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Hormone therapy for sexual function in perimenopausal and postmenopausal women

  1. Carolina O Nastri1,2,
  2. Lucia A Lara1,
  3. Rui A Ferriani1,
  4. Ana Carolina JS Rosa-e-Silva1,
  5. Jaqueline BP Figueiredo1,2,
  6. Wellington P Martins1,2,*

Editorial Group: Cochrane Gynaecology and Fertility Group

Published Online: 5 JUN 2013

Assessed as up-to-date: 12 DEC 2012

DOI: 10.1002/14651858.CD009672.pub2


How to Cite

Nastri CO, Lara LA, Ferriani RA, Rosa-e-Silva ACJS, Figueiredo JBP, Martins WP. Hormone therapy for sexual function in perimenopausal and postmenopausal women. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD009672. DOI: 10.1002/14651858.CD009672.pub2.

Author Information

  1. 1

    University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Sao Paulo, Brazil

  2. 2

    Ultrasonography and Retraining Medical School of Ribeirao Preto (EURP), Ribeirao Preto, Sao Paulo, Brazil

*Wellington P Martins, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, University of Sao Paulo, Hospital das Clinicas da FMRP-USP, 8 andar, Campus Universitario da USP, Ribeirao Preto, Sao Paulo, 14048-900, Brazil. wpmartins@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 5 JUN 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Figure 3]
Figure 3. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 4]
Figure 4. Forest plot of comparison: 1 Estrogens alone, outcome: 1.1 Composite score.
[Figure 5]
Figure 5. Forest plot of comparison: 2 Estrogens + Progestogens, outcome: 2.1 Composite score.
[Figure 6]
Figure 6. Forest plot of comparison: 3 Synthetic steroids, outcome: 3.1 Composite score.
[Figure 7]
Figure 7. Forest plot of comparison: 4 SERMs, outcome: 4.1 Composite score.
[Figure 8]
Figure 8. Forest plot of comparison: 5 SERMs + estrogens, outcome: 5.1 Composite score.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Estrogens alone, Outcome 1 Composite score.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Estrogens alone, Outcome 2 Frequency of sexual activity.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Estrogens alone, Outcome 3 Libido, desire or interest in sex.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Estrogens alone, Outcome 4 Arousal.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Estrogens alone, Outcome 5 Fantasy.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Estrogens alone, Outcome 6 Orgasm.
[Analysis 1.7]
Analysis 1.7. Comparison 1 Estrogens alone, Outcome 7 Number of orgasms.
[Analysis 1.8]
Analysis 1.8. Comparison 1 Estrogens alone, Outcome 8 Pleasure or enjoyment of sex.
[Analysis 1.9]
Analysis 1.9. Comparison 1 Estrogens alone, Outcome 9 Satisfaction.
[Analysis 1.10]
Analysis 1.10. Comparison 1 Estrogens alone, Outcome 10 Dyspareunia.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Estrogens + progestogens, Outcome 1 Composite score.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Estrogens + progestogens, Outcome 3 Libido, desire or interest in sex.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Estrogens + progestogens, Outcome 4 Libido, desire or interest in sex.
[Analysis 2.5]
Analysis 2.5. Comparison 2 Estrogens + progestogens, Outcome 5 Arousal.
[Analysis 2.6]
Analysis 2.6. Comparison 2 Estrogens + progestogens, Outcome 6 Fantasy.
[Analysis 2.8]
Analysis 2.8. Comparison 2 Estrogens + progestogens, Outcome 8 Number of orgasms.
[Analysis 2.10]
Analysis 2.10. Comparison 2 Estrogens + progestogens, Outcome 10 Satisfaction.
[Analysis 2.11]
Analysis 2.11. Comparison 2 Estrogens + progestogens, Outcome 11 Satisfaction.
[Analysis 2.12]
Analysis 2.12. Comparison 2 Estrogens + progestogens, Outcome 12 Dyspareunia.
[Analysis 2.13]
Analysis 2.13. Comparison 2 Estrogens + progestogens, Outcome 13 Dyspareunia.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Synthetic steroids, Outcome 1 Composite score.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Synthetic steroids, Outcome 3 Libido, desire or interest in sex.
[Analysis 3.4]
Analysis 3.4. Comparison 3 Synthetic steroids, Outcome 4 Arousal.
[Analysis 3.7]
Analysis 3.7. Comparison 3 Synthetic steroids, Outcome 7 Number of orgasms.
[Analysis 3.9]
Analysis 3.9. Comparison 3 Synthetic steroids, Outcome 9 Satisfaction.
[Analysis 3.10]
Analysis 3.10. Comparison 3 Synthetic steroids, Outcome 10 Dyspareunia.
[Analysis 4.1]
Analysis 4.1. Comparison 4 SERMs, Outcome 1 Composite score.
[Analysis 4.2]
Analysis 4.2. Comparison 4 SERMs, Outcome 2 Frequency of sexual activity.
[Analysis 4.3]
Analysis 4.3. Comparison 4 SERMs, Outcome 3 Libido, desire or interest in sex.
[Analysis 4.4]
Analysis 4.4. Comparison 4 SERMs, Outcome 4 Arousal.
[Analysis 4.5]
Analysis 4.5. Comparison 4 SERMs, Outcome 5 Arousal.
[Analysis 4.6]
Analysis 4.6. Comparison 4 SERMs, Outcome 6 Fantasy.
[Analysis 4.7]
Analysis 4.7. Comparison 4 SERMs, Outcome 7 Fantasy.
[Analysis 4.8]
Analysis 4.8. Comparison 4 SERMs, Outcome 8 Orgasm.
[Analysis 4.9]
Analysis 4.9. Comparison 4 SERMs, Outcome 9 Number of orgasms.
[Analysis 4.10]
Analysis 4.10. Comparison 4 SERMs, Outcome 10 Pleasure or enjoyment of sex.
[Analysis 4.11]
Analysis 4.11. Comparison 4 SERMs, Outcome 11 Satisfaction.
[Analysis 4.12]
Analysis 4.12. Comparison 4 SERMs, Outcome 12 Dyspareunia.
[Analysis 5.1]
Analysis 5.1. Comparison 5 SERMs + estrogens, Outcome 1 Composite score.
[Analysis 5.4]
Analysis 5.4. Comparison 5 SERMs + estrogens, Outcome 4 Arousal.
[Analysis 5.5]
Analysis 5.5. Comparison 5 SERMs + estrogens, Outcome 5 Fantasy.
[Analysis 5.9]
Analysis 5.9. Comparison 5 SERMs + estrogens, Outcome 9 Satisfaction.