This is the protocol for a review and there is no abstract. The objectives are as follows:
To assess the effects of prenatal exposure to commonly prescribed AEDs on neurodevelopmental outcomes in the child.
It is intended that this review will examine neurodevelopmental outcomes following exposure to AEDs in pregnancy compared to unexposed pregnancies in women representative of the general population or unexposed pregnancies in women with epilepsy. We also intend to compare the neurodevelopmental outcomes following specific monotherapy AED exposure against each other and where possible against classes of polytherapy combinations (e.g. polytherapy including sodium valproate).