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Alginate dressings for venous leg ulcers

  1. Susan O'Meara*,
  2. Marrissa Martyn-St James

Editorial Group: Cochrane Wounds Group

Published Online: 30 APR 2013

Assessed as up-to-date: 30 NOV 2012

DOI: 10.1002/14651858.CD010182.pub2

How to Cite

O'Meara S, Martyn-St James M. Alginate dressings for venous leg ulcers. Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD010182. DOI: 10.1002/14651858.CD010182.pub2.

Author Information

  1. University of York, Department of Health Sciences, York, UK

*Susan O'Meara, Department of Health Sciences, University of York, Area 2 Seebohm Rowntree Building, Heslington, York, YO10 5DD, UK. susan.omeara@york.ac.uk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 30 APR 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Armstrong 1997 {published data only}
  • Armstrong SH, Brown DA, Hill E, Ruckley CV, Pucheault M, Hofman D. A randomized comparative clinical trial of a new hydrofibre dressing versus an alginate dressing in the treatment of exuding leg ulcers. Proceedings of the 5th European Conference on Advances in Wound Management; 1995, 21-24 November; Harrogate, UK. 1995.
  • Armstrong SH, Ruckley CV. Use of a fibrous dressing in exuding leg ulcers. Journal of Wound Care 1997;6(7):322-4.
Harding 2001 {published data only}
  • Harding KG, Price P,  Robinson B, Thomas S, Hofman D. Cost and dressing evaluation of hydrofiber and alginate dressings in the management of community-based patients with chronic leg ulceration. Wounds: A Compendium of Clinical Research & Practice 2001;13(6):229-36.
  • Robinson B, Harding K, Thomas S, Cherry G. Does the dressing make a difference? A comparative cost-effectiveness clinical trial of two modern primary dressings on leg ulcers. European Wound Management Association Conference; 1997, 27-29 April; Milan, Italy. 1997.
  • Robinson BJ. An open, prospective, randomized multi-centre study of a new hydrofibre dressing, Aquacel, in comparison with an alginate in the management of leg ulcers in the UK community. Proceedings of the 6th European Conference on Advances in Wound Management; 1-4 October, 1996; Amsterdam. 1997.
Límová 2003 {published data only}
  • Límová M. Evaluation of two calcium alginate dressings in the management of venous ulcers. Ostomy/Wound Management 2003;49(9):26-8, 30, 32-3.
Moffatt 1992 {published data only}
  • Moffatt CJ, Oldroyd MI, Franks PJ. Assessing a calcium alginate dressing for venous ulcers of the leg. Journal of Wound Care 1992;1(4):22-4.
Smith 1994 {published data only}
  • Smith BA. The dressing makes the difference. Trial of two modern dressings on venous ulcers. Professional Nurse 1994;9(5):348, 350-2.
  • Smith BA. Venous ulcers - a well-healed dresser. 2nd European Conference on Advances in Wound Management; 1992, 20-23 October; Harrogate, UK. 1993.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Anonoymous 1997 {published data only}
  • Anonymous. Differential therapy of chronic wounds [Ein neuer weg zur therapie von dermatomykosen]. Hautarzt 1997;48(2 Suppl):1-4.
Barnett 1987 {published data only}
Bull 1996 {published data only}
  • Bull RH, Andersen KE, Larsen AM, Leigh IM. A comparative study on two alginate dressings: Kaltostat and Comfeel: alginate dressing for exudating venous leg ulcers. Proceedings of the 5th European Conference on Advances in Wound Management; 1995, 21-24 November; Harrogate, UK. 1996.
  • Bull RH, Leigh IM. Alginate dressings for exudating leg ulcers: a randomized study of Comfeel: alginate dressing vs Kaltostat. 5th Annual Meeting of the European Tissue Repair Society; 1995, August 30-September 2; Padova, Italy. 1995.
  • Larsen AM, Ulrik D, Madsen SM. Randomised study on Comfeel: alginate dressing vs Kaltostat on exudating venous leg ulcers. 5th Annual Meeting of the European Tissue Repair Society; 1995, August 30-September 2; Padova, Italy. 1995.
Capillas Pérez 2000 {published data only}
  • Capillas Pérez R, Cabré Aguilar V, Gil Colomé AM, Gaitano García A, Torra i Bou JE. Comparison of the effectiveness and cost of treatment with humid environment as compared to traditional cure. Clinical trial on primary care patients with venous leg ulcers and pressure ulcers [Comparación de la efectividad y coste de la cura en ambiente húmedo frente a la cura tradicional]. Revista de enfermería 2000;23(1):17-24.
Chaloner 1992 {published data only}
  • Chaloner D, Fletcher, Milward P. Clinical trials: comparing dressings. Nursing Standard Special Supplement 1992;7(7):9-11.
de la Brassinne 2006 {published data only}
Dmochowska 1999 {published data only}
  • Dmochowska M, Prokop J, Bielecka S, Urasinska K, Krolicki A, Nagaj E, et al. A randomized, controlled, parallel group clinical trial of a polyurethane foam dressing versus a calcium alginate dressing in the treatment of moderately to heavily exuding venous leg ulcers. Wounds: A Compendium of Clinical Research and Practice 1999;11(1):21-8.
  • Jasiel E, Nowak A, Gwiezdzinski Z, Bowszyc J, Szarmach H, Blaszsyc. A randomized, controlled, parallel-group clinical trial of a new polyurethane foam dressing (Lyofoam Extra) versus a calcium alginate dressing (Sorbsan) plus a low-adherence dressing (Melolin) in the treatment of moderate to heavily exuding venous leg ulcers. Proceedings of the 6th European Conference on Advances in Wound Management; 1-4 October, 1996; Amsterdam. 1996.
  • Nowak A, Bowszyc P, Blaszczyk M. A randomised, controlled, parallel group clinical trial of a new polyurethane foam dressings versus calcium alginate dressing in the treatment of moderately to heavily exuding venous ulcers. Proceedings of the 5th European Conference on Advances in Wound Management; 1995, 21-24 November; Harrogate, UK. 1996.
Kammerlander 2000 {published data only}
  • Kammerlander G, Andriessen A. An alginate dressing vs a hydrofibre dressing in the management of various wound types, a randomized controlled clinical trial. 1st World Healing Congress, Incorporating the 3rd Australian Wound Management Association Conference; 2000, September 10-13; Melbourne, Australia. 2000.
  • Kammerlander G, Andriessen A. An alginate dressing vs. a hydrofiber dressing in the management of various wound types: a randomized controlled clinical trial. 13th Annual Symposium on Advanced Wound Care and 10th Annual Medical Research Forum on Wound Repair; 2000, April 1-4, Dallas, USA. 2000.
Kordestani 2008 {published data only}
  • Kordestani S, Shahrezaee M, Tahmasebi MN, Hajimahmodi H, Haji Ghasemali D, Abyaneh MS. A randomised controlled trial on the effectiveness of an advanced wound dressing used in Iran. Journal of Wound Care 2008;17(7):323-7.
Límová 2002 {published data only}
  • Limova M. Evaluation of a new hydrocolloid dressing in the management of venous stasis ulcers. 5th European Conference on Advances in Wound Management; 1995, 21-24 November; Harrogate, UK. 1995.
  • Límová M, Troyer-Caudle J. Controlled, randomized clinical trial of 2 hydrocolloid dressings in the management of venous insufficiency ulcers. Journal of Vascular Nursing 2002;20(1):22-32.
Moody 1991 {published data only}
  • Moody M. Tissue viability. Calcium alginate: a dressing trial. Nursing Standard - Special Supplement 1991;4(13):3-6.
Mulder 1995 {published data only}
  • Mulder G, Jensen J, Seeley J. Use of a hydrocellular dressing versus a calcium alginate in the treatment of venous leg ulcers. 5th Annual Meeting of the European Tissue Repair Society; 1995, August 30-September 2; Padova, Italy. 1995.
  • Mulder GD, Como A, Seeley J, Peak Andrews K. A randomised clinical study to evaluate and compare the performance of Allevyn hydrocellular dressing and Kaltostat alginate dressing in the treatment of venous ulcers. Proceedings of the 4th European Conference on Advances in Wound Management; 1994, September 6-9; Copenhagen, Denmark. 1995.
Petres 1994 {published data only}
  • Petres J, Rompel R, Nölting S, Payne J. Alginates versus hydrocolloids in the treatment of venous leg ulcers. 3rd European Conference on Advances in Wound Management; 1993, 19-22 October; Harrogate, UK. 1994.
Romanelli 2008 {published data only}
  • Romanelli M, Ellervee T, Jarve H, Kaha E. Amelogenins (Xelma) in hard-to-heal venous leg ulcers, an open regime investigation. 16th Conference of the European Wound Management Association; 2006, 18-20 May; Prague, Czech Republic. 2006.
  • Romanelli M, Kaha E, Stege H, Wnorowski JW, Vowden P, Majamaa H, et al. Effect of amelogenin extracellular matrix protein and compression on hard-to-heal venous leg ulcers: follow-up data. Journal of Wound Care 2008;17(1):17-8, 20-3.
  • Vowden P, Romanelli M, Peter R, Bostrom A, Josefsson A, Stege H. The effect of amelogenins (Xelma) on hard-to-heal venous leg ulcers. Wound Repair and Regeneration 2006;14(3):240-6.
Romero-Cerecero 2012 {published data only}
  • Romero-Cerecero O, Zamilpa- Álvarez A, Jiménez-Ferrer E, Tortoriello J. Exploratory study on the effectiveness of a standardized extract from Ageratina pichinchensis in patients with chronic venous leg ulcers. Planta Medica 2012;78(4):304-10.
Schulze 2001 {published data only}
  • Schulze H-J, Lane C, Charles H, Ballard K, Hampton S, Moll I. Evaluating a superabsorbent hydropolymer dressing for exuding venous leg ulcers. Journal of Wound Care 2001;10(1):511-8.
Scurr 1994 {published data only}
  • Scurr JH, Wilson LA, Coleridge Smith PD. A comparison of the effects of semipermeable foam and film secondary dressings over alginate dressings on the healing and management of venous ulcers. Wounds: A Compendium of Clinical Research and Practice 1993;5(6):259-65.
  • Scurr JH, Wilson LA, Coleridge-Smith PD. A comparison of calcium alginate and hydrocolloid dressings in the management of chronic venous ulcers. Wounds: A Compendium of Clinical Research and Practice 1994;6(1):1-8.
Sibbald 2005 {published data only}
  • Sibbald G, Brassard A, Kay D, Gulliver W, Hull P, Giard F, et al. Evaluation of a new fibronectin based dressing in the treatment of venous leg ulcers. European Wound Management Association Conference; 2005, 15-17 September; Stuttgart, Germany. 2005.
Stacey 1997 {published data only}
  • Stacey MC, Jopp-Mckay AG, Rashid P, Hoskin SE, Thompson PJ. The influence of dressings on venous ulcer healing--a randomised trial. European Journal of Vascular and Endovascular Surgery 1997;13(2):174-9.
Thomas 1989 {published data only}
  • Thomas S. Sorbsan in the management of leg ulcers. Pharmaceutical Journal 1989;243:706-9.
Wild 2010 {published data only}
  • Wild T, Eberlein T, Andriessen A. Wound cleansing efficacy of two cellulose-based dressings. Wounds UK 2010;6(3):14-21.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
3M 2012
  • 3M. 3M™ Tegaderm™ High Integrity and High Gelling Alginate Dressings. Available from http://www.3m.com/product/information/Tegaderm-HI-HG-Alginate-Dressing.html (accessed October 2012) 2012.
Al-Kurdi 2008
Augustin 2012
  • Augustin M, Brocatti LK, Rustenbach SJ, Schäfer I, Herberger K. Cost-of-illness of leg ulcers in the community. International Wound Journal 2012;doi: 10.1111/j.1742-481X.2012.01089.x.:[Epub ahead of print].
Becker 2011
  • Becker LA, Oxman AD. Chapter 22: Overviews of reviews. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
BNF 2012
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Boateng 2008
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Davies 2005
  • Davies CE, Turton G, Woolfrey G, Elley R, Taylor M. Exploring debridement options for chronic venous leg ulcers. British Journal of Nursing 2005;14(7):393-7.
Deeks 2011
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Doughty 2007
  • Doughty DB, Holbrook R. Lower-extremity ulcers of vascular etiology. In: Bryant RA, Nix DP editor(s). Acute and Chronic Wounds: Current Management Concepts. 3rd Edition. St Louis, Missouri, USA: Mosby, 2007.
Flemming 2001
Gohel 2005
  • Gohel MS, Taylor M, Earnshaw JJ, Heather BP, Poskitt KR, Whyman MR. Risk factors for delayed healing and recurrence of chronic venous leg ulcers - an analysis of 1324 legs. European Journal of Vascular and Endovascular Surgery 2005;29(1):74-7.
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Herber 2007
Higgins 2003
Higgins 2011
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Iglesias 2004
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Jeffcoate 2009
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Lefebvre 2011
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Lorimer 2003
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