Intervention Review

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Hyaluronidase for reducing perineal trauma

  1. Fan Zhou1,
  2. Xiao Dong Wang1,*,
  3. Jing Li2,
  4. Gui Qiong Huang1,
  5. Bing Xin Gao1

Editorial Group: Cochrane Pregnancy and Childbirth Group

Published Online: 5 FEB 2014

Assessed as up-to-date: 1 APR 2013

DOI: 10.1002/14651858.CD010441.pub2


How to Cite

Zhou F, Wang XD, Li J, Huang GQ, Gao BX. Hyaluronidase for reducing perineal trauma. Cochrane Database of Systematic Reviews 2014, Issue 2. Art. No.: CD010441. DOI: 10.1002/14651858.CD010441.pub2.

Author Information

  1. 1

    West China Second University Hospital, Sichuan University, Department of Obstetrics and Gynaecology, Chengdu, Sichuan, China

  2. 2

    West China Hospital, Sichuan University, Chinese Cochrane Centre, Chengdu, Sichuan, China

*Xiao Dong Wang, Department of Obstetrics and Gynaecology, West China Second University Hospital, Sichuan University, Renmin Nan Road, Chengdu, Sichuan, 610041, China. drwangxiaodong@126.com. drwangxiaodong@obgyn.com.

Publication History

  1. Publication Status: New
  2. Published Online: 5 FEB 2014

SEARCH

[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. 'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Figure 3]
Figure 3. 'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 HAase injection versus control, Outcome 1 Incidence of perineal trauma.
[Analysis 1.2]
Analysis 1.2. Comparison 1 HAase injection versus control, Outcome 2 Incidence of episiotomy.
[Analysis 1.3]
Analysis 1.3. Comparison 1 HAase injection versus control, Outcome 3 Incidence of first and second degree perineal lacerations.
[Analysis 1.4]
Analysis 1.4. Comparison 1 HAase injection versus control, Outcome 4 Incidence of third and fourth degree perineal lacerations.
[Analysis 2.1]
Analysis 2.1. Comparison 2 HAase injection versus placebo injection, Outcome 1 Incidence of perineal trauma.
[Analysis 2.2]
Analysis 2.2. Comparison 2 HAase injection versus placebo injection, Outcome 2 Incidence of episiotomy.
[Analysis 2.3]
Analysis 2.3. Comparison 2 HAase injection versus placebo injection, Outcome 3 Incidence of first and second degree perineal lacerations.
[Analysis 2.4]
Analysis 2.4. Comparison 2 HAase injection versus placebo injection, Outcome 4 Incidence of third and fourth degree perineal trauma.
[Analysis 3.1]
Analysis 3.1. Comparison 3 HAase injection versus no intervention, Outcome 1 Incidence of perineal trauma.
[Analysis 3.2]
Analysis 3.2. Comparison 3 HAase injection versus no intervention, Outcome 2 Incidence of episiotomy.
[Analysis 3.3]
Analysis 3.3. Comparison 3 HAase injection versus no intervention, Outcome 3 Incidence of first and second degree perineal lacerations.
[Analysis 3.4]
Analysis 3.4. Comparison 3 HAase injection versus no intervention, Outcome 4 Incidence of third and fourth degree perineal trauma.