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Regular (ICSI) versus ultra-high magnification (IMSI) sperm selection for assisted reproduction

  1. Danielle M Teixeira1,
  2. Mariana AP Barbosa1,
  3. Rui A Ferriani1,
  4. Paula A Navarro1,
  5. Nick Raine-Fenning2,
  6. Carolina O Nastri1,
  7. Wellington P Martins1,*

Editorial Group: Cochrane Gynaecology and Fertility Group

Published Online: 25 JUL 2013

Assessed as up-to-date: 8 MAY 2013

DOI: 10.1002/14651858.CD010167.pub2


How to Cite

Teixeira DM, Barbosa MAP, Ferriani RA, Navarro PA, Raine-Fenning N, Nastri CO, Martins WP. Regular (ICSI) versus ultra-high magnification (IMSI) sperm selection for assisted reproduction. Cochrane Database of Systematic Reviews 2013, Issue 7. Art. No.: CD010167. DOI: 10.1002/14651858.CD010167.pub2.

Author Information

  1. 1

    University of Sao Paulo, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, Ribeirao Preto, Sao Paulo, Brazil

  2. 2

    University of Nottingham, Division of Obstetrics and Gynaecology, School of Clinical Sciences, Nottingham, UK

*Wellington P Martins, Department of Obstetrics and Gynecology, Medical School of Ribeirao Preto, University of Sao Paulo, Hospital das Clínicas da FMRP-USP, 8 andar, Campus Universitário, Campus Universitario da USP, Ribeirao Preto, Sao Paulo, 14048-900, Brazil. wpmartins@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 25 JUL 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Figure 3]
Figure 3. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 4]
Figure 4. Forest plot of comparison: 1 Ultra high (IMSI) versus regular magnification (ICSI), outcome: 1.1 Live birth per allocated couple.
[Figure 5]
Figure 5. Forest plot of comparison: 1 Ultra high (IMSI) versus regular magnification (ICSI), outcome: 1.2 Clinical pregnancy per allocated couple.
[Figure 6]
Figure 6. Funnel plot of comparison: 1 Ultra high (IMSI) versus regular magnification (ICSI), outcome: 1.2 Clinical pregnancy per allocated couple.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Ultra high (IMSI) versus regular magnification (ICSI), Outcome 1 Live birth per allocated couple.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Ultra high (IMSI) versus regular magnification (ICSI), Outcome 2 Clinical pregnancy per allocated couple.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Ultra high (IMSI) versus regular magnification (ICSI), Outcome 3 Miscarriage per clinical pregnancy.
[Analysis 2.1]
Analysis 2.1. Comparison 2 IMSI versus ICSI: subgroup analysis by sperm quality, Outcome 1 Clinical pregnancy.