon versus observation alone, Outcome 1 Overall survival.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Interferon versus observation alone, Outcome 2 Progression-Free Survival.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Interferon versus observation alone, Outcome 3 Adverse event (flu-like symptoms).
[Analysis 1.4]
Analysis 1.4. Comparison 1 Interferon versus observation alone, Outcome 4 Adverse event (fatigue).
[Analysis 1.5]
Analysis 1.5. Comparison 1 Interferon versus observation alone, Outcome 5 Adverse event (nausea/ vomiting).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Interferon + chemotherapy versus chemotherapy alone, Outcome 1 Overall survival.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Interferon + chemotherapy versus chemotherapy alone, Outcome 2 Progression-Free Survival.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Interferon + chemotherapy versus chemotherapy alone, Outcome 3 Complete clinical response.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Interferon + chemotherapy versus chemotherapy alone, Outcome 4 Adverse event (flu-like symptoms).
[Analysis 2.5]
Analysis 2.5. Comparison 2 Interferon + chemotherapy versus chemotherapy alone, Outcome 5 Adverse event (fatigue).
[Analysis 2.6]
Analysis 2.6. Comparison 2 Interferon + chemotherapy versus chemotherapy alone, Outcome 6 Adverse event (neurotoxicity).
[Analysis 2.7]
Analysis 2.7. Comparison 2 Interferon + chemotherapy versus chemotherapy alone, Outcome 7 Adverse event (alopecia).
[Analysis 2.8]
Analysis 2.8. Comparison 2 Interferon + chemotherapy versus chemotherapy alone, Outcome 8 Adverse event (anaemia).