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Tranexamic acid for reducing mortality in emergency and urgent surgery

  1. Pablo Perel1,*,
  2. Katharine Ker1,
  3. Carlos Hernando Morales Uribe2,
  4. Ian Roberts1

Editorial Group: Cochrane Injuries Group

Published Online: 31 JAN 2013

Assessed as up-to-date: 22 AUG 2012

DOI: 10.1002/14651858.CD010245.pub2


How to Cite

Perel P, Ker K, Morales Uribe CH, Roberts I. Tranexamic acid for reducing mortality in emergency and urgent surgery. Cochrane Database of Systematic Reviews 2013, Issue 1. Art. No.: CD010245. DOI: 10.1002/14651858.CD010245.pub2.

Author Information

  1. 1

    London School of Hygiene & Tropical Medicine, Cochrane Injuries Group, London, UK

  2. 2

    Universidad de Antioquia, Department of General Surgery, Medellin, Antioquia, Colombia

*Pablo Perel, Cochrane Injuries Group, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. pablo.perel@Lshtm.ac.uk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 31 JAN 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 3]
Figure 3. Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies. Five studies are included in this review.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Tranexamic acid versus control, Outcome 1 Mortality.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Tranexamic acid versus control, Outcome 2 Transfusion.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Tranexamic acid versus control, Outcome 3 Deep venous thrombosis.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Tranexamic acid versus control, Outcome 4 Pulmonary embolism.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Tranexamic acid versus control, Outcome 5 Myocardial Infarction.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Tranexamic acid versus control, Outcome 6 Stroke.