Diagnostic Test Accuracy Protocol

You have free access to this content

Ultrasonography for diagnosis of acute appendicitis

  1. Jonathan RL Wild1,*,
  2. Nicole Abdul2,
  3. Judith E Ritchie3,
  4. Bo Rud4,
  5. Sally Freels5,
  6. Richard L Nelson6

Editorial Group: Cochrane Colorectal Cancer Group

Published Online: 28 FEB 2013

Assessed as up-to-date: 20 JAN 2013

DOI: 10.1002/14651858.CD010402

How to Cite

Wild JRL, Abdul N, Ritchie JE, Rud B, Freels S, Nelson RL. Ultrasonography for diagnosis of acute appendicitis (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD010402. DOI: 10.1002/14651858.CD010402.

Author Information

  1. 1

    Sheffield Teaching Hospitals NHS Trust, Colorectal Surgery, Sheffield, South Yorkshire, UK

  2. 2

    Northern General Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, South Yorkshire S7 5AU, UK

  3. 3

    University of Sheffield Medical School, Unit of Surgical Oncology, Sheffield, UK

  4. 4

    Bispebjerg Hospital, Department of Surgical Gastroenterology K, Copenhagen NV, Denmark

  5. 5

    University of Illinois School of Public Health, Epidemiology/Biometry, Chicago, Illinois, USA

  6. 6

    Northern General Hospital, Department of General Surgery, Sheffield, Yorkshire, UK

*Jonathan RL Wild, Colorectal Surgery, Sheffield Teaching Hospitals NHS Trust, 35, Whirlow Court Road, Sheffield, South Yorkshire, S11 9NS, UK. jonathanrlwild@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 28 FEB 2013



Additional references

Addiss 1990
Alvarado 1986
Andersen 2005
Andersson 2004
Andersson 2008
  • Andersson M, Andersson RE. The appendicitis inflammatory response score: a tool for the diagnosis of acute appendicitis that outperforms the Alvarado score. World J Surg 2008;32:1843-9.
Basaran 2009
Bickell 2006
Birnbaum 2000
Blomqvist 2001
Bondi 2012
  • Bondi M, Miller R, Zbar A, Hazan Y, Appelman Z, Caspi B, et al. Improving the diagnostic accuracy of ultrasonography in suspected acute appendicitis by the combined transabdominal and transvaginal approach. Am Surg 2012;78:98-103.
Brenner 2007
Case 1998
Chong 2010
  • Chong CF, Adi MI, Thien A, Suyoi A, Mackie AJ, Tin AS, et al. Development of the RIPASA score: a new appendicitis scoring system for the diagnosis of acute appendicitis. Singapore Med J 2010;51:220-5.
Cobben 2009
  • Cobben L, Groot I, Kingma L, Coerkamp E, Puylaert J, Blickman J. A simple MRI protocol in patients with clinically suspected appendicitis: results in 138 patients and effect on outcome of appendectomy. Eur Radiol 2009;19:1175-83.
Cogbill 2011
  • Cogbill TH, Ziegelbein KJ. Computed tomography, magnetic resonance, and ultrasound imaging: basic principles, glossary of terms, and patient safety. Surg Clin North Am 2011;91:1-14.
Doria 2009
  • Doria AS. Optimizing the role of imaging in appendicitis. Pediatr Radiol 2009;39:S144-148.
Enochsson 2004
  • Enochsson L, Gudbjartsson T, Hellberg A, Rudberg C, Wenner J, Ringqvist I, et al. The Fenyo-Lindberg scoring system for appendicitis increases positive predictive value in fertile women--a prospective study in 455 patients randomized to either laparoscopic or open appendectomy. Surg Endosc 2004;18:1509-13.
Feinberg 2011
Gaitan 2011
Gaitini 2008
  • Gaitini D, Beck-Razi N, Mor-Yosef D, Fischer D, Ben Itzhak O, Krausz MM, et al. Diagnosing acute appendicitis in adults: accuracy of color Doppler sonography and MDCT compared with surgery and clinical follow-up. Am J Roentgenol 2008;190:1300-1306.
Golash 2005
Grover 2011
  • Grover CA, Sternbach G. Charles McBurney: McBurney's point. J Emerg Med 2011; Vol. Oct 5. [Epub ahead of print].
Grunewald 1993
  • Grunewald B, Keating J. Should the 'normal' appendix be removed at operation for appendicitis?. J R Coll Surg Edinb 1993;38:158-60.
Hall 2010
  • Hall MJ, DeFrances CJ, Williams SN, Golosinskiy A, Schwartzman A. National Hospital Discharge Survey: 2007 summary. Natl Health Stat Report 2010;24:1-20.
Hangiandreou 2003
Hernanz-Schulman 2010
Hussain 2009
  • Hussain A, Mahmood H, Singhal T, Balakrishnan S, El-Hasani S. What is positive appendicitis? A new answer to an old question. Clinical, macroscopical and microscopical findings in 200 consecutive appendectomies. Singapore Med J 2009;50:1145-9.
Ito 2011
  • Ito K, Ito H, Whang EE, Tavakkolizadeh A. Appendectomy in pregnancy: evaluation of the risks of a negative appendectomy. Am J Surg 2011; Vol. Jul 22. [Epub ahead of print].
Jang 2008
  • Jang SO, Kim BS, Moon DJ. Application of alvarado score in patients with suspected appendicitis. Korean J Gastroenterol 2008;52:27-31.
Keyzer 2005
  • Keyzer C, Zalcman M, De Maertelaer V, Coppens E, Bali MA, Gevenois PA, Van Gansbeke D. Comparison of US and unenhanced multi-detector row CT in patients suspected of having acute appendicitis. Radiology 2005;236: 527-534.
Lameris 2009
Lee 2002
  • Lee JH, Jeong YK, Hwang JC, Ham SY, Yang SO. Graded compression sonography with adjuvant use of a posterior manual compression technique in the sonographic diagnosis of acute appendicitis. Am J Roentgenol 2002;178:863-8.
Lewis 2011
Moberg 1998
Neville 2009
Old 2005
Parks 2011
Patel 2007
  • Patel SJ, Reede DL, Katz DS, Subramaniam R, Amorosa JK. Imaging the pregnant patient for nonobstetric conditions: algorithms and radiation dose considerations. Radiographics 2007;27:1705-22.
Paulson 2005
  • Paulson EK, Harris JP, Jaffe TA, Haugan PA, Nelson RC. Acute appendicitis: added diagnostic value of coronal reformations from isotropic voxels at multi-detector row CT. Radiology 2005;235(3):879-85.
Pedersen 2001
Prystowsky 2005
Puylaert 1986
Rehman 2011
  • Rehman H, Rao AM, Ahmed I. Single incision versus conventional multi-incision appendicectomy for suspected appendicitis. Cochrane Database of Systematic Reviews 2011, Issue 7. [DOI: 10.1002/14651858.CD009022.pub2]
Reitsma 2005
  • Reitsma JB, Glas AS, Rutjes AW, Scholten RJ, Bossuyt PM, Zwinderman AH. Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol 2005;58:982-90.
Roberts 2011
  • Roberts KE, Solomon D, Mirensky T, Silasi DA, Duffy AJ, Rutherford T, et al. Pure Transvaginal Appendectomy Versus Traditional Laparoscopic Appendectomy for Acute Appendicitis: A Prospective Cohort Study. Ann Surg 2011;255:266-9.
Rud 2012
  • Rud B, Olafsson L, Vejborg TS, Wilhelmsen M, Reitsma JB, Rappeport ED, et al. Diagnostic accuracy of Computed Tomography for Appendicitis in Adults. Cochrane Database of Systematic Reviews 2012, Issue 7. [DOI: 10.1002/14651858.CD009977]
Rutter 2001
Sauerland 2010
Smith 2004
Swank 2011
Varadhan 2010
Wagner 1996
Wan 2009
  • Wan MJ, Krahn M, Ungar WJ, Caku E, Sung L, Medina LS, Doria AS. Acute appendicitis in young children: cost-effectiveness of US versus CT in diagnosis--a Markov decision analytic mode. Radiology 2009;250:378-86.
Wilms 2011
Yabunaka 2007