Interventions for the treatment of oral and oropharyngeal cancers: targeted therapy and immunotherapy

  • Protocol
  • Intervention

Authors


Abstract

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

Primary objectives

  • To determine whether molecularly targeted therapies, in addition to surgery and/or chemotherapy and/or radiotherapy for oral cavity or oropharyngeal cancers result in increased overall survival, disease free survival, progression free survival, locoregional control and reduced recurrence.

  • To determine whether immunotherapies, in addition to surgery and/or chemotherapy and/or radiotherapy for oral cavity or oropharyngeal cancers result in increased overall survival, disease free survival, progression free survival, locoregional control and reduced recurrence.

Secondary objectives

  • To determine whether molecularly targeted therapies, in addition to surgery and/or chemotherapy and/or radiotherapy for oral cavity oropharyngeal cancers are associated with increased quality of life, harm, costs and patient satisfaction.

  • To determine whether immunotherapies, in addition to surgery and/or chemotherapy and/or radiotherapy for oral cavity or oropharyngeal cancers are associated with increased quality of life, harm, costs and patient satisfaction.