Topical anaesthesia for needle-related pain in newborn infants

  • Protocol
  • Intervention

Authors


Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Compare the topical anaesthetics amethocaine (Ametop) and EMLA in terms of anaesthetic efficacy and safety in newborn term or preterm infants requiring an invasive procedure involving puncture of skin and other tissues with a needle.

Subgroup analysis

We will compare the effects of each topical anaesthetic in the following subgroups of patients:

  • gestational age at birth (term infants 37 weeks' gestation and above); preterm infants (29 to 36 weeks' gestation); very preterm infants (< 29 weeks' gestation);

  • type of infants (e.g. healthy newborn infants (e.g. those in the normal newborn nursery vs. sick infants in the neonatal intensive care unit (NICU)).