Intervention Protocol

Adjunctive antioxidants for bipolar disorder

  1. Pedro V S Magalhães1,*,
  2. Olivia Dean2,
  3. Ana Cristina Andreazza3,
  4. Michael Berk4,
  5. Flávio Kapczinski5

Editorial Group: Cochrane Depression, Anxiety and Neurosis Group

Published Online: 17 OCT 2012

DOI: 10.1002/14651858.CD010142

How to Cite

Magalhães PVS, Dean O, Andreazza AC, Berk M, Kapczinski F. Adjunctive antioxidants for bipolar disorder (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 10. Art. No.: CD010142. DOI: 10.1002/14651858.CD010142.

Author Information

  1. 1

    National Institute for Translational Medicine, Laboratório de Psiquiatria Molecular, Porto Alegre, RS, Brazil

  2. 2

    The University of Melbourne, Mental Health Research Institute, Swanston Centre, Geelong, Victoria, Australia

  3. 3

    University of British Columbia, Department of Psychiatry, Canada, Canada

  4. 4

    The University of Melbourne, Department of Clinical and Biomedical Sciences: Barwon Heath, Geelong, Victoria, Australia

  5. 5

    Hospital de Clínicas de Porto Alegre, Department of Psychiatry/INCT Translational Medicine, Porto Alegre, RS, Brazil

*Pedro V S Magalhães, Laboratório de Psiquiatria Molecular, National Institute for Translational Medicine, Rua Ramiro Barcelos, 2350 - CEP 90035-903, Porto Alegre, RS, 90035-903, Brazil.

Publication History

  1. Publication Status: New
  2. Published Online: 17 OCT 2012




  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To assess the effects of specific drugs with antioxidant properties, in comparison with placebo, as adjunctive treatment to standard mood-stabilising treatment for improving acute mood episodes and preventing relapse in people with bipolar disorder.

Given the diverse range of antioxidant drugs under consideration we will only seek to draw conclusions regarding the efficacy of individual drugs as an adjunct to mood stabilisers and there will be no comment on relative efficacy between different antioxidants.