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Fortification of staple foods with vitamin A for preventing vitamin A deficiency

  1. Ingvil Saeterdal1,
  2. Jose O Mora2,
  3. Luz Maria De-Regil3,*

Editorial Group: Cochrane Public Health Group

Published Online: 12 SEP 2012

DOI: 10.1002/14651858.CD010068

How to Cite

Saeterdal I, Mora JO, De-Regil LM. Fortification of staple foods with vitamin A for preventing vitamin A deficiency (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 9. Art. No.: CD010068. DOI: 10.1002/14651858.CD010068.

Author Information

  1. 1

    Norwegian Knowledge Centre for the Health Services, Oslo, Norway

  2. 2

    Independent consultant, Rockville, Maryland, USA

  3. 3

    World Health Organization, Evidence and Programme Guidance, Department of Nutrition for Health and Development, Geneva, Switzerland

*Luz Maria De-Regil, Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, 20 Avenue Appia, Geneva, 1211, Switzerland. deregillu@who.int.

Publication History

  1. Publication Status: New
  2. Published Online: 12 SEP 2012

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References

Additional references

Arroyave 1979
  • Arroyave G. Evaluation of sugar fortification with vitamin A at the national level. Washington, DC: Pan American Health Organization, 1979.
Arroyave 1981
  • Arroyave G, Mejia LA, Aguilar JR. The effect of vitamin A fortification of sugar on the serum vitamin A levels of preschool Guatemalan children: a longitudinal evaluation. American Journal of Clinical Nutrition 1981;34(1):41-9.
Ashong 2012
  • Ashong J, Muthayya S, De-Regil LM, Laillou A, Guyondet C, Moench-Pfanner R, et al. Fortification of rice with vitamins and minerals for addressing micronutrient malnutrition. Cochrane Database of Systematic Reviews 2012, Issue 6. [DOI: 10.1002/14651858.CD009902]
Balshem 2010
  • Balshem H, Helfand M, Schünemann HJ, Oxman AD, Kunz R, Brozek J, et al. GRADE guidelines: rating the quality of evidence. Journal of Clinical Epidemiology 2011;64(4):401-6.
Bauernfeind 1980
  • Bauernfeind JC. The safe use of vitamin A. Washington, DC,: International Vitamin A Consultative Group, 1980.
Beaton 1993
  • Beaton GH, Martorell R, Aronson KJ, Edmonston B, McCabe G, Ross AC, et al. Effectiveness of vitamin A supplementation in the control of young child morbidity and mortality in developing countries; Nutrition Policy Discussion Paper No.13. Geneva: United Nations, Administrative Committee on Coordination/Subcommittee on Nutrition (ACC/SCN), 1993 (http://www.unscn.org/layout/modules/resources/files/Policy_paper_No_13.pdf; accessed 26 July 2012).
Bello 2011
Bessa 2001
  • Bessa EM. Sugar fortification in Zambia. Food and Nutrition Bulletin 2001;22(4):419-22.
Borenstein 2008
  • Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. Introduction to Meta-Analysis (Statistics in Practice). Chichester (UK): John Wiley & Sons, 2008.
Chavasit 1998
  • Chavasit B, Tontisirin K. Triple fortification: instant noodles in Thailand. Food Fortification to end micronutrient malnutrition. State of the Art. Ottawa: The Micronutrient Initiative, 1998:72-6.
Cochrane PHG 2010
  • Cochrane Public Health Group. Guide for developing a Cochrane Protocol. Vol. Version 2, The Cochrane Collaboration. Public Health Group, 2010.
CODEX 1981a
  • CODEX alimentarius. CODEX for edible fats and oils not covered by individual standards (CODEX STAN 19-1981 (Rev. 2-1999)). http://www.codexalimentarius.org/ (accessed 26 July 2012).
CODEX 1981b
  • CODEX alimentarius. CODEX standards for olive oils and olive pomace oils (CODEX STAN 33-198). http://www.codexalimentarius.org/ (accessed 26 July 2012).
CODEX 1985a
  • CODEX alimentarius. CODEX standard for wheat flour (CODEX STAN 152-1985). http://www.codexalimentarius.org/ (accessed 26 July 2012).
CODEX 1985b
  • CODEX alimentarius. CODEX standard for whole maize (corn) meal (CODEX STAN 154-1985). http://www.codexalimentarius.org/ (accessed 26 July 2012).
CODEX 1985c
  • CODEX alimentarius. CODEX standard for degermed maize (corn) meal and maize (corn) grits (CODEX STAN 155-1985). http://www.codexalimentarius.org/ (accessed 26 July 2012).
CODEX 1999a
  • CODEX alimentarius. CODEX standard for named vegetable oils (CODEX STAN 210-1999). http://www.codexalimentarius.org/ (accessed 26 July 2012).
CODEX 1999b
  • CODEX alimentarius. CODEX standard for sugars (CODEX STAN 212-1999). http://www.codexalimentarius.org/ (accessed 26 July 2012).
CODEX 1999c
  • CODEX alimentarius. CODEX standard for general standards for the use of dairy terms (CODEX STAN 206 -1999). http://www.codexalimentarius.org/ (accessed 26 July 2012).
CODEX 2006
  • Codex Alimentarius. Codex General Standard for Food Additives (Codex STAN 192-1995). http://www.codexalimentarius.org/ (accessed 26 July 2012).
Darlow 2011
Dary 2002
  • Dary O, Mora JO, International Vitamin A Consultative Group. Food fortification to reduce vitamin A deficiency: International Vitamin A Consultative Group recommendations. Journal of Nutrition 2002;132(9 Suppl):2927S-33S.
De-Regil 2011
  • De-Regil LM, Suchdev PS, Vist GE, Walleser S, Peña-Rosas JP. Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age. Cochrane Database of Systematic Reviews 2011, Issue 9. [DOI: 10.1002/14651858.CD008959.pub2]
De-Regil 2012
  • De-Regil LM, Jefferds MED, Peña-Rosas JP. Point-of-use fortification of foods with micronutrient powders containing iron in children of preschool and school age. Cochrane Database of Systematic Reviews 2012, Issue 2. [DOI: 10.1002/14651858.CD009666]
EPOC 2010
  • EPOC. EPOC data collection checklist, chapter 6. www.epoc.cochrane.org/sites/epoc.cochrane.org/files/uploads/Risk%20of%20Bias%2005-01-2009.doc 2010 (accessed 26 July 2012).
Evans 2003
  • Evans T,  Brown H. Road traffic crashes: operationalising equity in the context of health sector reform. Injury Control and Safety Promotion 2003;10:11-12.
Fawzi 1993
Gogia 2011
GRADEpro 2008
  • Jan Brozek, Andrew Oxman, Holger Schünemann. GRADEpro Version 3.2 for Windows. Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group, 2008.
Haider 2011
Higgins 2011
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Horvath 2009
Imdad 2010
  • Imdad A, Herzer K, Mayo-Wilson E, Yakoob MY, Bhutta ZA. Vitamin A supplementation for preventing morbidity and mortality in children from 6 months to 5 years of age. Cochrane Database of Systematic Reviews 2010;12:CD008524.
Mills 2007
  • Mills J, Terasawa E, Tanumihardjo S. Ingestion of excessive preformed vitamin A by mothers amplifies storage of retinyl esters in early fetal livers of captive old world monkeys. American Association for Laboratory Animal Science 2007;57:458–64.
Mora 2005
  • Mora JO, Navas GE, Bonilla J, Sandino I. Virtual control of vitamin A deficiency in Nicaragua. In: Freiere W editor(s). Nutrition in an Active Life. From Knowledge to Action. Washington DC: Pan American Health Organization, Scientific and Technical Publication No. 612, 2005:61-92.
Muhilal 1988
  • Muhilal, Permeisih D, Idjradinata YR, Muherdiyantiningsih, Karyadi D. Vitamin A-fortified monosodium glutamate and health, growth, and survival of children: a controlled field trial. American Journal of Clinical Nutrition 1988;48(5):1271-6.
Nalubola 1999
NIH 2001
  • Institute of Medicine, Food, Nutrition Board. Vitamin A. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2001:82–146.
Oliveira-Menegozzo 2010
Quadro 2005
  • Quadro L, Hamberger L, Gottesman ME, Wang F, Colantuoni V, Blaner WS, et al. Pathways of vitamin A delivery to the embryo: insights from a new tunable model of embryonic vitamin A deficiency. Endocrinology 2005;146(10):4479–90.
Ramsay 2003
  • Ramsay CR, Matowe L, Grilli R, Grimshaw JM, Thomas RE. Interrupted time series designs in health technology assessment: lessons from two systematic reviews of behavior change strategies. International Journal of Technology Assessment in Health Care 2003;19(4):613-23.
RevMan 2011
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.1. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2011.
Ross 2012
  • Ross AC. Metabolism of vitamin A in early life. Report: WHO technical consultation on vitamin A in newborn health: mechanistic studies. Geneva: World Health Organization, 2012:47-76.
Solon 1996
  • Solon FS, Solon MS, Mehansho H, West KP Jr, Sarol J, Perfecto C, et al. Evaluation of the effect of vitamin A-fortified margarine on the vitamin A status of preschool Filipino children. European Journal of Clinical Nutrition 1996;50(11):720-3.
Sommer 1996
  • Sommer A, West KP Jr. Vitamin A Deficiency: Health, survival, and vision. New York: Oxford University Press, 1996.
van den Broek 2010
  • van den Broek N, Dou L, Othman M, Neilson JP, Gates S, Gülmezoglu AM. Vitamin A supplementation during pregnancy for maternal and newborn outcomes. Cochrane Database of Systematic Reviews 2010, Issue 11. [DOI: 10.1002/14651858.CD008666.pub2]
West 1991
  • West KP. Dietary vitamin A deficiency: effects on growth, infection and mortality. Food and Nutrition Bulletin 1991;13(2):77.
WHO 2009a
  • World Health Organization (WHO). Global Prevalence of Vitamin A Deficiency in Populations at Risk 1993-2005. Global Database on Vitamin A Deficiency. Geneva: World Health Organization, 2009.
WHO 2009b
  • World Health Organization (WHO). Global Health Risks: mortality and burden of disease attributable to selected major risks. Geneva: World Health Organization, 2009.
WHO 2011a
  • World Health Organization (WHO). Serum Retinol Concentrations for Determining the Prevalence of Vitamin A Deficiency in Populations. Geneva: World Health Organization, 2011.
WHO 2011b
  • World Health Organization (WHO). Guideline: Vitamin A Supplementation for Infants and Children 6-59 Months of Age. Geneva: World Health Organization, 2011.
WHO/FAO 2004
  • World Health Organization/Food and Agriculture Organization (WHO/FAO). Vitamin and Mineral Requirements in Human Nutrition. Geneva: World Health Organization, 2004.
WHO/FAO 2006
  • World Health Organization/Food and Agriculture Organization (WHO/FAO). Guidlines on Food Fortification with Micronutrients. Geneva: World Health Organization and Food and Agriculture Organization of the United Nations, 2006.
Wiysonge 2011
Wu 2005
Zlotkin 2005