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Adjunctive antioxidants for bipolar disorder

  • Protocol
  • Intervention

Authors

  • Pedro V S Magalhães,

    Corresponding author
    1. National Institute for Translational Medicine, Laboratório de Psiquiatria Molecular, Porto Alegre, RS, Brazil
    • Pedro V S Magalhães, Laboratório de Psiquiatria Molecular, National Institute for Translational Medicine, Rua Ramiro Barcelos, 2350 - CEP 90035-903, Porto Alegre, RS, 90035-903, Brazil. pedromaga2@gmail.com.

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  • Olivia Dean,

    1. The University of Melbourne, Mental Health Research Institute, Swanston Centre, Geelong, Victoria, Australia
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  • Ana Cristina Andreazza,

    1. University of British Columbia, Department of Psychiatry, Canada, Canada
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  • Michael Berk,

    1. The University of Melbourne, Department of Clinical and Biomedical Sciences: Barwon Heath, Geelong, Victoria, Australia
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  • Flávio Kapczinski

    1. Hospital de Clínicas de Porto Alegre, Department of Psychiatry/INCT Translational Medicine, Porto Alegre, RS, Brazil
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To assess the effects of specific drugs with antioxidant properties, in comparison with placebo, as adjunctive treatment to standard mood-stabilising treatment for improving acute mood episodes and preventing relapse in people with bipolar disorder.

Given the diverse range of antioxidant drugs under consideration we will only seek to draw conclusions regarding the efficacy of individual drugs as an adjunct to mood stabilisers and there will be no comment on relative efficacy between different antioxidants.