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Transcranial direct current stimulation (tDCS) for improving aphasia in patients after stroke

  1. Bernhard Elsner1,*,
  2. Joachim Kugler1,
  3. Marcus Pohl2,
  4. Jan Mehrholz1,3

Editorial Group: Cochrane Stroke Group

Published Online: 25 JUN 2013

Assessed as up-to-date: 3 MAY 2013

DOI: 10.1002/14651858.CD009760.pub2


How to Cite

Elsner B, Kugler J, Pohl M, Mehrholz J. Transcranial direct current stimulation (tDCS) for improving aphasia in patients after stroke. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD009760. DOI: 10.1002/14651858.CD009760.pub2.

Author Information

  1. 1

    Technical University Dresden, Department of Public Health, Dresden Medical School, Dresden, Sachsen, Germany

  2. 2

    Klinik Bavaria Kreischa, Abteilung Neurologie und Fachübergreifende Rehabilitation, Kreischa, Germany

  3. 3

    Private Europäische Medizinische Akademie der Klinik Bavaria in Kreischa GmbH, Wissenschaftliches Institut, 01731 Kreischa, Germany

*Bernhard Elsner, Department of Public Health, Dresden Medical School, Technical University Dresden, Fetscherstr. 74, Dresden, Sachsen, 01307, Germany. brnhrd.lsnr@googlemail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 25 JUN 2013

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This is not the most recent version of the article. View current version (01 MAY 2015)

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Floel 2011 {published data only}
  • Flöel A, Meinzer M, Kirstein R, Nijhof S, Deppe M, Knecht S, et al. Short-term anomia training and electrical brain stimulation. Stroke 2011;42(7):2065-7.
  • NCT00822068. Improvement of language disturbances after stroke by intensive training and electrical brain stimulation. http://clinicaltrials.gov/show/NCT00822068 (accessed 6 January 2013).
Kang 2011 {published data only}
  • Kang EK, Kim YK, Sohn HM, Cohen LG, Paik N-J. Improved picture naming in aphasia patients treated with cathodal tDCS to inhibit the right Broca's homologue area. Restorative Neurology and Neuroscience 2011;29(3):141-52.
  • Kang EK, Sohn HM, Oh MK, Oh BM Jeon JY, Kim DY, et al. Paradoxical facilitatory effect of cathodal transcranial direct current stimulation on poststroke aphasia. Archives of Physical Medicine and Rehabilitation 2007;88:E8.
Marangolo 2011 {published data only}
  • Marangolo P, Marinelli CV, Bonifazi S, Fiori V, Ceravolo MG, Provinciali L, et al. Electrical stimulation over the left inferior frontal gyrus (IFG) determines long-term effects in the recovery of speech apraxia in three chronic aphasics. Behavioural Brain Research 2011;225(2):498-504.
Monti 2008a {published data only}
  • Cappa SF. Current to the brain improves word-finding difficulties in aphasic patients. Journal of Neurology, Neurosurgery, and Psychiatry 2008;79(4):364.
  • Monti A, Cogiamanian F, Marceglia S, Ferrucci R, Mameli F, Mrakic-Sposta S, et al. Improved naming after transcranial direct current stimulation in aphasia. Journal of Neurology, Neurosurgery, and Psychiatry 2008;79(4):451-3.
You 2011 {published data only}
  • You DS, Kim DY, Chun MH, Jung SE, Park SJ. Cathodal transcranial direct current stimulation of the right Wernicke's area improves comprehension in subacute stroke patients. Brain and Language 2011;119(1):1-5.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Cotelli 2011 {published data only}
  • Cotelli M, Fertonani A, Miozzo A, Rosini S, Manenti R, Padovani A, et al. Anomia training and brain stimulation in chronic aphasia. Neuropsychological Rehabilitation 2011;21(5):717-41.
Fiori 2011 {published data only}
  • Fiori V, Coccia M, Marinelli CV, Vecchi V, Bonifazi S, Ceravolo MG, et al. Transcranial direct current stimulation improves word retrieval in healthy and nonfluent aphasic subjects. Journal of Cognitive Neuroscience 2011;23(9):2309-23.
Fridriksson 2011 {published data only}
Holland 2011 {published data only}
Monti 2008b {published data only}
  • Monti A, Cogiamanian F, Marceglia S, Ferrucci R, Mameli F, Mrakic-Sposta S, et al. Improved naming after transcranial direct current stimulation in aphasia. Journal of Neurology, Neurosurgery, and Psychiatry 2008;79(4):451-3.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Baker 2010 {published data only}
  • Baker JM. Using Transcranial Direct Current Stimulation to Treat Aphasia [Dissertation]. University of South Carolina, 2010.
  • Baker JM, Rorden C, Fridriksson J. Using transcranial direct-current stimulation to treat stroke patients with aphasia. Stroke 2010;6:1229-36.
Vines 2011 {published data only}
  • Vines BW, Norton AC, Schlaug G. Applying transcranial direct current stimulation in combination with melodic intonation therapy facilitates language recovery for Broca's aphasic patients. Stroke 2007;38(2):519.
  • Vines BW, Norton AC, Schlaug G. Non-invasive brain stimulation enhances the effects of melodic intonation therapy. Frontiers in Psychology 2011;2:230.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
JPRN-UMIN000008467 {published data only}
  • JPRN-UMIN000008467. Transcranial direct current stimulation combined with speech therapy among patients with aphasia. http://apps.who.int/trialsearch/Trial.aspx?TrialID=JPRN-UMIN000008467 (accessed 6 January 2013).
NCT00854893 {published data only}
  • NCT00854893. Enhance of language learning with neurostimulation. http://clinicaltrials.gov/show/NCT00854893 (accessed 6 January 2013).
NCT01221779 {published data only}
  • NCT01221779. Chronic Aphasia - improved by intensive training and electrical brain stimulation. http://clinicaltrials.gov/show/NCT01221779 (accessed 6 January 2013).
NCT01486654 {published data only}
  • NCT01486654. Transcranial direct current stimulation and aphasia language therapy. http://clinicaltrials.gov/show/NCT01486654 (accessed 6 January 2013).
NCT01651884 {published data only}
  • NCT01651884. Effects of tDCS versus HD-tDCS for stroke rehabilitation. http://clinicaltrials.gov/show/NCT01651884 (accessed 6 January 2013).
NCT01686373 {published data only}
  • NCT01686373. Brain stimulation and aphasia treatment. http://clinicaltrials.gov/show/NCT01686373 (accessed 6 January 2013).
NCT01701713 {published data only}
  • NCT01701713. TDCS in acute stroke. http://clinicaltrials.gov/show/NCT01701713 (accessed 6 January 2013).
NCT01709383 {published data only}
  • NCT01709383. Using transcranial direct current stimulation (tDCS) to improve post-stroke aphasia. http://clinicaltrials.gov/show/NCT01709383 (accessed 6 January 2013).

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
Benson 1996
  • Benson DF, Ardila A. Aphasia: A Clinical Perspective. New York: Oxford University Press, 1996.
Bhogal 2003
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Brady 2012
Cherney 2008
  • Cherney LR, Patterson JP, Raymer A, Frymark T, Schooling T. Evidence-based systematic review: effects of intensity of treatment and constraint-induced language therapy for individuals with stroke-induced aphasia. Journal of Speech, Language, and Hearing Research 2008;51(5):1282-99.
Cruice 2003
  • Cruice M, Worrall L, Hickson L, Murison R. Finding a focus for quality of life with aphasia: social and emotional health, and psychological well-being. Aphasiology 2003;17(4):333-53.
Dalemans 2010
  • Dalemans RJ, De Witte LP, Beurskens AJ, Van Den Heuvel WJ, Wade DT. An investigation into the social participation of stroke survivors with aphasia. Disability and Rehabilitation 2010;32(20):1678-85.
De Vries 2010
  • De Vries MH, Barth AC, Maiworm S, Knecht S, Zwitserlood P, Flöel A. Electrical stimulation of Broca's area enhances implicit learning of an artificial grammar. Journal of Cognitive Neuroscience 2010;22(11):2427-36.
Dickey 2010
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Hesse 2011
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