Intervention Protocol

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Pharmacological interventions other than botulinum toxin for spasticity after stroke

  1. Cameron Lindsay1,
  2. Anand D Pandyan2,*

Editorial Group: Cochrane Stroke Group

Published Online: 28 FEB 2013

Assessed as up-to-date: 10 NOV 2012

DOI: 10.1002/14651858.CD010362

How to Cite

Lindsay C, Pandyan AD. Pharmacological interventions other than botulinum toxin for spasticity after stroke (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD010362. DOI: 10.1002/14651858.CD010362.

Author Information

  1. 1

    Sandwell and West Birmingham NHS Trust, Department of Physiotherapy, Birmingham, West Midlands, UK

  2. 2

    Keele University, School of Health and Rehabilitation, Keele, UK

*Anand D Pandyan, Professor for Rehabilitation Technology in Health, School of Health and Rehabilitation, Keele University, Keele, ST5 5BG, UK. a.d.pandyan@keele.ac.uk.

Publication History

  1. Publication Status: New
  2. Published Online: 28 FEB 2013

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary

To determine if pharmacological interventions for spasticity are more effective than no intervention, normal practice or control at improving function following stroke.

Secondary

  1. To determine if pharmacological interventions for spasticity after stroke are more effective than no intervention, normal practice or control at:
    1. preventing secondary complications such as pain and contractures;
    2. decreasing spasticity at an impairment level.
  2. To determine if global antispasmodic interventions are more effective than local treatments at improving function after stroke.
  3. To determine if early administration of pharmacological interventions for spasticity (before six months) are more effective than late administration (after six months) of pharmacological intervention at improving function after stroke.
  4. To determine the side effects of the use of pharmacological interventions against placebo.
  5. To determine whether there is a difference between using pharmacological interventions for spasticity compared with no intervention, normal practice or control at improving function of the arm or leg following stroke.

  1. preventing secondary complications such as pain and contractures;
  2. decreasing spasticity at an impairment level.