11C-PIB-PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)

  • Protocol
  • Diagnostic



This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows:

To determine the diagnostic accuracy of the PIB-PET index test at various thresholds for detecting participants with mild cognitive impairment at baseline who would clinically convert to Alzheimer’s disease dementia or other forms of dementia at follow-up.

To investigate heterogeneity of test accuracy in the included studies.