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Vitamin D supplementation for preventing recurrent stroke and vascular events in patients with stroke or transient ischaemic attack

  • Protocol
  • Intervention

Authors

  • Ayeesha K Kamal,

    Corresponding author
    1. Aga Khan University Hospital, Stroke Service, International Cerebrovascular Translational Clinical Research Training Program, Section of Neurology, Department of Medicine, Karachi, Pakistan
    • Ayeesha K Kamal, Stroke Service, International Cerebrovascular Translational Clinical Research Training Program, Section of Neurology, Department of Medicine, Aga Khan University Hospital, Stadium Road, PO Box 3500, Karachi, 74800, Pakistan. ayeesha.kamal@aku.edu.

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  • Farzin Majeed,

    1. Aga Khan University Hospital, Stroke Service, International Cerebrovascular Translational Clinical Research Training Program, Section of Neurology, Department of Medicine, Karachi, Pakistan
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  • Imama Naqvi

    1. Aga Khan University Hospital, Stroke Service, International Cerebrovascular Translational Clinical Research Training Program, Section of Neurology, Department of Medicine, Karachi, Pakistan
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective

To study the effect of vitamin D supplementation alone or in combination with calcium, for preventing recurrent stroke (fatal or non-fatal) among patients with a prior history of stroke or TIA.

Secondary objective

To assess the effect of vitamin D supplementation with or without calcium for the prevention of composite vascular events (stroke, MI, PAD and death from vascular cause) and all-cause mortality, in patients with a prior history of stroke or TIA.