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Diagnostic Test Accuracy Protocol

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11C-PIB-PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)

  1. Shuo Zhang1,*,
  2. Nadja Smailagic2,
  3. Chris Hyde3,
  4. Dong Han1,
  5. Anna Noel-Storr4,
  6. Yemisi Takwoingi5,
  7. Rupert McShane4

Editorial Group: Cochrane Dementia and Cognitive Improvement Group

Published Online: 28 FEB 2013

DOI: 10.1002/14651858.CD010386


How to Cite

Zhang S, Smailagic N, Hyde C, Han D, Noel-Storr A, Takwoingi Y, McShane R. 11C-PIB-PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI) (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD010386. DOI: 10.1002/14651858.CD010386.

Author Information

  1. 1

    China Medical University, Department of Neurology, Shengjing Hospital, Shenyang, Liaoning, China

  2. 2

    University of Cambridge, Institute of Public Health, Cambridge, UK

  3. 3

    University of Exeter Medical School, University of Exeter, Peninsula Technology Assessment Group (PenTAG), Exeter, UK

  4. 4

    University of Oxford, Radcliffe Department of Medicine, Oxford, UK

  5. 5

    University of Birmingham, Public Health, Epidemiology and Biostatistics, Birmingham, UK

*Shuo Zhang, Department of Neurology, Shengjing Hospital, China Medical University, 36 Shanhao Street, Shenyang, Liaoning, 110004, China. submission@126.com.

Publication History

  1. Publication Status: New
  2. Published Online: 28 FEB 2013

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Abstract

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  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To determine the diagnostic accuracy of the PIB-PET index test at various thresholds for detecting participants with mild cognitive impairment at baseline who would clinically convert to Alzheimer’s disease dementia or other forms of dementia at follow-up.

To investigate heterogeneity of test accuracy in the included studies.