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Therapeutic and prophylactic drug interventions for Schistosomiasis japonicum

  • Protocol
  • Intervention

Authors

  • Marissa M Alejandria,

    Corresponding author
    1. Department of Medicine, Philippine General Hospital, University of the Philippines, Department of Clinical Epidemiology and Section of Infectious Diseases, Manila, Philippines
    • Marissa M Alejandria, Department of Clinical Epidemiology and Section of Infectious Diseases, Department of Medicine, Philippine General Hospital, University of the Philippines, Manila, 1000, Philippines. issa.alejandria@gmail.com.

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  • Arthur Dessi Roman,

    1. University of the Philippines, Philippines Gneral Hospital, Section of Infectious Diseases, Department of Medicine, Manilla, Philippines
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  • Maria Liza M Gonzales,

    1. College of Medicine-Philippine General Hospital, University of the Philippines, Department of Pediatrics, Manila, National Capital Region, Philippines
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  • Maria Lourdes Amarillo,

    1. University of the Philippines, College of Medicine, Department of Clinical Epidemiology, Manila, Philippines
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  • Vicente Y Belizario,

    1. University of the Philippines, College of Public Health, Manila, Philippines
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  • Qin Liu

    1. School of Public Health & Management, Chongqing Medical University, China Effective Health Care Network, Chongqing, China
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

  1. To assess the effects of different dosing regimens of praziquantel in terms of clinical cure, parasitological cure, and parasite egg reduction.

  2. To assess the effects of artemisinin derivatives compared to praziquantel alone or in combination, in terms of clinical cure, parasitological cure, and parasite egg reduction.

  3. To assess the effects of praziquantel and artemisinin derivatives, alone or in combination, in preventing S. japonicum infections among at risk population groups.