Propofol infusion for paediatric sedation

  • Protocol
  • Intervention



This is the protocol for a review and there is no abstract. The objectives are as follows:

  1. To identify the propofol dose and duration of infusion associated with the primary outcome (PRIS and cardiac arrest)

  2. To describe the patient characteristics associated with the primary outcome

  3. To identify a possible association between serious adverse events related to propofol use and the patient care setting (paediatric intensive care, operating room, paediatric emergency or other)

  4. To describe the length of time from initiation and ending of propofol infusion to the development of the primary outcome

  5. To identify the mode of surveillance for AE in different study designs (active surveillance, passive or specific monitoring procedures for collecting AE) and the relationship with identified AE