Diagnostic Test Accuracy Protocol
Intra-operative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses
Editorial Group: Cochrane Gynaecological Cancer Group
Published Online: 28 FEB 2013
Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
How to Cite
Ratnavelu NDG, Patel A, Cross P, Bryant A, Martin-Hirsch PPL, Naik R. Intra-operative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD010360. DOI: 10.1002/14651858.CD010360.
- Publication Status: Edited (no change to conclusions)
- Published Online: 28 FEB 2013
This is the protocol for a review and there is no abstract. The objectives are as follows:
To establish the accuracy and other diagnostic parameters (sensitivity, specificity, positive predictive value and negative predictive value) of intraoperative frozen section analysis in histopatholgical diagnosis of ovarian cancer, in comparison to paraffin section reporting.
To establish if intraoperative frozen section analysis allows the surgeon to accurately identify those cases of early stage ovarian cancer which would benefit from optimal surgical staging, therefore avoiding need for restaging procedure or need for adjuvant chemotherapy
To establish the accuracy of frozen section diagnosis in metastatic tumours, mucinous tumours and large thin-walled tumours, where frozen section may miss areas of malignancy.