Diagnostic Test Accuracy Review

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11C-PIB-PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)

  1. Shuo Zhang1,*,
  2. Nadja Smailagic2,
  3. Chris Hyde3,
  4. Anna H Noel-Storr4,
  5. Yemisi Takwoingi5,
  6. Rupert McShane4,
  7. Juan Feng6

Editorial Group: Cochrane Dementia and Cognitive Improvement Group

Published Online: 23 JUL 2014

DOI: 10.1002/14651858.CD010386.pub2


How to Cite

Zhang S, Smailagic N, Hyde C, Noel-Storr AH, Takwoingi Y, McShane R, Feng J. 11C-PIB-PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI). Cochrane Database of Systematic Reviews 2014, Issue 7. Art. No.: CD010386. DOI: 10.1002/14651858.CD010386.pub2.

Author Information

  1. 1

    China Medical University, Department of Neurology, Shengjing Hospital, Shenyang, Liaoning, China

  2. 2

    University of Cambridge, Institute of Public Health, Cambridge, UK

  3. 3

    University of Exeter Medical School, University of Exeter, Institute of Health Research, Exeter, UK

  4. 4

    University of Oxford, Radcliffe Department of Medicine, Oxford, UK

  5. 5

    University of Birmingham, Public Health, Epidemiology and Biostatistics, Birmingham, UK

  6. 6

    Shengjing Hospital, China Medical University, Department of Neurology, Shenyang, China

*Shuo Zhang, Department of Neurology, Shengjing Hospital, China Medical University, 36 Shanhao Street, Shenyang, Liaoning, 110004, China. submission@126.com.

Publication History

  1. Publication Status: New
  2. Published Online: 23 JUL 2014

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Forsberg 2010 {published data only}
  • Forsberg A, Almkvist O, Engler H, Wall A, Langstrom B, Nordberg A. High PIB retention in Alzheimer’s disease in early event with complex relationship with CSF biomarkers and functional parameters. Current Alzheimer Research 2010;7:56-66.
  • Forsberg A, Engler H, Almkvist O, Blomquist G, Hagman G, Wall A, et al. PET imaging of amyloid deposition in patients with mild cognitive impairment. Neurobiology of Aging 2008;29:1456-65.
  • Forsberg A, Engler H, Blomquist G, Almkvist O, Hagman G, Wall A, et al. PET imaging of amyloid depositions in MCI patients using PIB. Journal of Cerebral Blood Flow and Metabolism 2007; Vol. 27 Suppl 1:BO03-01.
  • Nordberg A, Carter SF, Rinne J, Drzezga A, Brooks DJ, Vandenberghe R, et al. A European multicentre PET study of fibrillar amyloid in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging 2013;40(1):104-14.
Grimmer 2013 {published data only}
  • GrimmerT, Wutz C, Drzezga A, Forster S, Forstl H, Ortner M, et al. The usefulness of amyloid imaging in predicting the clinical outcome after two years in subjects with mild cognitive impairment. Current Alzheimer Research 2013;10:82-5.
Jack 2010 {published data only}
  • Beckett 2010. The Alzheimer's Disease Neuroimaging Initiative: Annual change in biomarkers and clinical outcomes. Alzheimer's & Dementia 2010;3:257-64.
  • Burns L, Berman R, Guo Z, Soares H, Kaplita S, Yoo B, et al. The relationship between cerebral spinal fluid (CSF) biomarkers and Pittsburgh compound B (PIB) positron emission tomography (PET) in predicting Alzheimer's disease (AD) [Conference: Alzheimer's Association International Conference, AAIC 11 Paris France. Conference Start: 20110716 Conference End: 20110721. Conference Publication: (var.pagings)]. Alzheimer's & Dementia 2011; Vol. 7, issue 4 Suppl 1:S206.
  • Ewers M, Aisen P, Jagust W, Schuff N, Weiner M, Trojanowski J, et al. CSF biomarker and PIB-PET-derived beta-amyloid signature predicts brain metabolism grey matter and cognitive changes in non-demented subjects [Conference: Alzheimer's Association International Conference, AAIC 11 Paris France. Conference Start: 20110716 Conference End: 20110721. Conference Publication: (var.pagings)]. Alzheimer's & Dementia 2011; Vol. 7, issue 4 Suppl 1:S102.
  • Ishii K, Sakata M, Oda K, Toyohara J, Ishiwata K, Senda M, et al. Age, ApoE e4, and ethnic effect on [C-11] PIB in multinational ADNI studies: Direct comparison of J-ADNI, US-ADNI and AIBL data [Conference: Alzheimer's Association International Conference, AAIC 11 Paris France. Conference Start: 20110716 Conference End: 20110721. Conference Publication: (var.pagings)]. Alzheimer's & Dementia 2011; Vol. 7, issue 4 Suppl 1:S233.
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Koivunen 2011 {published data only}
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  • Koivunen J, Pirttila T, Kemppainen N, Aalto S, Herukka SK, Jauhianen AM, et al. PET amyloid ligand [11C]PIB uptake and cerebrospinal fluid beta-amyloid in mild cognitive impairment. Dementia and Geriatric Cognitive Disorders 2008; Vol. 26, issue 4:378-83.
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Okello 2009 {published data only}
  • Nordberg A, Carter SF, Rinne J, Drzezga A, Brooks DJ, Vandenberghe R, et al. A European multicentre PET study of fibrillar amyloid in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging 2013; Vol. 40, issue 1:104-14.
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Ossenkoppele 2012 {published data only}
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Ossenkoppele 2012a {published data only}
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Villemagne 2011 {published data only}
  • Villain N, Chetelat G, Grassiot B, Bourgeat P, Jones G, Ellis KA, et al. Regional dynamics of amyloid-beta deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: A voxelwise PiB-PET longitudinal study. Brain 2012; Vol. 135, issue 7:2126-39.
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Wolk 2009 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Choo 2011 {published data only}
  • Choo H, Lee DY, Seo EH, Kim YK, Yoon EJ, Lee DS, et al. PIB retention changes in cognitively normal, mild cognitive impairment and Alzheimer's disease: One year follow-up study IL [Conference: Alzheimer's Association International Conference, AAIC 11 Paris France. Conference Start: 20110716 Conference End: 20110721. Conference Publication: (var.pagings)]. Alzheimer's & Dementia 2011; Vol. 7, issue 4 Suppl 1:S208-9.
Driscoll 2011 {published data only}
  • Driscoll I, Zhou Y, An Y, Sojkova J, Davatzikos C, Kraut MA, et al. Lack of association between 11C-PIB longitudinal brain atrophy in non-demented older individuals. Neurobiology of Aging 2011;32:2123-30.
Ellis 2010 {published data only}
  • Ellis KA, Rowe CC, Villemagne VL, Martins RN, Masters CL, Salvado O, et al. addressing population aging and Al;zheimer's disease through the Australian imaging biomarkers and lifestyle study: collaboration with the Alzheimer's Disease Neuroimaging Initiative. Alzheimer's & Dementia 2010;6:291-6.
Fagan 2007 {published data only}
  • Fagan AM, Roe CM, Xiong C, Mintun M, et al. Cerebrospinal fluid tau/beta-amyloid<sub>42</sub> ratio as a prediction of cognitive decline in nondemented older adults. Archives of Neurology 2007; Vol. 64, issue 3:343-9.
Kadir 2012 {published data only}
  • Kadir A, Alkmvist O, Forsberg A, Wall A, Engler H, Langstrom B at al. Dynamic changes in PET amyloid and FDG imaging at diffetrent stages of Alzheimer's disease. Neurobiology of Aging 2012;33:198.e1-198.e14.
Kadir 2012a {published data only}
  • Kadir A, Almkvist O, Forsberg A, Wall A, Engler H, Langstrom B, et al. Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease. Neurobiology of Aging 2012; Vol. 33, issue 1:198.e1-14.
Resnick 2010 {published data only}
Rowe 2010 {published data only}
  • Rowe CC, Ellis KA, Rimajova M, Bourgeat P, Pike KE, Jones G, et al. Amyloid imaging results from the Australian Imaging Biomarkers and Lifestyle (AIBL) study of aging. Neurobiology of Aging 2010;31:1275-83.
Shinotoh 2011 {published data only}
  • Shinotoh H, Shimada H, Hirano S, Tanaka N, Sato K, Kiyoshi F, et al. Longitudinal [11C]PIB PET study in healthy elderly persons, patients with mild cognitive impairment, and Alzheimer's disease [Conference: Alzheimer's Association International Conference, AAIC 11 Paris France. Conference Start: 20110716 Conference End: 20110721. Conference Publication: (var.pagings)]. Alzheimer's & Dementia 2011; Vol. 7, issue 4 Suppl 1:S224.
Sojkova 2008 {published data only}
  • Sojkova J, Beason-Held L, Zhou Y, An Y, Kraut MA, et al. Longitudinal cerebral blood flow and amyloid deposition: An emerging pattern?. Journal of Nuclear Medicine 2008; Vol. 49, issue 9:1465-71.
Sojkova 2011 {published data only}
  • Sojkova J, Zhou Y, An Y, Kraut MA, Ferrucci L, Wong D, et al. Longitudinal patterns of beta-amyloid deposition in nondemented older adults. Archives of Neurology 2011;68(5):644-9.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
DeKosky 2006 {published data only}
  • Dekosky ST, Mathis CA, Price JC, Lopresti BJ, Meltzer CC, Ziolko SK, et al. Human amyloid-imaging studies with Pittsburgh compound-B in mild cognitive impairment (MCI): Is MCI the critical period of amyloid plaque deposition?. Neurology 2006; Vol. 66, issue 5:A60.

Additional references

  1. References to studies included in this review
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  3. References to ongoing studies
  4. Additional references
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